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Review Open Access

Association between alcohol and Alzheimer's disease (Review)

  • Authors:
    • Wen-Juan Huang
    • Xia Zhang
    • Wei-Wei Chen
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, Xuzhou Central Hospital, Xuzhou, Jiangsu 221009, P.R. China
    Copyright: © Huang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1247-1250
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    Published online on: June 14, 2016
       https://doi.org/10.3892/etm.2016.3455
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Abstract

Alzheimer's disease (AD) is a neurodegenerative disease characterized by dense deposition of amyloid-β (Aβ) protein in the brain, failure of the memory and dementia. At present, there is no cure for AD and current treatments only provide a temporary reduction of symptoms. Thus, there is a need for effective preventive/curative strategic approaches. Accordingly, epidemiological studies have reported a reduction in the prevalence of AD in individuals ingesting low amounts of alcohol, while a moderate consumption of ethanol may protect against Aβ. These data are conflicting with other observations that assigned detrimental effects of heavy alcohol use on brain function, which are apparently similar to those observed in AD. These discrepancies questioned whether or not alcohol is a protective agent against the development of AD, whether the probable protective effects are influenced by the quantity and/or frequency of drinking. These issues are addressed in this review with the aim to suggest the real risk of alcohol for developing or preventing AD.
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Copy and paste a formatted citation
Spandidos Publications style
Huang W, Zhang X and Chen W: Association between alcohol and Alzheimer's disease (Review). Exp Ther Med 12: 1247-1250, 2016.
APA
Huang, W., Zhang, X., & Chen, W. (2016). Association between alcohol and Alzheimer's disease (Review). Experimental and Therapeutic Medicine, 12, 1247-1250. https://doi.org/10.3892/etm.2016.3455
MLA
Huang, W., Zhang, X., Chen, W."Association between alcohol and Alzheimer's disease (Review)". Experimental and Therapeutic Medicine 12.3 (2016): 1247-1250.
Chicago
Huang, W., Zhang, X., Chen, W."Association between alcohol and Alzheimer's disease (Review)". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1247-1250. https://doi.org/10.3892/etm.2016.3455
Copy and paste a formatted citation
x
Spandidos Publications style
Huang W, Zhang X and Chen W: Association between alcohol and Alzheimer's disease (Review). Exp Ther Med 12: 1247-1250, 2016.
APA
Huang, W., Zhang, X., & Chen, W. (2016). Association between alcohol and Alzheimer's disease (Review). Experimental and Therapeutic Medicine, 12, 1247-1250. https://doi.org/10.3892/etm.2016.3455
MLA
Huang, W., Zhang, X., Chen, W."Association between alcohol and Alzheimer's disease (Review)". Experimental and Therapeutic Medicine 12.3 (2016): 1247-1250.
Chicago
Huang, W., Zhang, X., Chen, W."Association between alcohol and Alzheimer's disease (Review)". Experimental and Therapeutic Medicine 12, no. 3 (2016): 1247-1250. https://doi.org/10.3892/etm.2016.3455
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