Effectiveness and safety of endoscopy for treatment of surgical site infection: A randomized control trial

Wang,Hailong; Dou,Xinli; Hu,Xiangping; Yu,Jinsheng; Wang,Shaoshan

doi:10.3892/etm.2014.2028

December-2014 Volume 8 Issue 6

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December-2014 Volume 8 Issue 6

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Article

Effectiveness and safety of endoscopy for treatment of surgical site infection: A randomized control trial

Authors:
- Hailong Wang
- Xinli Dou
- Xiangping Hu
- Jinsheng Yu
- Shaoshan Wang
View Affiliations / Copyright

Affiliations: Graduate School of Tianjin Medical University, Tianjin 300270, P.R. China, Department of Oncology, Tianjin Binhai New Area Dagang Hospital, Tianjin 300270, P.R. China
Pages: 1727-1730
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Published online on: October 17, 2014

https://doi.org/10.3892/etm.2014.2028
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Abstract

The aim of this randomized control study was to evaluate the effectiveness and safety of endoscopy for the treatment of surgical site infection (SSI), compared with conventional therapy. One hundred and six patients who were diagnosed with severe SSI were included in the study, performed from May 2005 to July 2012 at Tianjin Binhai New Area Dagang Hospital, China. Patients were randomly divided into two groups: 57 patients in group A treated by endoscopy and 49 patients in group B treated by conventional therapy for SSI. The primary outcome was the healing period of the wound; the secondary outcomes were the blood loss following surgery, visual analog scale (VAS) measurement, volume of irrigation saline during surgery, rate of skin transplantation, length of hospital stay and other complications. The mean wound healing time was significantly less in group A (10.0±2.5 days) than in group B (19.4±5.2 days). The mean VAS score 7 days after surgery in group A was significantly less compared with group B. The intra‑operative blood loss, intra‑operative volume of irrigation saline and length of the hospital stay were significantly reduced in group A compared with group B. No significant differences between the groups were revealed in terms of the duration of surgery and the clinical complications. This study demonstrated that the endoscopy procedure for the treatment of SSI reduces the wound healing time compared with that of traditional surgery, without increasing any risk of clinical events. The present study showed that endoscopy was not only effective but also safe in the therapy of serious SSI. However, a further randomized control trial is necessary to testify our conclusions.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Effectiveness and safety of endoscopy for treatment of surgical site infection: A randomized control trial

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