Concurrence of Fahr's disease and brain tumor: A case report and review of the literature

Lin,Qingtang; Piao,Yueshan; Ling,Feng; Xu,Geng

doi:10.3892/etm.2015.2761

November-2015 Volume 10 Issue 5

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November-2015 Volume 10 Issue 5

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Case Report

Concurrence of Fahr's disease and brain tumor: A case report and review of the literature

Authors:
- Qingtang Lin
- Yueshan Piao
- Feng Ling
- Geng Xu
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100054, P.R. China, Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing 100054, P.R. China
Pages: 1915-1917
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Published online on: September 22, 2015

https://doi.org/10.3892/etm.2015.2761
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Abstract

Fahr's disease is a rare entity characterized by abnormal calcification in the bilateral basal ganglion regions and cerebellum. Concurrence of Fahr's disease with brain tumor is associated with an even lower incidence; the present study describes the fifth such case, in which a 32‑year‑old female presented with a 1‑month history of headache and unsteady walking. Pathology and imaging studies resulted in a diagnosis of low‑grade astrocytoma with calcified deposition. The patient recovered uneventfully. Following a review of the literature, several similarities among the reported cases were revealed. Patients were relatively young at the onset of the disease. The pathological diagnosis for all brain tumors was astrocytoma. The cerebellum was the predominant location of the brain tumor. The imaging studies of these cerebral astrocytomas were almost identical, with a cystic glioma occurring adjacent to a neighboring calcified dentate nucleus. Furthermore, the development of astrocytoma in the bilateral cerebellar hemisphere was not uncommon, which warrants close follow‑up for these patients.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Concurrence of Fahr's disease and brain tumor: A case report and review of the literature

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