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Review

Photodynamic therapy as an antifungal treatment (Review)

  • Authors:
    • Yi Liang
    • Li‑Ming Lu
    • Yong Chen
    • You‑Kun Lin
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, Liuzhou Municipal Liutie Central Hospital, Liuzhou, Guangxi 545007, P.R. China, Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China
  • Pages: 23-27
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    Published online on: May 11, 2016
       https://doi.org/10.3892/etm.2016.3336
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Abstract

Photodynamic therapy (PDT) involves the systemic or topical application of a photosensitizer (PS), alongside the selective illumination of the target lesion with light of an appropriate wavelength, in order to promote localized oxidative photodamage and subsequent cell death. Numerous studies have demonstrated that PDT is highly effective in the destruction of fungi in vitro. The mechanism underlying the effects of PDT results from the photons of visible light of an appropriate wavelength interacting with the intracellular molecules of the PS. Reactive species are produced as a result of the oxidative stress caused by the interaction between the visible light and the biological tissue. At present, no antifungal treatment based on PDT has been licensed. However, antifungal PDT is emerging as an area of interest for research.
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Copy and paste a formatted citation
Spandidos Publications style
Liang Y, Lu LM, Chen Y and Lin YK: Photodynamic therapy as an antifungal treatment (Review). Exp Ther Med 12: 23-27, 2016.
APA
Liang, Y., Lu, L., Chen, Y., & Lin, Y. (2016). Photodynamic therapy as an antifungal treatment (Review). Experimental and Therapeutic Medicine, 12, 23-27. https://doi.org/10.3892/etm.2016.3336
MLA
Liang, Y., Lu, L., Chen, Y., Lin, Y."Photodynamic therapy as an antifungal treatment (Review)". Experimental and Therapeutic Medicine 12.1 (2016): 23-27.
Chicago
Liang, Y., Lu, L., Chen, Y., Lin, Y."Photodynamic therapy as an antifungal treatment (Review)". Experimental and Therapeutic Medicine 12, no. 1 (2016): 23-27. https://doi.org/10.3892/etm.2016.3336
Copy and paste a formatted citation
x
Spandidos Publications style
Liang Y, Lu LM, Chen Y and Lin YK: Photodynamic therapy as an antifungal treatment (Review). Exp Ther Med 12: 23-27, 2016.
APA
Liang, Y., Lu, L., Chen, Y., & Lin, Y. (2016). Photodynamic therapy as an antifungal treatment (Review). Experimental and Therapeutic Medicine, 12, 23-27. https://doi.org/10.3892/etm.2016.3336
MLA
Liang, Y., Lu, L., Chen, Y., Lin, Y."Photodynamic therapy as an antifungal treatment (Review)". Experimental and Therapeutic Medicine 12.1 (2016): 23-27.
Chicago
Liang, Y., Lu, L., Chen, Y., Lin, Y."Photodynamic therapy as an antifungal treatment (Review)". Experimental and Therapeutic Medicine 12, no. 1 (2016): 23-27. https://doi.org/10.3892/etm.2016.3336
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