Relapse of choroidal neovascularization in Bietti's crystalline retinopathy following anti‑vascular endothelial growth factor therapy: A case report

Hua,Rui; Chen,Kang; Hu,Yuedong; Wang,Xinling; Chen,Lei

doi:10.3892/etm.2015.2716

Relapse of choroidal neovascularization in Bietti's crystalline retinopathy following anti‑vascular endothelial growth factor therapy: A case report

Authors:
- Rui Hua
- Kang Chen
- Yuedong Hu
- Xinling Wang
- Lei Chen
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Affiliations: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China, Department of Ophthalmology, Fourth Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China
Published online on: September 1, 2015 https://doi.org/10.3892/etm.2015.2716
Pages: 1704-1706
Copyright: © Hua et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Choroidal neovascularization secondary to retinitis pigmentosa is rarely observed in clinical practice. The present study describes a case of atypical retinitis pigmentosa, crystalline retinal pigmentary degeneration, complicated by choroidal neovascularization (CNV) in a 26‑year‑old man presenting with blurred vision in the right eye. Heidelberg multimodality imaging was performed to achieve a confirmed diagnosis. Bevacizumab was injected once intravitreally. The 3‑month follow‑up included visualization of the lesion's regression with spectral domain optical coherence tomography (SD‑OCT). However, at 3 months after the injection, the CNV reoccurred. To the best of our knowledge, this is the first time that a case of CNV secondary to retinitis pigmentosa, in which the diagnosis was confirmed via multimodality imaging and the therapeutic efficacy was evaluated by SD‑OCT, has been reported in China.

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