Complete prefrontal lobe isolation surgery for recurrent epilepsy: A case report

  • Authors:
    • Shaoya Yin
    • Weipeng Jin
    • Qingyun Li
    • Mei Feng
    • Keke Feng
    • Hui Shao
    • Xueqing Zhang
    • Shimin Wang
  • View Affiliations

  • Published online on: September 16, 2016     https://doi.org/10.3892/etm.2016.3714
  • Pages: 3029-3034
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Abstract

Epileptogenic focus resection is less effective for the treatment of frontal lobe epilepsy compared with temporal lobe epilepsy. However, there is currently a lack of effective therapeutic options for patients with frontal lobe epilepsy who are unsuitable for epileptogenic focus resection (such patients with epileptogenic foci in one frontal lobe in which the precise epileptic foci cannot be determined), or who experience recurrent epilepsy following epileptogenic focus resection. The present study reports a patient with frontal lobe epilepsy who underwent successful frontal lobe isolation surgery following a previous unsuccessful epileptogenic focus resection surgery. To ensure complete isolation of the prefrontal lobe, the surgery included division of the anterior commissure and the anterior part of the corpus callosum. The patient was followed‑up for 16 months. Although the follow‑up electroencephalogram presented a number of sharp waves on the affected side, the patient did not experience any seizures. The results suggest that prefrontal lobe isolation is an effective method of treating frontal lobe epilepsy, as division of the anterior commissure and the anterior part of the corpus callosum ensures disconnection of the prefrontal lobe from other regions of the brain.
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November-2016
Volume 12 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Yin S, Jin W, Li Q, Feng M, Feng K, Shao H, Zhang X and Wang S: Complete prefrontal lobe isolation surgery for recurrent epilepsy: A case report. Exp Ther Med 12: 3029-3034, 2016
APA
Yin, S., Jin, W., Li, Q., Feng, M., Feng, K., Shao, H. ... Wang, S. (2016). Complete prefrontal lobe isolation surgery for recurrent epilepsy: A case report. Experimental and Therapeutic Medicine, 12, 3029-3034. https://doi.org/10.3892/etm.2016.3714
MLA
Yin, S., Jin, W., Li, Q., Feng, M., Feng, K., Shao, H., Zhang, X., Wang, S."Complete prefrontal lobe isolation surgery for recurrent epilepsy: A case report". Experimental and Therapeutic Medicine 12.5 (2016): 3029-3034.
Chicago
Yin, S., Jin, W., Li, Q., Feng, M., Feng, K., Shao, H., Zhang, X., Wang, S."Complete prefrontal lobe isolation surgery for recurrent epilepsy: A case report". Experimental and Therapeutic Medicine 12, no. 5 (2016): 3029-3034. https://doi.org/10.3892/etm.2016.3714