Open Access

Association between alcohol and Alzheimer's disease (Review)

  • Authors:
    • Wen-Juan Huang
    • Xia Zhang
    • Wei-Wei Chen
  • View Affiliations

  • Published online on: June 14, 2016     https://doi.org/10.3892/etm.2016.3455
  • Pages: 1247-1250
  • Copyright: © Huang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Alzheimer's disease (AD) is a neurodegenerative disease characterized by dense deposition of amyloid-β (Aβ) protein in the brain, failure of the memory and dementia. At present, there is no cure for AD and current treatments only provide a temporary reduction of symptoms. Thus, there is a need for effective preventive/curative strategic approaches. Accordingly, epidemiological studies have reported a reduction in the prevalence of AD in individuals ingesting low amounts of alcohol, while a moderate consumption of ethanol may protect against Aβ. These data are conflicting with other observations that assigned detrimental effects of heavy alcohol use on brain function, which are apparently similar to those observed in AD. These discrepancies questioned whether or not alcohol is a protective agent against the development of AD, whether the probable protective effects are influenced by the quantity and/or frequency of drinking. These issues are addressed in this review with the aim to suggest the real risk of alcohol for developing or preventing AD.
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September-2016
Volume 12 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Huang W, Zhang X and Chen W: Association between alcohol and Alzheimer's disease (Review). Exp Ther Med 12: 1247-1250, 2016
APA
Huang, W., Zhang, X., & Chen, W. (2016). Association between alcohol and Alzheimer's disease (Review). Experimental and Therapeutic Medicine, 12, 1247-1250. https://doi.org/10.3892/etm.2016.3455
MLA
Huang, W., Zhang, X., Chen, W."Association between alcohol and Alzheimer's disease (Review)". Experimental and Therapeutic Medicine 12.3 (2016): 1247-1250.
Chicago
Huang, W., Zhang, X., Chen, W."Association between alcohol and Alzheimer's disease (Review)". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1247-1250. https://doi.org/10.3892/etm.2016.3455