Selective laser trabeculoplasty in treating post‑trabeculectomy advanced primary open‑angle glaucoma

Zhang,Hongyang; Yang,Yangfan; Xu,Jiangang; Yu,Minbin

doi:10.3892/etm.2015.2959

Selective laser trabeculoplasty in treating post‑trabeculectomy advanced primary open‑angle glaucoma

Authors:
- Hongyang Zhang
- Yangfan Yang
- Jiangang Xu
- Minbin Yu
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Affiliations: Department of Ophthalmology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510086, P.R. China, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‑sen University, Guangzhou, Guangdong 510060, P.R. China
Published online on: December 29, 2015 https://doi.org/10.3892/etm.2015.2959
Pages: 1090-1094

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Abstract

The aim of this study was to investigate the safety and efficacy of selective laser trabeculoplasty (SLT) treatment of patients with primary open‑angle glaucoma (POAG) who could not obtain target intraocular pressure (IOP) through post‑trabeculectomy medication. Sixteen patients with POAG (18 eyes), who could not obtain target IOP following medication and surgery, were treated with 360˚ SLT. The IOP, anterior chamber inflammation, and daytime and long‑term IOP fluctuations before and 2 h, 1 day, 7 days, 1 month, 3 months, 6 months and 9 months after SLT were documented. The IOP following the laser treatment was reduced by >20% compared with the baseline IOP prior to the treatment. Prior to SLT, the patients were administered different types (average, 2.8±0.8) of anti‑glaucoma drugs and had an average IOP of 21.3±3.4 mmHg. Following SLT, the average IOP decreased to 16.2±3.0 mmHg and the success rate was 77.7%. The pre‑SLT daytime IOP fluctuation was 4.1±1.4 mmHg, which decreased to 2.6±1.1 mmHg following the laser treatment (P<0.05). In conclusion, this study demonstrated that SLT could reduce the IOP in post‑trabeculectomy patients with POAG, and reduce the daytime IOP fluctuations.

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