Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
June-2015 Volume 9 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
June-2015 Volume 9 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes

  • Authors:
    • Wei‑Dong Wang
    • Lin Xing
    • Jun‑Ru Teng
    • Shuo Li
    • Na Mi
  • View Affiliations / Copyright

    Affiliations: Department of Endocrinology, The Third People's Hospital of Jinan, Jinan, Shandong 250132, P.R. China, Department of Clinical Laboratory, The Third People's Hospital of Jinan, Jinan, Shandong 250132, P.R. China
  • Pages: 2219-2224
    |
    Published online on: April 17, 2015
       https://doi.org/10.3892/etm.2015.2428
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of this study was to investigate the effects of basal insulin application on the serum visfatin and adiponectin (APN) levels of patients with type 2 diabetes mellitus (T2DM). A total of 200 patients with T2DM, who were diagnosed in The Third People's Hospital of Jinan (glycosylated hemoglobin ≥7%), were randomly divided into treatment and control groups. The patients used only oral hypoglycemic drugs and had never received insulin therapy. In the treatment group, basal insulin was administered in combination with the original application of oral hypoglycemic drugs, whereas the control group maintained the original use of oral hypoglycemic drugs or took other oral hypoglycemic agents. The body mass index and fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, visfatin, APN and blood lipid levels of the patients were examined prior to the treatment and six months later. The drug and insulin doses in the treatment group were adjusted according to the patients' blood glucose, which allowed the fasting and postprandial blood glucose levels to attain the standards. The fasting and postprandial blood glucose levels in the control group also achieved the standards. It was found that the six‑month application of basal insulin could significantly decrease the glycosylated hemoglobin and significantly increase the serum APN levels; the serum visfatin levels, however, remained unchanged. The immediate application of basal insulin could facilitate the attainment of glycosylated hemoglobin standards in T2DM and could increase the plasma APN levels, preventing diabetic vascular complications.
View Figures
View References

1 

Robetson RP, Harmon J, Tran PO, Tanaka Y and Takahashi H: Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathi-one connection. Diabetes. 52:581–587. 2003. View Article : Google Scholar : PubMed/NCBI

2 

Cobitz AR and Ambery P: Medical management of hyperglycemia in type 2 type diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Response to Nathan et al. Diabetes Care. 32:e582009. View Article : Google Scholar

3 

Swinnen SG, Dain MP, Aronson R, et al: A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugs. Diabetes Care. 33:1176–1178. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Riddle MC, Rosenstock J and Gerich J: Insulin Glargine 4002 Study Investigators: The treat-to-target trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care. 26:3080–3086. 2003. View Article : Google Scholar : PubMed/NCBI

5 

Janka HU, Plewe G, Riddle MC, et al: Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes. Diabetes Care. 28:254–259. 2005. View Article : Google Scholar : PubMed/NCBI

6 

Yki-Jarvinen H, Kauppinen-Makelin R, Tiikkainen M, et al: Insulin glargine or NPH combined with metformin in type 2 diabetes: The LANMET study. Diabetologia. 49:442–451. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Lepore M, Pampanelli S, Fanelli C, et al: Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro. Diabetes. 49:2142–2148. 2000. View Article : Google Scholar : PubMed/NCBI

8 

Stentz FB, Umpierrez GE, Cuervo R and Kitabchi AE: Proinflammatory cyto-kines, markers of cardiovascular risks, oxidative stress, and lip id peroxidetion in patients with hyperglycemic crises. Diabetes. 53:2079–2086. 2004. View Article : Google Scholar : PubMed/NCBI

9 

Forouhi NG, Sattar N and McKeigue PM: Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians. Int J Obes Relat Metab Disord. 25:1327–1331. 2001. View Article : Google Scholar : PubMed/NCBI

10 

Nayak BS, Ramsingh D, Gooding S, et al: Plasma adiponectin levels are related to obesity, inflammation, blood lipids and insulin in type 2 diabetic and non-diabetic Trinidadians. Prim Care Diabetes. 4:187–192. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Winkler C and Cseh K: Molecular mechanisms and correlations of insulin resistance, obesity, and type 2 diabetes mellitus. Orv Hetil. 150:7717802009.(In Hungarian). View Article : Google Scholar : PubMed/NCBI

12 

Inoue M, Maehata E, Yano M, Taniyama M and Suzuki S: Correlation between the adiponectin-leptin ratio and parameters of insulin resistance in patients with type 2 diabetes. Metabolism. 54:281–286. 2005. View Article : Google Scholar : PubMed/NCBI

13 

Lindsav RS, Funabashi T, Hanson RL, et al: Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet. 360:57–58. 2002. View Article : Google Scholar : PubMed/NCBI

14 

Kubota N, Terauchi Y, Yamauchi T, et al: Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem. 277:25863–25866. 2002. View Article : Google Scholar : PubMed/NCBI

15 

Stefan N, Stumvoll M, Vozarova B, et al: Plasma adiponectin and endogenous glucose production in humans. Diabetes Care. 26:3315–3319. 2003. View Article : Google Scholar : PubMed/NCBI

16 

Hivert MF, Sullivan LM, Shrader P, et al: Insulin resistance influences the association of adiponectin levels with diabetes incidence in two population-based cohorts: the Cooperative Health research in the Region of Augsburg (KORA) S4/F4 study and the Framingham Offspring Study. Diabetologia. 54:1019–1024. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Lau CH and Muniandy S: Adiponectin and resistin gene polymorphisms in association with their respective adipokine levels. Ann Hum Genet. 75:370–382. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Chu CH, Lam HC, Lee JK, et al: Hyperthyroidism-associated insulin resistance is not mediated by adiponectin levels. J Thyroid Res. 2011:1947212011. View Article : Google Scholar : PubMed/NCBI

19 

Wolf AM, Wolf D, Rumpold H, Enrich B and Tilg H: Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes. Biochem Biophys Res Commun. 323:630–635. 2004. View Article : Google Scholar : PubMed/NCBI

20 

Imai S: Nicotinamide phosphoribosyltansferase (Nampt): a link between NAD biology, metabolism, and diseases. Curr Pharm Des. 15:20–28. 2009. View Article : Google Scholar : PubMed/NCBI

21 

Lin Y, Berg AH, Iyengar P, et al: The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. J Biol Chem. 280:4617–4626. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Yang W, Lu J, Weng J, et al: Prevalence of diabetes among men and women in China. N Engl J Med. 362:1090–1101. 2010. View Article : Google Scholar : PubMed/NCBI

23 

Chen MP, Chung FM, Chang DM, et al: Elevated plasma level of vifatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 91:295–299. 2006. View Article : Google Scholar : PubMed/NCBI

24 

Jalovaara K, Santaniemi M, Timonen M, et al: Low serum adiponectin level as a predictor of impaired glucose regulation and type 2 diabetes mellitus in a middle-aged Finnish population. Metabolism. 57:1130–1134. 2008. View Article : Google Scholar : PubMed/NCBI

25 

Su SC, Pei D, Hsieh CH, et al: Circulating pro-inflammatory cytokines and adiponectin in young men with type 2 diabetes. Acta Diabetol. 48:113–119. 2011. View Article : Google Scholar : PubMed/NCBI

26 

Wong WT, Tian XY, Xu A, et al: Adiponectin is required for PPAR൞-mediated improvement of endothelial function in diabetic mice. Cell Metab. 14:104–105. 2011. View Article : Google Scholar : PubMed/NCBI

27 

Choudhary S, Sinha S, Zhao Y, et al: NF-kappaB-inducing kinase (NIK) mediates skeletal muscle insulin resistance: blockade by adiponectin. Endocrinology. 152:3622–3627. 2011. View Article : Google Scholar : PubMed/NCBI

28 

Skrabal CA, Czaja J, Honz K, et al: Adiponectin - its potential to predict and prevent coronary artery disease. Thorac Cardiovasc Surg. 59:201–206. 2011. View Article : Google Scholar : PubMed/NCBI

29 

Kyriazi E, Tsiotra PC, Boutati E, et al: Effects of adiponectin in TNF-α, IL-6, IL-10 cytokine production from coronary artery disease macrophages. Horm Metab Res. 43:537–544. 2011. View Article : Google Scholar : PubMed/NCBI

30 

Tesauro M, Rizza S, Iantorno M, et al: Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus. Metabolism. 56:413–419. 2007. View Article : Google Scholar : PubMed/NCBI

31 

Pickup JC: Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care. 27:813–823. 2004. View Article : Google Scholar : PubMed/NCBI

32 

Donath MY and Shoelson SE: Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 11:98–107. 2011. View Article : Google Scholar : PubMed/NCBI

33 

Cai XJ, Chen L, Li L, et al: Adiponectin inhibits lipopolysaccharide-induced adventitial fibroblast migration and transition to myofibroblasts via AdipoR1-AMPK-iNOS pathway. Mol Endocrinol. 24:218–228. 2010. View Article : Google Scholar : PubMed/NCBI

34 

Fagerberg B, Kellis D, Bergstrom G and Behre CJ: Adiponectin in relation to insulin sensitivity and insulin secretion in the development of type 2 diabetes: a prospective study in 64-year-old women. J Intern Med. 269:636–643. 2011. View Article : Google Scholar : PubMed/NCBI

35 

Ran J, Xiong X, Liu W, et al: Increased plasma adiponectin closely associates with vascular endothelial dysfunction in type 2 diabetic patients with diabetic nephropathy. Diabetes Res Clin Pract. 88:177–183. 2010. View Article : Google Scholar : PubMed/NCBI

36 

Curat CA, Wegner V, Sengenes C, et al: Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin. Diabetologia. 49:744–747. 2006. View Article : Google Scholar : PubMed/NCBI

37 

Dahl TB, Yndestad A, Skjelland M, et al: Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization. Circulation. 115:972–980. 2007. View Article : Google Scholar : PubMed/NCBI

38 

Adya R, Tan BK, Chen J and Randeva HS: Nuclear factor-kappaB induction by visfatin in human vascular endothelial ceils: its role in MMP-2/9 production and activation. Diabetes Care. 31:758–760. 2008. View Article : Google Scholar : PubMed/NCBI

39 

Kim SR, Jung YH, Park HJ, et al: Upregulation of thromboxane synthase mediates visfatin-induced interleukin-8 expression and angiogenic activity in endothelial cells. Biochem Biophys Res Commun. 418:662–668. 2012. View Article : Google Scholar : PubMed/NCBI

40 

Kadoglou NP, Sailer N, Moumtzouoglou A, et al: Visfatin (nampt) and ghrelin as novel markers of carotid atherosclerosis in patients with type 2 diabetes. Exp Clin Endocrinol Diabetes. 118:75–80. 2010. View Article : Google Scholar : PubMed/NCBI

41 

Sethi JK and Vidal-Puig A: Visfatin: the missing link between intra-abdominal obesity and diabetes? Trends Mol Med. 11:344–347. 2005. View Article : Google Scholar : PubMed/NCBI

42 

Samal B, Sun Y, Stearns G, Xie C, Suggs S and McNiece I: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Mol Cell Biol. 14:1431–1437. 1994.PubMed/NCBI

43 

Hug C and Lodish HF: Medicine. Visfatin: a new adipokine. Science. 307:366–367. 2005. View Article : Google Scholar : PubMed/NCBI

44 

Retnakaran R, Youn BS, Liu Y, et al: Correlation of circulating full-length visfatin (PBEF/NAMPT) with metabolic parameters in subjects with and without diabetes: a cross-sectional study. Clin Endocrinol (Oxf). 69:885–893. 2008. View Article : Google Scholar : PubMed/NCBI

45 

Holman RR, Paul SK, Bethel MA, Matthews DR and Neil HA: 10-year follow-up of intensive glucose control in 2 type diabetes. N Engl J Med. 359:1577–1589. 2008. View Article : Google Scholar : PubMed/NCBI

46 

Forst T, Larbig M, Hobberg C, et al: Adding insulin glargine vs. NPH insulin to metformin results in a more efficient postprandial beta-cell protection in individuals with type 2 diabetes. Diabetes Obes Metab. 12:437–441. 2010. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Wang WD, Xing L, Teng JR, Li S and Mi N: Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes. Exp Ther Med 9: 2219-2224, 2015.
APA
Wang, W., Xing, L., Teng, J., Li, S., & Mi, N. (2015). Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes. Experimental and Therapeutic Medicine, 9, 2219-2224. https://doi.org/10.3892/etm.2015.2428
MLA
Wang, W., Xing, L., Teng, J., Li, S., Mi, N."Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes". Experimental and Therapeutic Medicine 9.6 (2015): 2219-2224.
Chicago
Wang, W., Xing, L., Teng, J., Li, S., Mi, N."Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes". Experimental and Therapeutic Medicine 9, no. 6 (2015): 2219-2224. https://doi.org/10.3892/etm.2015.2428
Copy and paste a formatted citation
x
Spandidos Publications style
Wang WD, Xing L, Teng JR, Li S and Mi N: Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes. Exp Ther Med 9: 2219-2224, 2015.
APA
Wang, W., Xing, L., Teng, J., Li, S., & Mi, N. (2015). Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes. Experimental and Therapeutic Medicine, 9, 2219-2224. https://doi.org/10.3892/etm.2015.2428
MLA
Wang, W., Xing, L., Teng, J., Li, S., Mi, N."Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes". Experimental and Therapeutic Medicine 9.6 (2015): 2219-2224.
Chicago
Wang, W., Xing, L., Teng, J., Li, S., Mi, N."Effects of basal insulin application on serum visfatin and adiponectin levels in type 2 diabetes". Experimental and Therapeutic Medicine 9, no. 6 (2015): 2219-2224. https://doi.org/10.3892/etm.2015.2428
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team