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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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September-2015 Volume 10 Issue 3

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Case Report

Systemic lupus erythematosus with intestinal perforation: A case report

  • Authors:
    • Yuqing Gu
    • Tao Zhu
    • Yiqing Wang
    • Hongxing Xu
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, Taicang Hospital Affiliated to Soochow University, Taicang, Jiangsu 215400, P.R. China, Department of Intensive Care Unit, Taicang Hospital Affiliated to Soochow University, Taicang, Jiangsu 215400, P.R. China
  • Pages: 1234-1238
    |
    Published online on: July 15, 2015
       https://doi.org/10.3892/etm.2015.2639
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Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease, which can affect almost all systems and organs. Gastrointestinal disorder is one of the most noteworthy complications of patients with SLE. However, gastrointestinal disorder with intestinal perforation is rare, but potentially life‑threatening if not treated promptly. The present study reported a case of SLE with intestinal perforation, where surgical intervention was performed and a crevasse (~3 cm in diameter) was detected in the ileum, ~60 cm from the ileocecal valve. Following surgery, the patient suffered from difficult ventilator weaning, septic shock and intestinal obstruction. The patient was successfully treated and discharged from the hospital after ~4 months of treatment. Intestinal perforation in SLE patients is potentially life‑threatening; early diagnosis and prompt treatment are crucial to the management of this rare complication of SLE.
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1 

Meszaros ZS, Perl A and Faraone SV: Psychiatric symptoms in systemic lupus erythematosus: A systematic review. J Clin Psychiatry. 73:993–1001. 2012. View Article : Google Scholar : PubMed/NCBI

2 

Janessens P, Arnaud L, Galicier L, Mathian A, Hie M, Sene D, Haroche J, Veyssier-Belot C, Huynh-Charlier I and Grenier PA: Lupus enteritis: From clinical findings to therapeutic management. Orphanet J Rare Dis. 8:672013. View Article : Google Scholar : PubMed/NCBI

3 

Malaviya AN, Sharma A, Agarwal D, Kapoor S, Garg S, Singh S and Rawat R: Acute abdomen in SLE. Int J Rheum Dis. 14:98–104. 2011. View Article : Google Scholar : PubMed/NCBI

4 

Chng HH, Tan BE, Teh CL and Lian TY: Major gastrointestinal manifestations in lupus patients in Asia: Lupus enteritis, intestinal pseudo-obstruction and protein-losing gastroenteropathy. Lupus. 19:1404–1413. 2010. View Article : Google Scholar : PubMed/NCBI

5 

Xu D, Yang H, Lai CC, Li P, Zhang X, Yang XO, Zhang FC and Qian JM: Clinical analysis of systemic lupus erythematosus with gastrointestinal manifestations. Lupus. 19:866–869. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Medina F, Ayala A, Jara LJ, Becerra M, Miranda JM and Fraga A: Acute abdomen in systemic lupus erythematosus: The importance of early laparotomy. Am J Med. 103:100–105. 1997. View Article : Google Scholar : PubMed/NCBI

7 

Al-Hakeem MS and McMillen MA: Evaluation of abdominal pain in systemic lupus erythematosus. Am J Surg. 176:291–294. 1998. View Article : Google Scholar : PubMed/NCBI

8 

Tian XP and Zhang X: Gastrointestinal involvement in systemic lupus erythematosus: Insight into pathogenesis, diagnosis and treatment. World J Gastroenterol. 16:2971–2977. 2010. View Article : Google Scholar : PubMed/NCBI

9 

Mok MY, Wong RW and Lau CS: Intestinal pseudo-obstruction in systemic lupus erythematosus: An uncommon but important clinical manifestation. Lupus. 9:11–18. 2000. View Article : Google Scholar : PubMed/NCBI

10 

Garcia López CA, Laredo-Sánchez F, Malagón-Rangel J, Flores-Padilla MG and Nellen-Hummel H: Intestinal pseudo-obstruction in patients with systemic lupus erythematosus: A real diagnostic challenge. World J Gastroenterol. 20:11443–11450. 2014. View Article : Google Scholar : PubMed/NCBI

11 

Khairullah S, Jasmin R, Yahya F, Cheah TE, Ng CT and Sockalingam S: Chronic intestinal pseudo-obstruction: A rare first manifestation of systemic lupus erythematosus. Lupus. 22:957–960. 2013. View Article : Google Scholar : PubMed/NCBI

12 

Ahn E, Luk A, Chetty R and Butany J: Vasculitides of the gastrointestinal tract. Semin Diagn Pathol. 26:77–88. 2009. View Article : Google Scholar : PubMed/NCBI

13 

Huang DF and Chen WS: Images in clinical medicine. Lupus-associated intestinal vasculitis. N Engl J Med. 361:e32009. View Article : Google Scholar : PubMed/NCBI

14 

Lee CK, Ahn MS, Lee EY, Shin JH, Cho YS, Ha HK, Yoo B and Moon HB: Acute abdominal pain in systemic lupus erythematosus: Focus on lupus enteritis (gastrointestinal vasculitis). Ann Rheum Dis. 61:547–550. 2002. View Article : Google Scholar : PubMed/NCBI

15 

Lian TY, Edwards CJ, Chan SP and Chng HH: Reversible acute gastrointestinal syndrome associated with active systemic lupus erythematosus in patients admitted to hospital. Lupus. 12:612–616. 2003. View Article : Google Scholar : PubMed/NCBI

16 

Passam FH, Diamantis ID, Perisinaki G, Saridaki Z, Kritikos H, Georgopoulos D and Boumpas DT: Intestinal ischemia as the first manifestation of vasculitis. Semin Arthritis Rheum. 34:431–441. 2004. View Article : Google Scholar : PubMed/NCBI

17 

Ju JH, Min JK, Jung CK, et al: Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE. Nat Rev Rheumatol. 5:273–281. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Hsu CL, Chen KY, Yeh PS, et al: Outcome and prognostic factors in critically ill patients with systemic lupus erythematosus: A retrospective study. Crit Care. 9:R177–R183. 2005. View Article : Google Scholar : PubMed/NCBI

19 

Tan TC, Wansaicheon GK and Thong BY: Acute onset of systemic lupus erythematosus with extensive gastrointestinal and genitourinary involvement. Lupus. 21:1240–1243. 2012. View Article : Google Scholar : PubMed/NCBI

20 

Majithia R, Joy G, Liang J and Olden K: Acute abdominal pain in systemic lupis erythematosus. Gastrointest Endosc. 75:1267–1268. 2012. View Article : Google Scholar : PubMed/NCBI

21 

Lee J, Jung HS, Nam HC, Kwok SK, Ju JH, Park KS, Kim HY and Park SH: Fulminant amoebic colitis mimicking intestinal vasculitis in a patient with systemic lupus erythematosus. Lupus. 21:1351–1355. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Kishimoto M, Nasir A, Mor A and Belmont HM: Acute gastrointestinal distress syndrome in patients with systemic lupus erythematosus. Lupus. 16:137–141. 2007. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Gu Y, Zhu T, Wang Y and Xu H: Systemic lupus erythematosus with intestinal perforation: A case report. Exp Ther Med 10: 1234-1238, 2015.
APA
Gu, Y., Zhu, T., Wang, Y., & Xu, H. (2015). Systemic lupus erythematosus with intestinal perforation: A case report. Experimental and Therapeutic Medicine, 10, 1234-1238. https://doi.org/10.3892/etm.2015.2639
MLA
Gu, Y., Zhu, T., Wang, Y., Xu, H."Systemic lupus erythematosus with intestinal perforation: A case report". Experimental and Therapeutic Medicine 10.3 (2015): 1234-1238.
Chicago
Gu, Y., Zhu, T., Wang, Y., Xu, H."Systemic lupus erythematosus with intestinal perforation: A case report". Experimental and Therapeutic Medicine 10, no. 3 (2015): 1234-1238. https://doi.org/10.3892/etm.2015.2639
Copy and paste a formatted citation
x
Spandidos Publications style
Gu Y, Zhu T, Wang Y and Xu H: Systemic lupus erythematosus with intestinal perforation: A case report. Exp Ther Med 10: 1234-1238, 2015.
APA
Gu, Y., Zhu, T., Wang, Y., & Xu, H. (2015). Systemic lupus erythematosus with intestinal perforation: A case report. Experimental and Therapeutic Medicine, 10, 1234-1238. https://doi.org/10.3892/etm.2015.2639
MLA
Gu, Y., Zhu, T., Wang, Y., Xu, H."Systemic lupus erythematosus with intestinal perforation: A case report". Experimental and Therapeutic Medicine 10.3 (2015): 1234-1238.
Chicago
Gu, Y., Zhu, T., Wang, Y., Xu, H."Systemic lupus erythematosus with intestinal perforation: A case report". Experimental and Therapeutic Medicine 10, no. 3 (2015): 1234-1238. https://doi.org/10.3892/etm.2015.2639
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