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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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June-2015 Volume 9 Issue 6

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Case Report

Hepatoid adenocarcinoma of the stomach: A case report and literature review

  • Authors:
    • Xiao-Mei Liu
    • Gui-Qiu Chen
    • Shun-Li Li
    • Tian-Shu Zai
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, No. 461 Clinical Department of No. 208 Hospital of PLA, Changchun, Jilin 130062, P.R. China, Department of Pathology, China‑Japan Union Hospital, Jilin University, Changchun, Jilin 130033, P.R. China, Department of Surgery, No. 461 Clinical Department of No. 208 Hospital of PLA, Changchun, Jilin 130062, P.R. China, Norman Bethune College of Medicine, Jilin University, Changchun, Jilin 130033, P.R. China
  • Pages: 2133-2136
    |
    Published online on: March 30, 2015
       https://doi.org/10.3892/etm.2015.2393
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Abstract

Hepatoid adenocarcinoma (HAC) is a rare form of gastric cancer that has unique clinicopathological features and an extremely poor prognosis. The present case report describes a patient who was referred to the No. 461 Hospital of PLA (Changchun, China) due to nausea and occasional vomiting of acid/water. The patient was diagnosed with gastric signet‑ring cell carcinoma and surgery was recommended. A total gastrectomy was performed on the operable lesion. Histopathological analysis revealed that the tumors exhibited two pathological changes: HAC and signet‑ring cell carcinoma differentiation. Furthermore, the tumor cells were immunohistochemically positive for α-fetoprotein, cytokeratin low/high molecular weight, Cam5.2, cytokeratin 7, p53, epithelial membrane antigen and carcinoembryonic antigen. Previous studies and our experience have suggested that HAC is an aggressive type of adenocarcinoma; however, radical surgery and chemotherapy may positively impact clinical outcomes.
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Copy and paste a formatted citation
Spandidos Publications style
Liu X, Chen G, Li S and Zai T: Hepatoid adenocarcinoma of the stomach: A case report and literature review. Exp Ther Med 9: 2133-2136, 2015.
APA
Liu, X., Chen, G., Li, S., & Zai, T. (2015). Hepatoid adenocarcinoma of the stomach: A case report and literature review. Experimental and Therapeutic Medicine, 9, 2133-2136. https://doi.org/10.3892/etm.2015.2393
MLA
Liu, X., Chen, G., Li, S., Zai, T."Hepatoid adenocarcinoma of the stomach: A case report and literature review". Experimental and Therapeutic Medicine 9.6 (2015): 2133-2136.
Chicago
Liu, X., Chen, G., Li, S., Zai, T."Hepatoid adenocarcinoma of the stomach: A case report and literature review". Experimental and Therapeutic Medicine 9, no. 6 (2015): 2133-2136. https://doi.org/10.3892/etm.2015.2393
Copy and paste a formatted citation
x
Spandidos Publications style
Liu X, Chen G, Li S and Zai T: Hepatoid adenocarcinoma of the stomach: A case report and literature review. Exp Ther Med 9: 2133-2136, 2015.
APA
Liu, X., Chen, G., Li, S., & Zai, T. (2015). Hepatoid adenocarcinoma of the stomach: A case report and literature review. Experimental and Therapeutic Medicine, 9, 2133-2136. https://doi.org/10.3892/etm.2015.2393
MLA
Liu, X., Chen, G., Li, S., Zai, T."Hepatoid adenocarcinoma of the stomach: A case report and literature review". Experimental and Therapeutic Medicine 9.6 (2015): 2133-2136.
Chicago
Liu, X., Chen, G., Li, S., Zai, T."Hepatoid adenocarcinoma of the stomach: A case report and literature review". Experimental and Therapeutic Medicine 9, no. 6 (2015): 2133-2136. https://doi.org/10.3892/etm.2015.2393
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