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Clinical and radiographic observations from four patients with primary hepatic lymphoma

  • Authors:
    • Hui‑Juan Hu
    • Yan‑Juan Qu
    • Zhi‑Xiong Tian
    • Zai‑Peng Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Computed Tomography, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China
    Copyright: © Hu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 381-386
    |
    Published online on: December 16, 2015
       https://doi.org/10.3892/etm.2015.2940
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Abstract

The aim of the present study was to delineate the radiographic and clinical features of primary hepatic lymphoma (PHL). Four histopathologically confirmed cases of PHL were analyzed with respect to the radiological, clinical and pathological characteristics. The main clinical manifestations included upper right quadrant pain and lymphoma‑associated B symptoms, such as fever, night sweating and weight loss. All the patients had elevated serum levels of lactate dehydrogenase. Furthermore, all the patients underwent plain and enhanced computed tomography examinations, which identified low‑density lesions without marked enhancement. Solitary masses were observed in two cases, while multiple focal lesions were noted in one case and diffuse multi‑speckled nodules were observed in one case. Two patients underwent abdominal magnetic resonance imaging, which revealed lesions that were hyperintense on T1‑weighted imaging (WI) scans and hypointense on T2WI scans, and exhibited slight to moderate enhancement with a dynamic contrast‑enhanced protocol. In one case, vessels were visible within the lesion. Therefore, the present study concluded that PHL is a rare condition that exhibits non‑specific clinical and radiological features. A combination of imaging results and clinical manifestations can be used to facilitate a diagnosis of PHL.
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1 

Agmon-Levin N, Berger I, Shtalrid M, Schlanger H and Sthoeger ZM: Primary hepatic lymphoma, a case report and review of the literature. Age Ageing. 33:637–640. 2004. View Article : Google Scholar : PubMed/NCBI

2 

Yu YD, Kim DS, Byun GY, et al: Primary hepatic marginal zone B cell lymphoma: A case report and review of the literature. Indian J Surg. 75(Suppl 1): 331–336. 2013. View Article : Google Scholar : PubMed/NCBI

3 

Yang XW, Tan WF, Yu WL, Shi S, Wang Y, Zhang YL, Zhang YJ and Wu MC: Diagnosis and surgical treatment of primary hepatic lymphoma. World J Gastroenterol. 16:6016–6019. 2010.PubMed/NCBI

4 

Noronha V, Shafi NQ, Obando JA and Kummar S: Primary non-Hodgkin's lymphoma of the liver. Crit Rev Oncol Hematol. 53:199–207. 2005. View Article : Google Scholar : PubMed/NCBI

5 

Caccamo D, Pervez NK and Marchevsky A: Primary lymphoma of the liver in the acquired immunodeficiency syndrome. Arch Pathol Lab Med. 110:553–555. 1986.PubMed/NCBI

6 

Cameron AM, Truty J, Truell J, et al: Fulminant hepatic failure from primary hepatic lymphoma: successful treatment with orthotopic liver transplantation and chemotherapy. Transplantation. 80:993–996. 2005. View Article : Google Scholar : PubMed/NCBI

7 

Elsayes KM, Menias CO, Willatt JM, Pandya A, Wiggins M and Platt J: Primary hepatic lymphoma, imaging findings. J Med Imaging Radiat Oncol. 53:373–379. 2009. View Article : Google Scholar : PubMed/NCBI

8 

Gomyo H, Kagami Y, Kato H, et al: Primary hepatic follicular lymphoma: a case report and discussion of chemotherapy and favorable outcomes. J Clin Exp Hematop. 47:73–77. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Takeuchi N and Naba K: Primary hepatic lymphoma is difficult to discriminate from a liver abscess. Case Rep Gastrointest Med. 2014:9253072014.PubMed/NCBI

10 

Page RD, Romaguera JE, Osborne B, et al: Primary hepatic lymphoma: favorable outcome after combination chemotherapy. Cancer. 92:2023–2029. 2001. View Article : Google Scholar : PubMed/NCBI

11 

Bronowicki JP, Bineau C, Feugier P, et al: Primary lymphoma of the liver: clinical pathological features and relationship with HCV infection in French patients. Hepatology. 37:781–787. 2003. View Article : Google Scholar : PubMed/NCBI

12 

Aozasa K, Mishima K and Ohsawa M: Primary malignant lymphoma of the liver. Leuk Lymphoma. 10:353–357. 1993. View Article : Google Scholar : PubMed/NCBI

13 

Santos ES, Raez LE, Salvatierra J, Morgensztern D, Shanmugan N and Neff GW: Primary hepatic non-Hodgkin's lymphomas, case report and review of the literature. Am J Gastroenterol. 98:2789–2793. 2003. View Article : Google Scholar : PubMed/NCBI

14 

Masood A, Kairouz S, Hudhud KH, Hegazi AZ, Banu A and Gupta NC: Primary non-Hodgkin lymphoma of liver. Curr Oncol. 16:74–77. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Haider FS, Smith R, Khan S and Rahman O: Primary hepatic lymphoma presenting as fulminant hepatic failure with hyperferritinemia, a case report. J Med Case Reports. 2:2792008. View Article : Google Scholar

16 

Lei KI: Primary non-Hodgkin's lymphoma of the liver. Leuk Lymphoma. 29:293–299. 1998. View Article : Google Scholar : PubMed/NCBI

17 

Avlonitis VS and Linos D: Primary hepatic lymphoma: a review. Eur J Surg. 165:725–729. 1999. View Article : Google Scholar : PubMed/NCBI

18 

Levy AD: Malignant liver tumors. Clin Liver Dis. 6:147–164. 2002. View Article : Google Scholar : PubMed/NCBI

19 

Cerban R, Gheorghe L, Becheanu G, Serban V and Gheorghe C: Primary focal T-cell lymphoma of the liver, a case report and review of the literature. J Gastrointestin Liver Dis. 21:213–216. 2012.PubMed/NCBI

20 

Maher MM, McDermott SR, Fenlon HM, et al: Imaging of primary non-Hodgkin's lymphoma of the liver. Clin Radiol. 56:295–301. 2001. View Article : Google Scholar : PubMed/NCBI

21 

Hussain SM, Semelka RC and Mitchell DG: MR imaging of hepatocellular carcinoma. Magn Reson Imaging Clin N Am. 10:31–52. 2002. View Article : Google Scholar : PubMed/NCBI

22 

Mortelé KJ, Praet M, Van Vlierberghe H, Kunnen M and Ros PR: CT and MR imaging findings in focal nodular hyperplasia of the liver, radiologic-pathologic correlation. AJR Am J Roentgenol. 175:687–692. 2000. View Article : Google Scholar : PubMed/NCBI

23 

Terkivatan T, van den Bos IC, Hussain SM, Wielopolski PA, de Man RAI and Jzermans JN: Focal nodular hyperplasia: lesion characteristics on state-of-the-art MRI including dynamic gadolinium- enhanced and superparamagnetic iron-oxide-uptake sequences in a prospective study. J Magn Reson Imaging. 24:864–872. 2006. View Article : Google Scholar : PubMed/NCBI

24 

Hussain SM, Terkivatan T, Zondervan PE, Lanjouw E, de Rave S, Ijzermans JN and de Man RA: Focal nodular, hyperplasia, findings at state-of-the-art MR imaging, US, CT and pathologic analysis. Radiographics. 24:3–19. 2004. View Article : Google Scholar : PubMed/NCBI

25 

Blachar A, Federle MP, Ferris JV, et al: Radiologists' performance in the diagnosis of liver tumors with central scars by using specific CT criteria. Radiology. 223:532–539. 2002. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Hu HJ, Qu YJ, Tian ZX and Zhang ZP: Clinical and radiographic observations from four patients with primary hepatic lymphoma. Exp Ther Med 11: 381-386, 2016.
APA
Hu, H., Qu, Y., Tian, Z., & Zhang, Z. (2016). Clinical and radiographic observations from four patients with primary hepatic lymphoma. Experimental and Therapeutic Medicine, 11, 381-386. https://doi.org/10.3892/etm.2015.2940
MLA
Hu, H., Qu, Y., Tian, Z., Zhang, Z."Clinical and radiographic observations from four patients with primary hepatic lymphoma". Experimental and Therapeutic Medicine 11.2 (2016): 381-386.
Chicago
Hu, H., Qu, Y., Tian, Z., Zhang, Z."Clinical and radiographic observations from four patients with primary hepatic lymphoma". Experimental and Therapeutic Medicine 11, no. 2 (2016): 381-386. https://doi.org/10.3892/etm.2015.2940
Copy and paste a formatted citation
x
Spandidos Publications style
Hu HJ, Qu YJ, Tian ZX and Zhang ZP: Clinical and radiographic observations from four patients with primary hepatic lymphoma. Exp Ther Med 11: 381-386, 2016.
APA
Hu, H., Qu, Y., Tian, Z., & Zhang, Z. (2016). Clinical and radiographic observations from four patients with primary hepatic lymphoma. Experimental and Therapeutic Medicine, 11, 381-386. https://doi.org/10.3892/etm.2015.2940
MLA
Hu, H., Qu, Y., Tian, Z., Zhang, Z."Clinical and radiographic observations from four patients with primary hepatic lymphoma". Experimental and Therapeutic Medicine 11.2 (2016): 381-386.
Chicago
Hu, H., Qu, Y., Tian, Z., Zhang, Z."Clinical and radiographic observations from four patients with primary hepatic lymphoma". Experimental and Therapeutic Medicine 11, no. 2 (2016): 381-386. https://doi.org/10.3892/etm.2015.2940
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