|
1
|
Beckmann-Knopp S, Rietbrock S, Weyhenmeyer
R, Böcker RH, Beckurts KT, Lang W, Hunz M and Fuhr U: Inhibitory
effects of silibinin on cytochrome P-450 enzymes in human liver
microsomes. Pharmacol Toxicol. 86:250–256. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Abelson HT, Fosburg MT, Beardsley GP,
Goorin AM, Gorka C, Link M and Link D: Methotrexate-induced renal
impairment: Clinical studies and rescue from systemic toxicity with
high-dose leucovorin and thymidine. J Clin Oncol. 1:208–216.
1983.PubMed/NCBI
|
|
3
|
Ohbayashi M, Kubota S, Kawase A, Kohyama
N, Kobayashi Y and Yamamoto T: Involvement of
epithelial-mesenchymal transition in methotrexate-induced pulmonary
fibrosis. J Toxicol Sci. 39:319–330. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Oktem F, Yilmaz HR, Ozguner F, Olgar S,
Ayata A, Uzare E and Uz E: Metothrexate-induced renal oxidative
stres in rats: The role of a novel antioxidant caffeic acid
phenethyl ester. Toxicol Ind Health. 22:241–247. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Jahovic N, Cevik H, Sehirli AO, Yegen BC
and Sener G: Melatonin prevents methotrexate-induced hepatorenal
oxidative injury in rats. J Pineal Res. 34:282–287. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kose E, Sapmaz HI, Sarihan E, Vardi N,
Turkoz N and Ekinci N: Beneficial effects of montelukast against
methotrexate-induced liver toxicity: A biochemical and histological
study. ScientificWorldJournal. 2012:9875082012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ozkan E, Yardimci S, Dulundu E, Topaloğlu
U, Sehirli O, Ercan F, Velioglu-Ogunc A and Sener G: Protective
potential of montelukast against hepatic ischemia/reperfusion
injury in rats. J Surg Res. 159:588–594. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Vardi N, Parlakpinar H, Cetin A, Erdogan A
and Ozturk IC: Protective effect of carotene on
methotrexate-induced oxidative liver damage. Toxicol Pathol.
38:592–597. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen PN, Hsieh YS, Chiou HL and Chu SC:
Silibinin inhibits cell invasion through inactivation of both
PI3K-Akt and MAPK signaling pathways. Chem Biol Interact.
156:141–150. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Schümann J, Prockl J, Kiemer AK, Vollmar
AM, Bang R and Tiegs G: Silibinin protects mice from T
cell-dependent liver injury. J Hepatol. 39:333–340. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lim R, Morwood CJ, Barker G and Lappas M:
Effect of silibinin in reducing inflammatory pathways in in
vitro and in vivo models of infection-induced preterm
birth. PLoS One. 9:e925052014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
El Hafny B, Cano N, Piciotti M, Regina A,
Scherrmann JM and Roux F: Role of P-glycoprotein in colchicine and
vinblastine cellular kinetics in an immortalized rat brain
microvessel endothelial cell line. Biochem Pharmacol. 53:1735–1742.
1997. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Ting H, Deep G and Agarwal R: Molecular
mechanisms of silibinin mediated cancer chemoprevention with major
emphasis on prostate cancer. AAPS J. 15:707–716. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ligeret H, Brault A, Vallerand D, Haddad Y
and Haddad PS: Antioxidant and mitochondrial protective effects of
silibinin in cold preservation-warm reperfusion liver injury. J
Ethnopharmacol. 115:507–514. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Mateen S, Raina K and Agarwal R:
Chemopreventive and anti-cancer efficacy of silibinin against
growth and progression of lung cancer. Nutr Cancer. 65 (Suppl
1):3–11. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Nassuato G, Iemmolo RM, Strazzabosco M,
Lirussi F, Deana R, Francesconi MA, Muraca M, Passera D, Fragasso A
and Orlando R: Effect of Silibinin on biliary lipid composition.
Experimental and clinical study. J Hepatol. 12:290–295. 1991.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Sekeroğlu ZA and Sekeroğlu V: Effects of
Viscum album L. extract and quercetin on
methotrexate-induced cyto-genotoxicity in mouse bone-marrow cells.
Mutat Res. 746:56–59. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Imokawa S, Colby TV, Leslie KO and Helmers
RA: Methotrexate pneumonitis: Review of the literature and
histopathological findings in nine patients. Eur Respir J.
15:373–381. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Kim YJ, Song M and Ryu JC: Inflammation in
methotrexate-induced pulmonary toxicity occurs via the p38 MAPK
pathway. Toxicology. 256:183–190. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Pal A, Tewari-Singh N, Gu M, Agarwal C,
Huang J, Day BJ, White CW and Agarwal R: Sulfur mustard analog
induces oxidative stress and activates signaling cascades in the
skin of SKH-1 hairless mice. Free Radic Biol Med. 47:1640–1651.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Tewari-Singh N, Jain AK, Inturi S, Agarwal
C, White CW and Agarwal R: Silibinin attenuates sulfur mustard
analog-induced skin injury by targeting multiple pathways
connecting oxidative stress and inflammation. PLoS One.
7:e461492012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Singh RP and Agarwal R: Mechanisms and
preclinical efficacy of silibinin in preventing skin cancer. Eur J
Cancer. 41:1969–1979. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Deep G and Agarwal R: Antimetastatic
efficacy of silibinin: Molecular mechanisms and therapeutic
potential against cancer. Cancer Metastasis Rev. 29:447–463. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Dhanalakshmi S, Agarwal C, Singh RP and
Agarwal R: Silibinin up-regulates DNA-protein kinase dependent p53
activation to enhance UVB-induced apoptosis in mouse epithelial JB6
cells. J Biol Chem. 280:20375–20383. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mallikarjuna G, Dhanalakshmi S, Singh RP,
Agarwal C and Agarwal R: Silibinin protects against
photocarcinogenesis via modulation of cell cycle regulators,
mitogen-activated protein kinases and Akt signaling. Cancer Res.
64:6349–6356. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hassan W: Methotrexate and liver toxicity:
Role of surveillance liver biopsy. Conflict between guidelines for
rheumatologists and dermatologists. Ann Rheum Dis. 55:273–275.
1996. View Article : Google Scholar : PubMed/NCBI
|
