Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report

  • Authors:
    • Kenichi Makabe
    • Koichi Kurishima
    • Toshihiro Shiozawa
    • Kunihiko Miyazaki
    • Gen Ohara
    • Katsunori Kagohashi
    • Hiroaki Satoh
    • Nobuyuki Hizawa
  • View Affiliations

  • Published online on: November 25, 2015     https://doi.org/10.3892/etm.2015.2893
  • Pages: 239-242
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The occurrence of ocular metastasis from lung cancer is uncommon. The present study reports the case of a 69-year-old female patient with lung adenocarcinoma who was found to have a metastatic lesion in the left choroid at the time of presentation. As the patient was found to have a mutation in the epidermal growth factor receptor, treatment with gefitinib was administered; however, the response was evaluated as a progressive disease. Thereafter, the patient received chemotherapy with carboplatin, pemetrexed and bevacizumab. Radiological imaging revealed shrinkage of the primary lesion and choroidal metastasis, and the visual power of the left eye was also shown to improve. Therefore, the present case report demonstrated the efficacy and safety of systemic bevacizumab therapy in combination with a platinum doublet for the treatment of choroid metastasis, with morphological and functional improvements observed with regard to the choroidal metastatic tumor.
View Figures
View References

Related Articles

Journal Cover

January-2016
Volume 11 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Makabe K, Kurishima K, Shiozawa T, Miyazaki K, Ohara G, Kagohashi K, Satoh H and Hizawa N: Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report. Exp Ther Med 11: 239-242, 2016
APA
Makabe, K., Kurishima, K., Shiozawa, T., Miyazaki, K., Ohara, G., Kagohashi, K. ... Hizawa, N. (2016). Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report. Experimental and Therapeutic Medicine, 11, 239-242. https://doi.org/10.3892/etm.2015.2893
MLA
Makabe, K., Kurishima, K., Shiozawa, T., Miyazaki, K., Ohara, G., Kagohashi, K., Satoh, H., Hizawa, N."Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report". Experimental and Therapeutic Medicine 11.1 (2016): 239-242.
Chicago
Makabe, K., Kurishima, K., Shiozawa, T., Miyazaki, K., Ohara, G., Kagohashi, K., Satoh, H., Hizawa, N."Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report". Experimental and Therapeutic Medicine 11, no. 1 (2016): 239-242. https://doi.org/10.3892/etm.2015.2893