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Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus

  • Authors:
    • Pin Zhang
    • Hongwei Zhang
    • Xiaodong Han
    • Jianzhong Di
    • Yulong Zhou
    • Kun Li
    • Qi Zheng
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, The Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 827-831
    |
    Published online on: January 11, 2016
       https://doi.org/10.3892/etm.2016.2973
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Abstract

Gastric bypass may be conducted to aid in glycemic control in adults with type 2 diabetes mellitus (T2DM). The aim of the present study was to investigate the clinical results of diabetes remission and metabolic syndrome in individuals with T2DM after undergoing a gastric bypass. A total of 85 patients (39 men and 46 women) with T2DM underwent laparoscopic Roux‑en‑Y gastric bypass (LRYGB). Data regarding patient demographics, body mass index (BMI), co‑morbidities and details of diabetes mellitus, including disease duration, remission, β‑cell function, blood lipid levels and nutritive status were prospectively collected and analyzed. The mean duration from the onset of T2DM was 7.79±4.84 years (range, 1 month to 22 years). The preoperative mean BMI was 31.60±4.10 (range, 28.53‑48.10 kg/m2), mean percentage of body fat was 36.35±9.12% (range, 18‑56%), and the mean HbA1c was 8.32±2.13% (range, 7‑15.9%). Five patients (5.9%) developed complications without mortality. T2DM and β‑cell function were significantly improved from by month 6 after surgery (P<0.05). Improvements in central obesity, blood pressure (BP; systolic and diastolic) control, blood lipid levels were observed, without malnutrition or severe anemia. Therefore, the present results indicate that laparoscopic RYGBP is a safe and effective procedure for improving glycemic control, obesity, body fat percentage and BP in patients with T2DM and obesity.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang P, Zhang H, Han X, Di J, Zhou Y, Li K and Zheng Q: Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus. Exp Ther Med 11: 827-831, 2016.
APA
Zhang, P., Zhang, H., Han, X., Di, J., Zhou, Y., Li, K., & Zheng, Q. (2016). Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus. Experimental and Therapeutic Medicine, 11, 827-831. https://doi.org/10.3892/etm.2016.2973
MLA
Zhang, P., Zhang, H., Han, X., Di, J., Zhou, Y., Li, K., Zheng, Q."Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus". Experimental and Therapeutic Medicine 11.3 (2016): 827-831.
Chicago
Zhang, P., Zhang, H., Han, X., Di, J., Zhou, Y., Li, K., Zheng, Q."Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus". Experimental and Therapeutic Medicine 11, no. 3 (2016): 827-831. https://doi.org/10.3892/etm.2016.2973
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang P, Zhang H, Han X, Di J, Zhou Y, Li K and Zheng Q: Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus. Exp Ther Med 11: 827-831, 2016.
APA
Zhang, P., Zhang, H., Han, X., Di, J., Zhou, Y., Li, K., & Zheng, Q. (2016). Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus. Experimental and Therapeutic Medicine, 11, 827-831. https://doi.org/10.3892/etm.2016.2973
MLA
Zhang, P., Zhang, H., Han, X., Di, J., Zhou, Y., Li, K., Zheng, Q."Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus". Experimental and Therapeutic Medicine 11.3 (2016): 827-831.
Chicago
Zhang, P., Zhang, H., Han, X., Di, J., Zhou, Y., Li, K., Zheng, Q."Effectiveness and safety of laparoscopic Roux-en-Y gastric bypass for the treatment of type 2 diabetes mellitus". Experimental and Therapeutic Medicine 11, no. 3 (2016): 827-831. https://doi.org/10.3892/etm.2016.2973
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