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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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July-2016 Volume 12 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

  • Authors:
    • Yi‑Wei Zhang
    • Ji‑Hua Zhong
    • Xiao‑Long Chen
    • Fei Xiao
    • Fang‑Yuan Chen
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P.R. China
  • Pages: 319-322
    |
    Published online on: April 15, 2016
       https://doi.org/10.3892/etm.2016.3259
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Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive tumor, which frequently presents as cutaneous lesions and subsequently progresses to bone marrow (BM) involvement and leukemic dissemination. BPDCN is a rare entity that belongs in the same class as acute myeloid leukemia‑associated precursor neoplasms, according to the 2008 World Health Organization classification. The present study reported the case of a 26‑year‑old female who presented with evident thrombocytopenia, leukocytosis and anemia, but without skin lesions. The results of peripheral blood, BM smear and BM biopsy examinations detected numerous blastic or abnormal cells. In addition, flow cytometric analysis of BM demonstrated the presence of plasmacytoid dendritic cell‑neoplastic precursor cells (CD4+, CD56+, CD123+, CD304+ and human leukocyte antigen‑DR+ phenotype).
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Copy and paste a formatted citation
Spandidos Publications style
Zhang YW, Zhong JH, Chen XL, Xiao F and Chen FY: Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. Exp Ther Med 12: 319-322, 2016.
APA
Zhang, Y., Zhong, J., Chen, X., Xiao, F., & Chen, F. (2016). Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. Experimental and Therapeutic Medicine, 12, 319-322. https://doi.org/10.3892/etm.2016.3259
MLA
Zhang, Y., Zhong, J., Chen, X., Xiao, F., Chen, F."Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review". Experimental and Therapeutic Medicine 12.1 (2016): 319-322.
Chicago
Zhang, Y., Zhong, J., Chen, X., Xiao, F., Chen, F."Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 1 (2016): 319-322. https://doi.org/10.3892/etm.2016.3259
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang YW, Zhong JH, Chen XL, Xiao F and Chen FY: Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. Exp Ther Med 12: 319-322, 2016.
APA
Zhang, Y., Zhong, J., Chen, X., Xiao, F., & Chen, F. (2016). Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review. Experimental and Therapeutic Medicine, 12, 319-322. https://doi.org/10.3892/etm.2016.3259
MLA
Zhang, Y., Zhong, J., Chen, X., Xiao, F., Chen, F."Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review". Experimental and Therapeutic Medicine 12.1 (2016): 319-322.
Chicago
Zhang, Y., Zhong, J., Chen, X., Xiao, F., Chen, F."Blastic plasmacytoid dendritic cell neoplasm: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 1 (2016): 319-322. https://doi.org/10.3892/etm.2016.3259
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