Effect of low glycemic index food and postprandial exercise on blood glucose level, oxidative stress and antioxidant capacity

Kasuya,Noriaki; Ohta,Shoichiro; Takanami,Yoshikazu; Kawai,Yukari; Inoue,Yutaka; Murata,Isamu; Kanamoto,Ikuo

doi:10.3892/etm.2015.2228

April-2015 Volume 9 Issue 4

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April-2015 Volume 9 Issue 4

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Article

Effect of low glycemic index food and postprandial exercise on blood glucose level, oxidative stress and antioxidant capacity

Authors:
- Noriaki Kasuya
- Shoichiro Ohta
- Yoshikazu Takanami
- Yukari Kawai
- Yutaka Inoue
- Isamu Murata
- Ikuo Kanamoto
View Affiliations / Copyright

Affiliations: Laboratory of Drug Safety Management, Division of Pharmaceutical Sciences, Josai University, Sakado, Saitama 350‑0295, Japan, Department of Urology, Kan‑Etsu Hospital, Tsurugashima, Saitama 350‑2213, Japan, Department of Food Science, Otsuma Women's University, Tokyo 102‑8357, Japan, Louis Pasteur Center for Medical Research, Kyoto 606‑8225, Japan
Pages: 1201-1204
|
Published online on: January 28, 2015

https://doi.org/10.3892/etm.2015.2228
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Abstract

Low glycemic index (GI) food and postprandial exercise are non‑drug therapies for improving postprandial hyperglycemia. The present randomized, crossover study investigated the effect of low GI food combined with postprandial exercise on postprandial blood glucose level, oxidative stress and antioxidant capacity. A total of 13 healthy subjects were each used in four experiments: i) rice only (control), ii) salad prior to rice (LGI), iii) exercise following rice (EX) and iv) salad prior to rice and exercise following rice (MIX). The blood glucose level, oxidative stress and antioxidant capacity were then measured. At 60 min after the meal, the blood glucose level was observed to be increased in the MIX group compared with that in the LGI group. Furthermore, at 180 min, the antioxidant capacity was found to be reduced in the MIX group compared with those of the LGI and EX groups. These findings suggest that low GI food combined with postprandial exercise does not improve postprandial hyperglycemia. It may be necessary to establish optimal timing and intensity when combining low GI food with postprandial exercise to improve postprandial hyperglycemia.

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1	Huxley R, Barzi F and Woodward M: Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies. BMJ. 332:73–78. 2006. View Article : Google Scholar :
2	Haffner SM, Lehto S, Rönnemaa T, Pyörälä K and Laakso M: Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 339:229–234. 1998. View Article : Google Scholar : PubMed/NCBI
3	Niskanen L, Turpeinen A, Penttilä I and Uusitupa MI: Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis. Diabetes Care. 21:1861–1969. 1998. View Article : Google Scholar : PubMed/NCBI
4	DECODE Study Group, the European Diabetes Epidemiology Group. Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria. Arch Intern Med. 161:397–405. 2001. View Article : Google Scholar : PubMed/NCBI
5	Ceriello A, Falleti E, Motz E, et al: Hyperglycemia-induced circulating ICAM-1 increase in diabetes mellitus: the possible role of oxidative stress. Horm Metab Res. 30:146–149. 1998. View Article : Google Scholar : PubMed/NCBI
6	Nappo F, Esposito K, Cioffi M, et al: Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals. J Am Coll Cardiol. 39:1145–50. 2002. View Article : Google Scholar : PubMed/NCBI
7	Esposito K, Nappo F, Marfella R, et al: Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation. 106:2067–2072. 2002. View Article : Google Scholar : PubMed/NCBI
8	Marfella R, Quagliaro L, Nappo F, Ceriello A and Giugliano D: Acute hyperglycemia induces an oxidative stress in healthy subjects. J Clin Invest. 108:635–636. 2001. View Article : Google Scholar : PubMed/NCBI
9	Williams SB, Goldfine AB, Timimi FK, et al: Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation. 97:1695–1701. 1998. View Article : Google Scholar : PubMed/NCBI
10	Opperman AM, Venter CS, Oosthuizen W, Thompson RL and Vorster HH: Meta-analysis of the health effects of using the glycaemic index in meal-planning. Br J Nutr. 92:367–381. 2004. View Article : Google Scholar : PubMed/NCBI
11	Kanamoto I, Inoue Y, Moriuchi T, et al: Effect of differences in low glycemic index food intake sequence on plasma glucose profile. J Jpn Diabetes Soc. 53:96–101. 2010.
12	Lu ZX, Walker KZ, Muir JG, Mascara T and O’Dea K: Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects. Am J Clin Nutr. 71:1123–1128. 2000.PubMed/NCBI
13	Weickert MO, Möhlig M, Schöfl C, et al: Cereal fiber improves whole-body insulin sensitivity in overweight and obese women. Diabetes Care. 29:775–780. 2006. View Article : Google Scholar : PubMed/NCBI
14	Paniagua JA, de la Sacristana AG, Sánchez E, et al: A MUFA-rich diet improves posprandial glucose, lipid and GLP-1 responses in insulin-resistant subjects. J Am Coll Nutr. 26:434–444. 2007. View Article : Google Scholar : PubMed/NCBI
15	Ostman E, Granfeldt Y, Persson L and Björck I: Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. Eur J Clin Nutr. 59:983–988. 2005. View Article : Google Scholar : PubMed/NCBI
16	Larsen JJ, Dela F, Kjaer M and Galbo H: The effect of moderate exercise on postprandial glucose homeostasis in NIDDM patients. Diabetologia. 40:447–453. 1997. View Article : Google Scholar : PubMed/NCBI
17	Viollet B, Lantier L, Devin-Leclerc J, et al: Targeting the AMPK pathway for the treatment of Type 2 diabetes. Front Biosci (Landmark Ed). 14:3380–3400. 2009. View Article : Google Scholar
18	Poirier P, Tremblay A, Catellier C, et al: Impact of time interval from the last meal on glucose response to exercise in subjects with type 2 diabetes. J Clin Endocrinol Metab. 85:2860–2864. 2000.PubMed/NCBI
19	Ceriello A, Bortolotti N, Motz E, et al: Meal-generated oxidative stress in type 2 diabetic patients. Diabetes Care. 21:1529–1533. 1998. View Article : Google Scholar : PubMed/NCBI
20	Castañer O, Covas MI, Khymenets O, Nyyssonen K, Konstantinidou V, Zunft HF, de la Torre R, Muñoz-Aguayo D, Vila J and Fitó M: Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans. Am J Clin Nutr. 95:1238–1244. 2012. View Article : Google Scholar : PubMed/NCBI
21	Kojda G and Hambrecht R: Molecular mechanisms of vascular adaptations to exercise: Physical activity as an effective antioxidant therapy? Cardiovasc Res. 67:187–197. 2005. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Effect of low glycemic index food and postprandial exercise on blood glucose level, oxidative stress and antioxidant capacity

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