Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report

Makabe,Kenichi; Kurishima,Koichi; Shiozawa,Toshihiro; Miyazaki,Kunihiko; Ohara,Gen; Kagohashi,Katsunori; Satoh,Hiroaki; Hizawa,Nobuyuki

doi:10.3892/etm.2015.2893

January-2016 Volume 11 Issue 1

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January-2016 Volume 11 Issue 1

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Case Report

Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report

Authors:
- Kenichi Makabe
- Koichi Kurishima
- Toshihiro Shiozawa
- Kunihiko Miyazaki
- Gen Ohara
- Katsunori Kagohashi
- Hiroaki Satoh
- Nobuyuki Hizawa
View Affiliations / Copyright

Affiliations: Division of Ophthalmology, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan, Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan, Division of Respiratory Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan
Pages: 239-242
|
Published online on: November 25, 2015

https://doi.org/10.3892/etm.2015.2893
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Abstract

The occurrence of ocular metastasis from lung cancer is uncommon. The present study reports the case of a 69-year-old female patient with lung adenocarcinoma who was found to have a metastatic lesion in the left choroid at the time of presentation. As the patient was found to have a mutation in the epidermal growth factor receptor, treatment with gefitinib was administered; however, the response was evaluated as a progressive disease. Thereafter, the patient received chemotherapy with carboplatin, pemetrexed and bevacizumab. Radiological imaging revealed shrinkage of the primary lesion and choroidal metastasis, and the visual power of the left eye was also shown to improve. Therefore, the present case report demonstrated the efficacy and safety of systemic bevacizumab therapy in combination with a platinum doublet for the treatment of choroid metastasis, with morphological and functional improvements observed with regard to the choroidal metastatic tumor.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report

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Abstract

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