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Review Open Access

Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review)

  • Authors:
    • Dengwei He
    • Weiyang Yu
    • Zhenzhong Chen
    • Liangchen Li
    • Kejun Zhu
    • Shunwu Fan
  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedics, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China, Department of Orthopedics, Lishui Central Hospital, Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China
    Copyright: © He et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 879-882
    |
    Published online on: May 19, 2016
       https://doi.org/10.3892/etm.2016.3369
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Abstract

In this review, we explored the progress of the pathogenesis of Kümmell's disease intravertebral vacuum. Using different expressions of the same disease including ‘Kümmell's disease’, ‘avascular necrosis after vertebral compression fracture (VCF)’, ‘post-traumatic vertebral osteonecrosis’, ‘vertebral pseudarthrosis’, ‘intravertebral vacuum (cleft or gas)’, ‘delayed vertebral collapse’, ‘VCF nonunion’, and by conducting a search of the PubMed database, we analyzed the results to examine the pathogenesis of the intravertebral vacuum of Kümmell's disease after referring to pertinent literature on intravertebral vacuum of ischemic necrosis after VCF, and exploring the progress of pathogenesis of this disease. A number of discrepancies were identified within the pathogenesis of the intravertebral vacuum after VCF. There were statements such as avascular necrosis of the vertebral body, bone biomechanics, gas forming and other types of claims, all of which obtained clinical and biomechanical supporting evidence. Collectively, most of the researchers believe that Kümmell vertebral fracture syndrome was the comprehensive effect of multiple factors including osteoporosis, avascular necrosis of the vertebral body, and biomechanical changes following fracture. However, there are a number of discrepancies to be resolved and future studies are therefore needed.
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Copy and paste a formatted citation
Spandidos Publications style
He D, Yu W, Chen Z, Li L, Zhu K and Fan S: Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review). Exp Ther Med 12: 879-882, 2016.
APA
He, D., Yu, W., Chen, Z., Li, L., Zhu, K., & Fan, S. (2016). Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review). Experimental and Therapeutic Medicine, 12, 879-882. https://doi.org/10.3892/etm.2016.3369
MLA
He, D., Yu, W., Chen, Z., Li, L., Zhu, K., Fan, S."Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review)". Experimental and Therapeutic Medicine 12.2 (2016): 879-882.
Chicago
He, D., Yu, W., Chen, Z., Li, L., Zhu, K., Fan, S."Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review)". Experimental and Therapeutic Medicine 12, no. 2 (2016): 879-882. https://doi.org/10.3892/etm.2016.3369
Copy and paste a formatted citation
x
Spandidos Publications style
He D, Yu W, Chen Z, Li L, Zhu K and Fan S: Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review). Exp Ther Med 12: 879-882, 2016.
APA
He, D., Yu, W., Chen, Z., Li, L., Zhu, K., & Fan, S. (2016). Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review). Experimental and Therapeutic Medicine, 12, 879-882. https://doi.org/10.3892/etm.2016.3369
MLA
He, D., Yu, W., Chen, Z., Li, L., Zhu, K., Fan, S."Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review)". Experimental and Therapeutic Medicine 12.2 (2016): 879-882.
Chicago
He, D., Yu, W., Chen, Z., Li, L., Zhu, K., Fan, S."Pathogenesis of the intravertebral vacuum of Kümmell's disease (Review)". Experimental and Therapeutic Medicine 12, no. 2 (2016): 879-882. https://doi.org/10.3892/etm.2016.3369
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