Psychiatric symptoms and limb tremors associated with central pontine myelinolysis: A case of alcoholism without hyponatremia

Feng,Xue‑Min; Zhao,Teng; Zhou,Chun‑Kui; Liu,Jing‑Yao

doi:10.3892/etm.2016.3780

November-2016 Volume 12 Issue 5

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November-2016 Volume 12 Issue 5

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Article

Psychiatric symptoms and limb tremors associated with central pontine myelinolysis: A case of alcoholism without hyponatremia

Authors:
- Xue‑Min Feng
- Teng Zhao
- Chun‑Kui Zhou
- Jing‑Yao Liu
View Affiliations / Copyright

Affiliations: Department of Neurology, The First Hospital, Jilin University, Changchun, Jilin 130031, P.R. China
Pages: 3485-3487
|
Published online on: October 4, 2016

https://doi.org/10.3892/etm.2016.3780
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Abstract

Central pontine myelinolysis (CPM), also known as osmotic demyelination syndrome, is a rare demyelinating disorder characterized by the loss of myelin in the center of the basis pontis. In this case report, an alcoholic patient with CPM and acquired demyelinating lesion of the basis pontis is described. The patient is a 70 year‑old woman who presented with intermittent psychiatric symptoms and limb tremors following two months of alcohol abuse. During admission, magnetic resonance imaging (MRI) revealed hyperintensity on T2 weighted images and fluid‑attenuated inversion‑recovery imaging in the central pons without contrast enhancement. The patient's symptoms gradually improved following conservative treatment with vitamins B1 and B12. The one month follow‑up MRI showed a significant reduction of the pontine injury.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Psychiatric symptoms and limb tremors associated with central pontine myelinolysis: A case of alcoholism without hyponatremia

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