Open Access

Magnetic resonance imaging in pediatric sickle cell anemia (Review)

  • Authors:
    • Xinxian Zhang
    • Chenglong Li
    • Qiancheng Li
  • View Affiliations

  • Published online on: June 2, 2016     https://doi.org/10.3892/etm.2016.3417
  • Pages: 555-558
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Sickle cell disease is the result of altered genetic make up due to hereditary encounter and its form as homozygous sickle cell anemia is the most common and severe. The disease is characterized by chronic anemia, recurrent pain crises and vascular occlusion. Neurologically, there is a high incidence of stroke in childhood, as well as cognitive dysfunction. Newborn screening programmes and preventative treatments have allowed a much longer lifespan. However, recently, neurological research has shifted to characterizing more subtle aspects of brain development and functioning that may be critically important to the individual's quality of life. The present review article examines the neurological and neurocognitive complications of sickle cell disease, and discusses the importance of magnetic resonance imaging scans in the management of the disease.
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August-2016
Volume 12 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Zhang X, Li C and Li Q: Magnetic resonance imaging in pediatric sickle cell anemia (Review). Exp Ther Med 12: 555-558, 2016
APA
Zhang, X., Li, C., & Li, Q. (2016). Magnetic resonance imaging in pediatric sickle cell anemia (Review). Experimental and Therapeutic Medicine, 12, 555-558. https://doi.org/10.3892/etm.2016.3417
MLA
Zhang, X., Li, C., Li, Q."Magnetic resonance imaging in pediatric sickle cell anemia (Review)". Experimental and Therapeutic Medicine 12.2 (2016): 555-558.
Chicago
Zhang, X., Li, C., Li, Q."Magnetic resonance imaging in pediatric sickle cell anemia (Review)". Experimental and Therapeutic Medicine 12, no. 2 (2016): 555-558. https://doi.org/10.3892/etm.2016.3417