Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models

  • Authors:
    • Yongqiang  Liang
    • Haoyan  Li
    • Jiang  Xu
    • Xin  Li
    • Xinchang  Li
    • Yuting  Yan
    • Mengchun  Qi
    • Min  Hu
  • View Affiliations

  • Published online on: October 30, 2014     https://doi.org/10.3892/etm.2014.2038
  • Pages: 172-176
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Abstract

Osteopenia, a preclinical state of osteoporosis, restricts the application of adult orthodontic implant anchorage and tooth implantation. Strontium (Sr) is able to promote bone formation and inhibit bone absorption. The aim of the present study was to evaluate a new method for improving the success rate of dental implantation. In this study, an electrochemical deposition (ECD) method was used to prepare a Sr coating on a titanium implant. The coating composition was investigated by energy dispersive X‑ray spectroscopy and X‑ray diffraction, and the surface morphology of the coating was studied using scanning electron microscopy. A total of 24 Sprague‑Dawley rats received bilateral ovariectomy (OVX) and an additional 12 rats underwent a sham surgery. All rats were then implanted in the bilateral tibiae with titanium mini-implants with or without a Sr coating. The results of histological examination and a fluorescence double labeling assay showed strong new bone formation with a wider zone between the double labels, a higher rate of bone mineralization and better osseointegration in the OVX rats that received Sr‑coated implants compared with the OVX rats that received uncoated implants. The study indicates that Sr coatings are easily applied by an ECD method, and that Sr coatings have a promoting effect on implant osseointegration in animals with osteopenia.
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January-2015
Volume 9 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Liang Y, Li H, Xu J, Li X, Li X, Yan Y, Qi M and Hu M: Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models. Exp Ther Med 9: 172-176, 2015
APA
Liang, Y., Li, H., Xu, J., Li, X., Li, X., Yan, Y. ... Hu, M. (2015). Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models. Experimental and Therapeutic Medicine, 9, 172-176. https://doi.org/10.3892/etm.2014.2038
MLA
Liang, Y., Li, H., Xu, J., Li, X., Li, X., Yan, Y., Qi, M., Hu, M."Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models". Experimental and Therapeutic Medicine 9.1 (2015): 172-176.
Chicago
Liang, Y., Li, H., Xu, J., Li, X., Li, X., Yan, Y., Qi, M., Hu, M."Strontium coating by electrochemical deposition improves implant osseointegration in osteopenic models". Experimental and Therapeutic Medicine 9, no. 1 (2015): 172-176. https://doi.org/10.3892/etm.2014.2038