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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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April-2016 Volume 11 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Case Report Open Access

Multifocal skeletal tuberculosis: A case report

  • Authors:
    • Liang Zhang
    • Jingcheng Wang
    • Xinmin Feng
    • Yuping Tao
    • Jiandong Yang
    • Shenfei Zhang
    • Jun Cai
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu, Yangzhou, Jiangsu 225001, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1288-1292
    |
    Published online on: January 29, 2016
       https://doi.org/10.3892/etm.2016.3032
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Abstract

Tuberculosis (TB) of the musculoskeletal system is a rare clinical condition. Multifocal bone involvement is extremely rare and difficult to recognize. Thus, due to the diverse and atypical clinical manifestations of multifocal skeletal TB, the disease is easy to misdiagnose. In the present study, a rare case of atypical disseminated multifocal skeletal TB was reported, which exhibited uncommon findings in radiological images that were more suggestive of a hematological malignancy or metastatic disease. In conclusion, the diagnosis of this condition by conventional diagnostic methods is challenging. The importance of CT‑guided needle biopsy and open biopsy in the diagnosis of skeletal TB was emphasized.
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1 

Dye C, Scheele S, Dolin P, Pathania V and Raviglione MC: Consensus statement. Global burden of tuberculosis: Estimated incidence, prevalence and mortality by country. WHO global surveillance and monitoring project. JAMA. 282:677–686. 1999. View Article : Google Scholar : PubMed/NCBI

2 

Moon MS, Moon YW, Moon JL, Kim SS and Sun DH: Conservative treatment of tuberculosis of the lumbar and lumbosacral spine. Clin Orthop Relat Res. 40–49. 2002. View Article : Google Scholar : PubMed/NCBI

3 

Yilmaz MH, Kantarci F, Mihmanli I and Kanberoglu K: Multifocal skeletal tuberculosis. South Med J. 97:785–787. 2004. View Article : Google Scholar : PubMed/NCBI

4 

Agarwal A, Khan SA and Qureshi NA: Multifocal osteoarticular tuberculosis in children. J Orthop Surg (Hong Kong). 19:336–340. 2011.PubMed/NCBI

5 

Hong L, Wu JG, Ding JG, Wang XY, Zheng MH, Fu RQ, Li WB, Peng WX, He WF and Sun QF: Multifocal skeletal tuberculosis: Experience in diagnosis and treatment. Med Mal Infect. 40:6–11. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Marudanayagam A and Gnanadoss JJ: Multifocal skeletal tuberculosis: A report of three cases. Iowa Orthop J. 26:151–153. 2006.PubMed/NCBI

7 

Danchaivijitr N, Temram S, Thepmongkhol K and Chiewvit P: Diagnostic accuracy of MR imaging in tuberculous spondylitis. J Med Assoc Thai. 90:1581–1589. 2007.PubMed/NCBI

8 

Wright GD and Sutherland AD: New strategies for combating multidrug-resistant bacteria. Trends Mol Med. 13:260–267. 2007. View Article : Google Scholar : PubMed/NCBI

9 

Zhang Y, Zhang Y and Ma J: The prospect of incidental detection of unsuspected skeletal tuberculosis by bone scintigraphy should not be overlooked. Clin Nucl Med. 32:435–439. 2007. View Article : Google Scholar : PubMed/NCBI

10 

St Clair Strange FG: Current concepts review. Tuberculosis of bones and joints (78-A:288-298, Feb. 1996) by Watts and Lifeso. J Bone Joint Surg Am. 80:6041998.PubMed/NCBI

11 

Moore SL and Rafii M: Imaging of musculoskeletal and spinal tuberculosis. Radiol Clin North Am. 39:329–342. 2001. View Article : Google Scholar : PubMed/NCBI

12 

Ringshausen FC, Tannapfel A, Nicolas V, Weber A, Duchna HW, Schultze-Werninghaus G and Rohde G: A fatal case of spinal tuberculosis mistaken for metastatic lung cancer: Recalling ancient Pott's disease. Ann Clin Microbiol Antimicrob. 8:322009. View Article : Google Scholar : PubMed/NCBI

13 

Ballah D, Nijs E, Keller MS, Zhu X, Krishnamurthy G and Cahill AM: Percutaneous CT-guided vertebral bone biopsy in children. Pediatr Radiol. 43:582–588. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Poyanli O, Akan K, Unay K and Tangay C: CT-guided percutaneous transpedicular biopsy for the diagnosis of vertebral lesions. Acta Orthop Belg. 74:503–506. 2008.PubMed/NCBI

15 

Hao DJ, Sun HH, He BR, Liu TJ, Jiang YH and Zhao QP: Accuracy of CT-guided biopsies in 158 patients with thoracic spinal lesions. Acta Radiol. 52:1015–1019. 2011. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang L, Wang J, Feng X, Tao Y, Yang J, Zhang S and Cai J: Multifocal skeletal tuberculosis: A case report. Exp Ther Med 11: 1288-1292, 2016.
APA
Zhang, L., Wang, J., Feng, X., Tao, Y., Yang, J., Zhang, S., & Cai, J. (2016). Multifocal skeletal tuberculosis: A case report. Experimental and Therapeutic Medicine, 11, 1288-1292. https://doi.org/10.3892/etm.2016.3032
MLA
Zhang, L., Wang, J., Feng, X., Tao, Y., Yang, J., Zhang, S., Cai, J."Multifocal skeletal tuberculosis: A case report". Experimental and Therapeutic Medicine 11.4 (2016): 1288-1292.
Chicago
Zhang, L., Wang, J., Feng, X., Tao, Y., Yang, J., Zhang, S., Cai, J."Multifocal skeletal tuberculosis: A case report". Experimental and Therapeutic Medicine 11, no. 4 (2016): 1288-1292. https://doi.org/10.3892/etm.2016.3032
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang L, Wang J, Feng X, Tao Y, Yang J, Zhang S and Cai J: Multifocal skeletal tuberculosis: A case report. Exp Ther Med 11: 1288-1292, 2016.
APA
Zhang, L., Wang, J., Feng, X., Tao, Y., Yang, J., Zhang, S., & Cai, J. (2016). Multifocal skeletal tuberculosis: A case report. Experimental and Therapeutic Medicine, 11, 1288-1292. https://doi.org/10.3892/etm.2016.3032
MLA
Zhang, L., Wang, J., Feng, X., Tao, Y., Yang, J., Zhang, S., Cai, J."Multifocal skeletal tuberculosis: A case report". Experimental and Therapeutic Medicine 11.4 (2016): 1288-1292.
Chicago
Zhang, L., Wang, J., Feng, X., Tao, Y., Yang, J., Zhang, S., Cai, J."Multifocal skeletal tuberculosis: A case report". Experimental and Therapeutic Medicine 11, no. 4 (2016): 1288-1292. https://doi.org/10.3892/etm.2016.3032
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