Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up

  • Authors:
    • Li‑Shou Xiong
    • Ying‑Ying Gong
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  • Published online on: March 23, 2016     https://doi.org/10.3892/etm.2016.3181
  • Pages: 2462-2466
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Abstract

Ménétrier's disease (MD) is a rare disease characterized by markedly hypertrophied gastric mucosal folds typically associated with hypoalbuminemia and anemia. However, the natural history of MD in adults remains unclear and is rarely reported in the literature. The current study presents a case of MD with a 9‑year follow‑up. A 56‑year‑old man was diagnosed with MD in 2005. The patient was followed up and underwent surveillance endoscopy once or twice each year. In the present case, the anemia and hypoproteinemia were eliminated following red blood cell transfusion and intravenous iron therapies. The symptoms were relieved after 4 years. Treatment with octreotide had little effect on the gastric mucosa, while antimicrobial combination therapy provided no benefit in the present H. pylori‑negative case of MD. In addition, despite abnormalities of the gastric mucosa in the patient persisting after 9 years of follow-up with no evidence of malignancy, malignant transformation in MD should not be overlooked, and regular monitoring of the gastric mucosa via endoscopy is necessary.
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June-2016
Volume 11 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Xiong LS and Xiong LS: Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up. Exp Ther Med 11: 2462-2466, 2016
APA
Xiong, L., & Xiong, L. (2016). Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up. Experimental and Therapeutic Medicine, 11, 2462-2466. https://doi.org/10.3892/etm.2016.3181
MLA
Xiong, L., Gong, Y."Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up". Experimental and Therapeutic Medicine 11.6 (2016): 2462-2466.
Chicago
Xiong, L., Gong, Y."Natural history of adult-onset Ménétrier's disease: Report of a case with 9-year follow-up". Experimental and Therapeutic Medicine 11, no. 6 (2016): 2462-2466. https://doi.org/10.3892/etm.2016.3181