Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients

Shigeishi,Hideo; Ohta,Kouji; Fujimoto,Shinichi; Nakagawa,Takayuki; Mizuta,Kuniko; Ono,Shigehiro; Shimasue,Hiroshi; Ninomiya,Yoshiaki; Higashikawa,Koichiro; Tada,Misato; Ishida,Fumi; Okui,Gaku; Okumura,Toshiya; Fukui,Akiko; Kubozono,Kazumi; Yamamoto,Kazuhiro; Ishida,Yoko; Seino,Sayaka; Hashikata,Miho; Sasaki,Kazuki; Naruse,Takako; Rahman,Mohammad  Zeshaan; Uetsuki,Ryo; Nimiya,Akiko; Takamoto,Megumi; Dainobu,Kana; Tokikazu,Tomoko; Nishi,Hiromi; Sugiyama,Masaru; Takechi,Masaaki

doi:10.3892/etm.2016.3532

September-2016 Volume 12 Issue 3

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September-2016 Volume 12 Issue 3

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Article

Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients

Authors:
- Hideo Shigeishi
- Kouji Ohta
- Shinichi Fujimoto
- Takayuki Nakagawa
- Kuniko Mizuta
- Shigehiro Ono
- Hiroshi Shimasue
- Yoshiaki Ninomiya
- Koichiro Higashikawa
- Misato Tada
- Fumi Ishida
- Gaku Okui
- Toshiya Okumura
- Akiko Fukui
- Kazumi Kubozono
- Kazuhiro Yamamoto
- Yoko Ishida
- Sayaka Seino
- Miho Hashikata
- Kazuki Sasaki
- Takako Naruse
- Mohammad Zeshaan Rahman
- Ryo Uetsuki
- Akiko Nimiya
- Megumi Takamoto
- Kana Dainobu
- Tomoko Tokikazu
- Hiromi Nishi
- Masaru Sugiyama
- Masaaki Takechi
View Affiliations / Copyright

Affiliations: Department of Oral and Maxillofacial Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734‑8553, Japan, Oral Hygiene Section, Hiroshima University Hospital, Hiroshima 734‑8553, Japan, Department of General Dentistry, Hiroshima University Hospital, Hiroshima 734‑8553, Japan, Department of Public Oral Health, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734‑8553, Japan
Pages: 1922-1928
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Published online on: July 19, 2016

https://doi.org/10.3892/etm.2016.3532
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Abstract

The records of 70 patients with oral cancer who were treated at a single institution between 2008 and 2014 were reviewed. The body temperature, white blood cell count, and C‑reactive protein (CRP) levels were compared between those who had received preoperative oral care (oral care group) and those who had not received any (non‑oral care group). When the patients were divided into those who underwent minimally invasive surgery and those who underwent severely invasive surgery, the mean CRP level in the early postoperative period was lower in the oral care group as compared with the non‑oral care group in those who underwent minimally invasive surgery as well as those who underwent severely invasive surgery. However, the mean CRP level was most evidently reduced in the severely invasive group on days 1 and 3‑5. However, no significant differences were observed with regard to the percentage of postoperative infectious complications (for example, surgical site infection, anastomotic leak and pneumonia) between the oral care (13.6%) and non‑oral care (20.8%) groups, though a reduced prevalence of postoperative complications following preoperative oral care was noted. The results of the present study suggest that preoperative oral care can decrease inflammation during the early postoperative stage in patients with oral cancer who undergo severely invasive surgery.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients

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