Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
August-2015 Volume 10 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2015 Volume 10 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Polycythemia vera associated with IgA nephropathy: A case report and literature review

  • Authors:
    • Hong Chen
    • Baohe Zhang
    • Mingxu Li
    • Ruilan Hu
    • Chunhua Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Geriatrics, Navy General Hospital, Beijing 100048, P.R. China, Department of Nephrology, Navy General Hospital, Beijing 100048, P.R. China
  • Pages: 555-560
    |
    Published online on: June 11, 2015
       https://doi.org/10.3892/etm.2015.2572
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

A case of polycythemia vera (PV) associated with immunoglobulin A nephropathy (IgAN) in a 57‑year‑old man is described. The patient had a mild enlargement of the kidneys and elevated serum creatinine level, whereas the glomerular filtration rate was normal. Pathological observation under a light microscope showed mild mesangial hyperplasia. The urinary protein level was found to be positively correlated with changes in blood cell counts. After controlling blood pressure, anti‑platelet, hydroxyurea treatment, the patient's proteinuria decreased and renal function remained in the normal range. PV associated with renal disease is rare and generally considered to be associated with hypervolemia or high‑viscosity‑induced renal hyperperfusion and hyperfiltration. This is a rare case of PV associated with IgAN without a high filtration rate. A review of the clinical features of PV associated with renal disease from previous literature was also conducted. The histological results of the cases varied and included IgAN, focal segmental glomerulosclerosis and membranoproliferative glomerulonephritis.
View Figures

Figure 1

View References

1 

Godfrey AL, Chen E, Pagano F, Silber Y, Campbell PJ and Green AR: Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia. Haematologica. 98:718–721. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Kuriakose E, Vandris K, Wang YL, Chow W, Jones AV, Christos P, Cross NC and Silver RT: Decrease in JAK2 V617F allele burden is not a prerequisite to clinical response in patients with polycythemia vera. Haematologica. 97:538–542. 2012. View Article : Google Scholar : PubMed/NCBI

3 

Okuyama S, Hamai K, Fujishima M, Ohtani H, Komatsuda A, Sawada K and Wakui H: Focal segmental glomerulosclerosis associated with polycythemia vera: report of a case and review of the literature. Clin Nephrol. 68:412–415. 2007. View Article : Google Scholar : PubMed/NCBI

4 

Lee SM, Rao VM, Franklin WA, Schiffer MS, Aronson AJ, Spargo BH and Katz AI: IgA nephropathy: Morphologic predictors of progressive renal disease. Human Pathol. 13:314–322. 1982. View Article : Google Scholar

5 

Kasuno K, Ono T, Kamata T, Kawamura T, Suyama T, Oyama A, Matsushima H, Kuwahara T, Muso E and Sasayama S: IgA nephropathy associated with polycythaemia vera: Accelerated course. Nephrol Dial Transplant. 12:212–215. 1997. View Article : Google Scholar : PubMed/NCBI

6 

Kim MY: A case report of polycythemia vera associated with IgA nephropathy. Korean J Nephrol. 13:977–981. 1994.

7 

Kwon MY: A case report of chronic renal failure caused by IgA nephropathy combined with polycythaemia vera. Korean J Nephrol. 18:843–847. 1999.

8 

Chung J, Park PG and Song KI: IgA nephropathy in a patient with polycythemia vera: Clinical manifestation of chronic renal failure and heavy proteinuria. Am J Nephrol. 22:397–401. 2002. View Article : Google Scholar : PubMed/NCBI

9 

Yaguchi T, Takimoto C, Uchimura H, et al: IgA nephropathy associated with polycythemia vera. Nippon Naika Gakkai Zasshi. 94:1612–1614. 2005.(In Japanese). View Article : Google Scholar : PubMed/NCBI

10 

Tian M, Liu DJ and Li DT: A case report of IgA nephropathy combined with polycythaemia vera treated by mycophenolate mofetil. Shiyong Yaowu Yu Linchuang. 14:358–359. 2011.(In Chinese).

11 

Kanauchi M, Dohi K, Shiiki H, Fujii Y and Ishikawa H: Henoch-Schönlein purpura nephritis associated with polycythemia vera. Intern Med. 33:36–40. 1994. View Article : Google Scholar : PubMed/NCBI

12 

Sharma RK, Kohli HS, Arora P, et al: Focal segmental glomerulosclerosis in a patient with polycythemia rubra vera. Nephron. 69:3611995. View Article : Google Scholar : PubMed/NCBI

13 

Au WY, Chan KW, Lui SL, Lam CC and Kwong YL: Focal segmental glomerulosclerosis and mesangial sclerosis associated with myeloproliferative disorders. Am J Kidney Dis. 34:889–893. 1999. View Article : Google Scholar : PubMed/NCBI

14 

Kosch M, August C, Hausberg M, et al: Focal sclerosis with tip lesions secondary to polycythaemia vera. Nephrol Dial Transplant. 15:1710–1711. 2000. View Article : Google Scholar : PubMed/NCBI

15 

Ulusoy S, Ozkan G, Sönmez M, et al: Absence of hypoalbuminemia despite nephrotic proteinuria in focal segmental glomerulosclerosis secondary to polycythemia vera. Intern Med. 49:2477–2480. 2010. View Article : Google Scholar : PubMed/NCBI

16 

Martín JS, Suárez LG and Martín FG: Focal and segmental glomerulosclerosis associated with polycythemia vera. Nefrologia. 30:138–140. 2010.(In Spanish). PubMed/NCBI

17 

Iyoda M, Ito J, Ajiro Y, et al: Focal segmental glomerulosclerosisin a patient with polycythemia vera. Nippon Jinzo Gakkai Shi. 47:828–833. 2005.(In Japanese). PubMed/NCBI

18 

Cai MS, Wang M, Gan LY and Dong S: Focal segmental glomerulosclerosis in patient with polycythemia vera: One case report. Zhonghua Lao Nian Duo Qi Guan Ji Bing Za Zhi. 10:82–83. 2011.(In Chinese).

19 

Dai ZY, Li YS and Wu GH: The clinial pathobiology analysis of polycythemia vera complicating kidney disease. Zhongguo Zhongxiyi Jiehe Shenbing Zazhi. 9:1004–1005. 2008.(In Chinese).

20 

Nishi Y, Namikoshi T, Sasaki T, et al: Histopathological manifestations of membranoproliferative glomerulonephritis and glomerular expression of plasmalemmal vesicle-associated protein-1 in a patient with polycythemia vera. Clin Nephrol. 74:393–398. 2010.PubMed/NCBI

21 

Fernando BK, Ruwanpathirana HS and Veerasuthen T: A patient with polycythaemia vera associated with membranoproliferative glomerulonephritis. Ceylon Med J. 56:119–120. 2011. View Article : Google Scholar : PubMed/NCBI

22 

Oymak O, Oymak FS, Patiroglu T, et al: Polycythemia vera presenting with rapidly progressive glomerulonephritis and pyoderma gangrenosum. Nephron. 86:346–347. 2000. View Article : Google Scholar : PubMed/NCBI

23 

Ravandi-Kashani F, Cortes J, Talpaz M and Kantarjian HM: Thrombotic microangiopathy associated with interferon therapy for patients with chronic myelogenous leukemia: Coincidence or true side effect? Cancer. 85:2583–2588. 1999. View Article : Google Scholar : PubMed/NCBI

24 

Read NG, Astbury PJ, Evans GO, Goodwin DA and Rowlands A: Nephrotic syndrome associated with N-hydroxyureas, inhibitors of 5-lipoxygenase. Arch Toxicol. 69:480–490. 1995. View Article : Google Scholar : PubMed/NCBI

25 

Makdassy R, Beaufils M, Merier A, Mignon F, Moulonguet-Doleris L and Richet G: Pathologic conditions associated with IgA mesangial nephropathy: Preliminary results. Contrib Nephrol. 40:292–295. 1984. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Chen H, Zhang B, Li M, Hu R and Zhou C: Polycythemia vera associated with IgA nephropathy: A case report and literature review. Exp Ther Med 10: 555-560, 2015.
APA
Chen, H., Zhang, B., Li, M., Hu, R., & Zhou, C. (2015). Polycythemia vera associated with IgA nephropathy: A case report and literature review. Experimental and Therapeutic Medicine, 10, 555-560. https://doi.org/10.3892/etm.2015.2572
MLA
Chen, H., Zhang, B., Li, M., Hu, R., Zhou, C."Polycythemia vera associated with IgA nephropathy: A case report and literature review". Experimental and Therapeutic Medicine 10.2 (2015): 555-560.
Chicago
Chen, H., Zhang, B., Li, M., Hu, R., Zhou, C."Polycythemia vera associated with IgA nephropathy: A case report and literature review". Experimental and Therapeutic Medicine 10, no. 2 (2015): 555-560. https://doi.org/10.3892/etm.2015.2572
Copy and paste a formatted citation
x
Spandidos Publications style
Chen H, Zhang B, Li M, Hu R and Zhou C: Polycythemia vera associated with IgA nephropathy: A case report and literature review. Exp Ther Med 10: 555-560, 2015.
APA
Chen, H., Zhang, B., Li, M., Hu, R., & Zhou, C. (2015). Polycythemia vera associated with IgA nephropathy: A case report and literature review. Experimental and Therapeutic Medicine, 10, 555-560. https://doi.org/10.3892/etm.2015.2572
MLA
Chen, H., Zhang, B., Li, M., Hu, R., Zhou, C."Polycythemia vera associated with IgA nephropathy: A case report and literature review". Experimental and Therapeutic Medicine 10.2 (2015): 555-560.
Chicago
Chen, H., Zhang, B., Li, M., Hu, R., Zhou, C."Polycythemia vera associated with IgA nephropathy: A case report and literature review". Experimental and Therapeutic Medicine 10, no. 2 (2015): 555-560. https://doi.org/10.3892/etm.2015.2572
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team