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Article

Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up

  • Authors:
    • Li‑Shou Xiong
    • Ying‑Ying Gong
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Geriatrics, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China
  • Pages: 2462-2466
    |
    Published online on: March 23, 2016
       https://doi.org/10.3892/etm.2016.3181
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Abstract

Ménétrier's disease (MD) is a rare disease characterized by markedly hypertrophied gastric mucosal folds typically associated with hypoalbuminemia and anemia. However, the natural history of MD in adults remains unclear and is rarely reported in the literature. The current study presents a case of MD with a 9‑year follow‑up. A 56‑year‑old man was diagnosed with MD in 2005. The patient was followed up and underwent surveillance endoscopy once or twice each year. In the present case, the anemia and hypoproteinemia were eliminated following red blood cell transfusion and intravenous iron therapies. The symptoms were relieved after 4 years. Treatment with octreotide had little effect on the gastric mucosa, while antimicrobial combination therapy provided no benefit in the present H. pylori‑negative case of MD. In addition, despite abnormalities of the gastric mucosa in the patient persisting after 9 years of follow-up with no evidence of malignancy, malignant transformation in MD should not be overlooked, and regular monitoring of the gastric mucosa via endoscopy is necessary.
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Copy and paste a formatted citation
Spandidos Publications style
Xiong LS and Gong YY: Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up. Exp Ther Med 11: 2462-2466, 2016.
APA
Xiong, L., & Gong, Y. (2016). Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up. Experimental and Therapeutic Medicine, 11, 2462-2466. https://doi.org/10.3892/etm.2016.3181
MLA
Xiong, L., Gong, Y."Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up". Experimental and Therapeutic Medicine 11.6 (2016): 2462-2466.
Chicago
Xiong, L., Gong, Y."Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up". Experimental and Therapeutic Medicine 11, no. 6 (2016): 2462-2466. https://doi.org/10.3892/etm.2016.3181
Copy and paste a formatted citation
x
Spandidos Publications style
Xiong LS and Gong YY: Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up. Exp Ther Med 11: 2462-2466, 2016.
APA
Xiong, L., & Gong, Y. (2016). Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up. Experimental and Therapeutic Medicine, 11, 2462-2466. https://doi.org/10.3892/etm.2016.3181
MLA
Xiong, L., Gong, Y."Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up". Experimental and Therapeutic Medicine 11.6 (2016): 2462-2466.
Chicago
Xiong, L., Gong, Y."Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up". Experimental and Therapeutic Medicine 11, no. 6 (2016): 2462-2466. https://doi.org/10.3892/etm.2016.3181
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