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Case Report

Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report

  • Authors:
    • Hui Wu
    • Yuan Hu
    • Xiao‑Ru Shi
    • Feihong Xu
    • Chun‑Ying Jiang
    • Rong Huang
    • Hui Jia
  • View Affiliations / Copyright

    Affiliations: Department of Ophthalmology, First Affiliated Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA
  • Pages: 343-346
    |
    Published online on: April 27, 2016
       https://doi.org/10.3892/etm.2016.3296
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Abstract

The present report describes the clinical course and treatment of a Mooren‑like ulcer associated with abuse of topical anesthetics and dexamethasone. A 38‑year‑old male physician treated himself with lidocaine, tetracaine and dexamethasone (DEX) eye drops for severe pain and decline of vision in both eyes. After six months of treatment, his right cornea exhibited annular melting with full‑thickness stromal infiltration at the limbus and central corneal haze. His left cornea was completely melted and exhibited iris prolapse. The patient was treated with topical antibiotics, lubricants and underwent a binocular keratoplasty. The surgery was successful and after eight months the postoperative best‑corrected visual acuities were counting fingers in the right eye and light perception in the left eye. In summary, this report documents a severe case of keratopathy presenting as Mooren‑like ulcer caused by topical anesthetics and DEX, which were treated via keratoplasty, resulting in useful vision being retained.
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Copy and paste a formatted citation
Spandidos Publications style
Wu H, Hu Y, Shi XR, Xu F, Jiang CY, Huang R and Jia H: Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report. Exp Ther Med 12: 343-346, 2016.
APA
Wu, H., Hu, Y., Shi, X., Xu, F., Jiang, C., Huang, R., & Jia, H. (2016). Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report. Experimental and Therapeutic Medicine, 12, 343-346. https://doi.org/10.3892/etm.2016.3296
MLA
Wu, H., Hu, Y., Shi, X., Xu, F., Jiang, C., Huang, R., Jia, H."Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report". Experimental and Therapeutic Medicine 12.1 (2016): 343-346.
Chicago
Wu, H., Hu, Y., Shi, X., Xu, F., Jiang, C., Huang, R., Jia, H."Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report". Experimental and Therapeutic Medicine 12, no. 1 (2016): 343-346. https://doi.org/10.3892/etm.2016.3296
Copy and paste a formatted citation
x
Spandidos Publications style
Wu H, Hu Y, Shi XR, Xu F, Jiang CY, Huang R and Jia H: Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report. Exp Ther Med 12: 343-346, 2016.
APA
Wu, H., Hu, Y., Shi, X., Xu, F., Jiang, C., Huang, R., & Jia, H. (2016). Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report. Experimental and Therapeutic Medicine, 12, 343-346. https://doi.org/10.3892/etm.2016.3296
MLA
Wu, H., Hu, Y., Shi, X., Xu, F., Jiang, C., Huang, R., Jia, H."Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report". Experimental and Therapeutic Medicine 12.1 (2016): 343-346.
Chicago
Wu, H., Hu, Y., Shi, X., Xu, F., Jiang, C., Huang, R., Jia, H."Keratopathy due to ophthalmic drug abuse with corneal melting and perforation presenting as Mooren‑like ulcer: A case report". Experimental and Therapeutic Medicine 12, no. 1 (2016): 343-346. https://doi.org/10.3892/etm.2016.3296
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