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Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy

  • Authors:
    • Yuyan Hou
    • Fucheng Zhang
    • Zhiqiang Liu
    • Shuhong Su
    • Xiao Wu
    • Zhifang Wang
  • View Affiliations / Copyright

    Affiliations: Department of Cardiovascular Medicine, Xinxiang Central Hospital, Xinxiang, Henan 453000, P.R. China
    Copyright: © Hou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 131-134
    |
    Published online on: November 29, 2016
       https://doi.org/10.3892/etm.2016.3933
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Abstract

The aim of the present study was to compare the value of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy, and provide discussion on clinical reasonably chosen medicine. A total of 60 cases of coronary artery disease complicated with diabetic nephropathy were randomly divided for telmisartan (80 mg/day) treatment (n=32), enalapril (10 mg/day) treatment (n=28), while the rest of the therapy was kept the same. After 12 weeks, the clinical effects were compared between different groups. It was found that in comparison with enalapril group, the left ventricular ejection fraction of telmisartan group was significantly higher, and left ventricular end‑diastolic diameter was significantly lower (P<0.05). The serum creatinine level and 24‑h protein of telmisartan group were significantly lower than that for the enalapril group (P<0.05). In conclusion, the regular telmisartan treatment for patients with coronary artery disease complicated with diabetic nephropathy is better than enalapril on ventricular remodeling and kidney prognosis.
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Copy and paste a formatted citation
Spandidos Publications style
Hou Y, Zhang F, Liu Z, Su S, Wu X and Wang Z: Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy. Exp Ther Med 13: 131-134, 2017.
APA
Hou, Y., Zhang, F., Liu, Z., Su, S., Wu, X., & Wang, Z. (2017). Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy. Experimental and Therapeutic Medicine, 13, 131-134. https://doi.org/10.3892/etm.2016.3933
MLA
Hou, Y., Zhang, F., Liu, Z., Su, S., Wu, X., Wang, Z."Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy". Experimental and Therapeutic Medicine 13.1 (2017): 131-134.
Chicago
Hou, Y., Zhang, F., Liu, Z., Su, S., Wu, X., Wang, Z."Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy". Experimental and Therapeutic Medicine 13, no. 1 (2017): 131-134. https://doi.org/10.3892/etm.2016.3933
Copy and paste a formatted citation
x
Spandidos Publications style
Hou Y, Zhang F, Liu Z, Su S, Wu X and Wang Z: Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy. Exp Ther Med 13: 131-134, 2017.
APA
Hou, Y., Zhang, F., Liu, Z., Su, S., Wu, X., & Wang, Z. (2017). Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy. Experimental and Therapeutic Medicine, 13, 131-134. https://doi.org/10.3892/etm.2016.3933
MLA
Hou, Y., Zhang, F., Liu, Z., Su, S., Wu, X., Wang, Z."Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy". Experimental and Therapeutic Medicine 13.1 (2017): 131-134.
Chicago
Hou, Y., Zhang, F., Liu, Z., Su, S., Wu, X., Wang, Z."Effect of telmisartan and enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease complicated with diabetic nephropathy". Experimental and Therapeutic Medicine 13, no. 1 (2017): 131-134. https://doi.org/10.3892/etm.2016.3933
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