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Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation

  • Authors:
    • Shi-Yan Yan
    • Yi Zhang
    • Chao Sun
    • Hai-Xia Cao
    • Guang-Ming Li
    • Yu-Qin Wang
    • Jian-Gao Fan
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China
    Copyright: © Yan et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1345-1348
    |
    Published online on: June 10, 2016
       https://doi.org/10.3892/etm.2016.3448
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Abstract

Primary liver cancer has a high incidence and high mortality rates, and currently the only viable option is surgery, although there are a number of difficulties related to this method. The aim of the present study was to investigate the potential advantages of the real-time contrast-enhanced ultrasonography (CEUS) for microwave ablation of primary liver cancer. One hundred patients with primary liver cancer were included in the study. The patients were divided into the ordinary ultrasonography and the CEUS groups. For the ordinary ultrasonography group, the ordinary ultrasonography-guided microwave ablation method was used, while microwave ablation under the guidance of CEUS was conducted for the CEUS group. The size of lesions and clearness of the tumor boundary prior to surgery in the two groups were compared. Additionally, postoperative complications and the survival rate were monitored. Lesion boundary areas measured by CEUS were significantly larger than those measured with ordinary ultrasonography. The incidence rate of postoperative pain, fever, intra-abdominal hemorrhage and infection and other complications in the ordinary ultrasonography group were significantly higher than that in the CEUS group. The tumor recurrence rate in the CEUS group was significantly lower than that in the ordinary ultrasonography group. Seventy-two percent of patients in the CEUS group showed no progress, compared to 48% of in the ordinary ultrasonography group. The progress‑free survival rate in the CEUS group after 6 months was significantly higher than that in the ordinary ultrasonography group. Disease-free survival time in the CEUS group was considerably longer than the control group. In conclusion, the guidance of real‑time CEUS on the primary liver cancer microwave ablation treatment can achieve good intra-operative results. It offers a real-time guidance effect, improves survival time and reduces the incidence of complications.
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1 

Kim AY, Lee MW, Rhim H, Cha DI, Choi D, Kim YS, Lim HK and Cho SW: Pretreatment evaluation with contrast-enhanced ultrasonography for percutaneous radiofrequency ablation of hepatocellular carcinomas with poor conspicuity on conventional ultrasonography. Korean J Radiol. 14:754–763. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Shah DR, Green S, Elliot A, McGahan JP and Khatri VP: Current oncologic applications of radiofrequency ablation therapies. World J Gastrointest Oncol. 5:71–80. 2013. View Article : Google Scholar : PubMed/NCBI

3 

Mauri G, Cova L, De Beni S, Ierace T, Tondolo T, Cerri A, Goldberg SN and Solbiati L: Real-time US-CT/MRI image fusion for guidance of thermal ablation of liver tumors undetectable with US: results in 295 cases. Cardiovasc Intervent Radiol. 38:143–151. 2015. View Article : Google Scholar : PubMed/NCBI

4 

Wolf FJ, Aswad B, Ng T and Dupuy DE: Intraoperative microwave ablation of pulmonary malignancies with tumor permittivity feedback control: ablation and resection study in 10 consecutive patients. Radiology. 262:353–360. 2012. View Article : Google Scholar : PubMed/NCBI

5 

Nazem F, Ahmadian A, Seraj ND and Giti M: Two-stage point-based registration method between ultrasound and CT imaging of the liver based on ICP and unscented Kalman filter: a phantom study. Int J CARS. 9:39–48. 2014. View Article : Google Scholar

6 

Bruix J and Sherman M: American Association for the Study of Liver Diseases: Management of hepatocellular carcinoma: an update. Hepatology. 53:1020–1022. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Sporea I, Badea R, Martie A, Dumitru E, Ioaniţescu S, Şirli R, Socaciu M, Popescu A, Dănilă M and Voiculescu M: Contrast Enhanced Ultrasound for the evaluation of focal liver lesions in daily practice. A multicentre study. Med Ultrason. 14:95–100. 2012.PubMed/NCBI

8 

Takahashi M, Maruyama H, Shimada T, Kamezaki H, Sekimoto T, Kanai F and Yokosuka O: Characterization of hepatic lesions (≤30 mm) with liver-specific contrast agents: a comparison between ultrasound and magnetic resonance imaging. Eur J Radiol. 82:75–84. 2013. View Article : Google Scholar : PubMed/NCBI

9 

Sparchez Z, Radu P, Zaharia T, Kacso G, Grigorescu I, Botis G and Badea R: Usefulness of contrast enhanced ultrasound guidance in percutaneous biopsies of liver tumors. J Gastrointestin Liver Dis. 20:191–196. 2011.PubMed/NCBI

10 

Zhang D, Liang P, Yu X, Cheng Z, Han Z, Yu J and Liu F: The value of artificial pleural effusion for percutaneous microwave ablation of liver tumour in the hepatic dome: a retrospective case-control study. Int J Hyperther. 29:663–670. 2013. View Article : Google Scholar

11 

Widmann G, Schullian P, Haidu M and Bale R: Stereotactic radiofrequency ablation (SRFA) of liver lesions: technique effectiveness, safety, and interoperator performance. Cardiovasc Intervent Radiol. 35:570–580. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Mariani A, Kwiecinski W, Pernot M, Balvay D, Tanter M, Clement O, Cuenod CA and Zinzindohoue F: Real time shear waves elastography monitoring of thermal ablation: in vivo evaluation in pig livers. J Surg Res. 188:37–43. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Liu F, Liang P, Yu X, Lu T, Cheng Z, Lei C and Han Z: A three-dimensional visualisation preoperative treatment planning system in microwave ablation for liver cancer: a preliminary clinical application. Int J Hyperther. 29:671–677. 2013. View Article : Google Scholar

14 

Wang XL, Li K, Su ZZ, Huang ZP, Wang P and Zheng RQ: Assessment of radiofrequency ablation margin by MRI-MRI image fusion in hepatocellular carcinoma. World J Gastroenterol. 21:5345–5351. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Correa-Gallego C, Karkar AM, Monette S, Ezell PC, Jarnagin WR and Kingham TP: Intraoperative ultrasound and tissue elastography measurements do not predict the size of hepatic microwave ablations. Acad Radiol. 21:72–78. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Mauri G, Porazzi E, Cova L, Restelli U, Tondolo T, Bonfanti M, Cerri A, Ierace T, Croce D and Solbiati L: Intraprocedural contrast-enhanced ultrasound (CEUS) in liver percutaneous radiofrequency ablation: clinical impact and health technology assessment. Insights Imaging. 5:209–216. 2014. View Article : Google Scholar : PubMed/NCBI

17 

Asvadi NH, Anvari A, Uppot RN, Thabet A, Zhu AX and Arellano RS: CT-guided percutaneous microwave ablation of tumors in the hepatic dome: assessment of efficacy and safety. J Vasc Interv Radiol. 27:496–502. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Zhang M, Liang P, Cheng ZG, Yu XL, Han ZY and Yu J: Efficacy and safety of artificial ascites in assisting percutaneous microwave ablation of hepatic tumours adjacent to the gastrointestinal tract. Int J Hyperther. 30:134–141. 2014. View Article : Google Scholar

19 

Li M, Yu XL, Liang P, Liu F, Dong B and Zhou P: Percutaneous microwave ablation for liver cancer adjacent to the diaphragm. Int J Hyperther. 28:218–226. 2012. View Article : Google Scholar

20 

Wu J, Yang W, Yin S, Wu J, Wu W, Yan K and Chen M: Role of contrast-enhanced ultrasonography in percutaneous radiofrequency ablation of liver metastases and efficacy evaluation. Chin J Cancer Res. 25:143–154. 2013.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Yan S, Zhang Y, Sun C, Cao H, Li G, Wang Y and Fan J: Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation. Exp Ther Med 12: 1345-1348, 2016.
APA
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., & Fan, J. (2016). Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation. Experimental and Therapeutic Medicine, 12, 1345-1348. https://doi.org/10.3892/etm.2016.3448
MLA
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., Fan, J."Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation". Experimental and Therapeutic Medicine 12.3 (2016): 1345-1348.
Chicago
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., Fan, J."Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1345-1348. https://doi.org/10.3892/etm.2016.3448
Copy and paste a formatted citation
x
Spandidos Publications style
Yan S, Zhang Y, Sun C, Cao H, Li G, Wang Y and Fan J: Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation. Exp Ther Med 12: 1345-1348, 2016.
APA
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., & Fan, J. (2016). Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation. Experimental and Therapeutic Medicine, 12, 1345-1348. https://doi.org/10.3892/etm.2016.3448
MLA
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., Fan, J."Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation". Experimental and Therapeutic Medicine 12.3 (2016): 1345-1348.
Chicago
Yan, S., Zhang, Y., Sun, C., Cao, H., Li, G., Wang, Y., Fan, J."Comparison of real-time contrast-enhanced ultrasonography and standard ultrasonography in liver cancer microwave ablation". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1345-1348. https://doi.org/10.3892/etm.2016.3448
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