Incremental value of resting three-dimensional speckle-tracking echocardiography in detecting coronary artery disease

Sun,You‑Jing; Wang,Fang; Zhang,Rui‑Sheng; Wang,Hai‑Yan; Yang,Chen‑Guang; Cai,Jie; Zang,Wei‑Er; Li,Ming‑Zhou; Qi,Xin; Li,Jing

doi:10.3892/etm.2015.2435

June-2015 Volume 9 Issue 6

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June-2015 Volume 9 Issue 6

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Article Open Access

Incremental value of resting three-dimensional speckle-tracking echocardiography in detecting coronary artery disease

Authors:
- You‑Jing Sun
- Fang Wang
- Rui‑Sheng Zhang
- Hai‑Yan Wang
- Chen‑Guang Yang
- Jie Cai
- Wei‑Er Zang
- Ming‑Zhou Li
- Xin Qi
- Jing Li
View Affiliations / Copyright

Affiliations: Department of Ultrasonography, Beijing Hospital, Beijing 100730, P.R. China, Department of Cardiology, Beijing Hospital, Beijing 100730, P.R. China

Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 2043-2046
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Published online on: April 20, 2015

https://doi.org/10.3892/etm.2015.2435
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Abstract

The aim of the present study was to investigate the incremental value of resting three-dimensional speckle-tracking echocardiography (3D-STE) in the detection of early‑stage left ventricular dysfunction in patients with coronary artery disease (CAD). A total of 110 patients suspected of having CAD were recruited. All patients underwent 3D‑STE and coronary artery angiography (CAG). They were divided to a CAD group and a normal group according to the results of CAG. Using 3D‑STE software, the peak values of longitudinal strain (LS), circumferential strain (CS), radial strain (RS) and area strain (AS) and the time to peak value of these strains (T‑LS, T‑CS, T‑RS and T‑AS) were measured. A receiver operator characteristic curve (ROC) was used to analyze the sensitivity of these strains for the diagnosis of CAD. ROC analysis indicated that T‑LS and composite indices combining the peak strain value and time to peak of LS, CS and AS have diagnostic value for the early detection of CAD; the area under the curve (AUC) values were 0.667, 0.692, 0.621 and 0.672 respectively (P<0.005). The composite index of longitudinal strain demonstrated the highest diagnostic value for CAD with 62% sensitivity and 76% specificity. These results indicate that 3D-STE has incremental value for the diagnosis of CAD in patients at rest.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Incremental value of resting three-dimensional speckle-tracking echocardiography in detecting coronary artery disease

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