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Article Open Access

Protective effects of baicalin on rabbit articular chondrocytes in vitro

Corrigendum in: /10.3892/etm.2021.9768
Retraction in: /10.3892/etm.2023.12236
  • Authors:
    • Xianyuan Huang
    • Huayu Wu
    • Liqin Wang
    • Li Zheng
    • Jinmin Zhao
  • View Affiliations / Copyright

    Affiliations: Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China, Department of Cell Biology and Genetics, School of Premedical Sciences, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China, Department of Radiology, The First Affiliated Hospital, Sun Yat‑Sen University, Guangzhou, Guangdong 510275, P.R. China
    Copyright: © Huang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1267-1274
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    Published online on: February 10, 2017
       https://doi.org/10.3892/etm.2017.4116
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Abstract

Drug therapy is one of the typical treatments for post‑injury inflammation of cartilage. Traditional Chinese herbs have potential as treatments, as their long history of clinical application has demonstrated they are effective and induce minimal side effects. Baicalin is a traditional Chinese medicine that has been used to treat inflammation, fever, ulcers and cancer for hundreds of years. Previous studies have demonstrated that baicalin may decrease levels of interleukin‑1β and suppress the expression of type‑I collagen, thus attenuating cartilage degeneration. In the present study, the effect of baicalin on chondrocytes was assessed by examining the morphology, proliferation, extracellular matrix (ECM) synthesis and cartilage‑specific gene expression of chondrocytes. The results indicated that baicalin may promote the proliferation of articular chondrocytes, secretion of cartilage ECM and collagen type II, aggrecan and SRY box (Sox) 9 gene upregulation. The expression of collagen I, a marker of chondrocyte dedifferentiation, was downregulated by baicalin; therefore, baicalin may maintain the phenotype of chondrocytes. Within the recommended concentrations of baicalin ranging from 0.625‑6.25 µmol/l cell proliferation was increased and a 1.25 µmol/l dose of baicalin exerted the most positive effect on articular chondrocytes. The results of the present study may therefore indicate that baicalin may be used as a novel agent promoting the repair of articular cartilage damage.
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View References

1 

Pasold J, Zander K, Heskamp B, Gruttner C, Luthen F, Tischer T, Jonitz-Heincke A and Bader R: Positive impact of IGF-1-coupled nanoparticles on the differentiation potential of human chondrocytes cultured on collagen scaffolds. Int J Nanomedicine. 10:1131–1143. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Ishii I, Mizuta H, Sei A, Hirose J, Kudo S and Hiraki Y: Healing of full-thickness defects of the articular cartilage in rabbits using fibroblast growth factor-2 and a fibrin sealant. J Bone Joint Surg Br. 89:693–700. 2007. View Article : Google Scholar : PubMed/NCBI

3 

Oda K and Minata M: Drug free remission after steroid-dependent disappearance of lymphoproliferative disorder in rheumatoid arthritis patient treated with TNF-alpha blockade: Case study. Springerplus. 4:412015. View Article : Google Scholar : PubMed/NCBI

4 

Buckwalter JA and Mankin HJ: Articular cartilage: Tissue design and chondrocyte-matrix interactions. Instr Course Lect. 47:477–486. 1998.PubMed/NCBI

5 

Rahman R Abdul, Sukri N Mohamad, Md Nazir N, Radzi MA Ahmad, Zulkifly AH, Che Ahmad A, Hashi AA, Rahman S Abdul and Sha'ban M: The potential of 3-dimensional construct engineered from poly(lactic-co-glycolic acid)/fibrin hybrid scaffold seeded with bone marrow mesenchymal stem cells for in vitro cartilage tissue engineering. Tissue Cell. 47:420–430. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Kojima K, Bonassar LJ, Roy AK, Mizuno H, Cortiella J and Vacanti CA: A composite tissue-engineered trachea using sheep nasal chondrocyte and epithelial cells. FASEB J. 17:823–828. 2003. View Article : Google Scholar : PubMed/NCBI

7 

Kojima K, Bonassar LJ, Roy AK, Vacanti CA and Cortiella J: Autologous tissue-engineered trachea with sheep nasal chondrocytes. J Thorac Cardiovasc Surg. 123:1177–1184. 2002. View Article : Google Scholar : PubMed/NCBI

8 

Ting SY, Montagne K, Nishimura Y, Ushida T and Furukawa KS: Modulation of the effect of transforming growth factor-β3 by low-intensity pulsed ultrasound on scaffold-free dedifferentiated articular bovine chondrocyte tissues. Tissue Eng Part C Methods. 21:1005–1014. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Liu Q, Li J, Hartstone-Rose A, Wang J, Li J, Janicki JS and Fan D: Chinese herbal compounds for the prevention and treatment of atherosclerosis: Experimental EVIDENCE AND MECHANISMS. Evid Based Complement Alternat Med. 2015:7526102015.PubMed/NCBI

10 

Lu J, Wang JS and Kong LY: Anti-inflammatory effects of Huang-Lian-Jie-Du decoction, its two fractions and four typical compounds. J Ethnopharmacol. 134:911–918. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Fu P, Yang L, Sun Y, Ye L, Cao Z and Tang K: Target network differences between western drugs and Chinese herbal ingredients in treating cardiovascular disease. BMC Bioinformatics. 15 Suppl 4:S32014. View Article : Google Scholar : PubMed/NCBI

12 

Dun RL, Yao M, Yang L, Cui XJ, Mao JM, Peng Y and Qi GC: Traditional Chinese herb combined with surgery versus surgery for varicocele infertility: A systematic review and meta-analysis. Evid Based Complement Alternat Med. 2015:6890562015. View Article : Google Scholar : PubMed/NCBI

13 

Tsai CC, Lin MT, Wang JJ, Liao JF and Huang WT: The antipyretic effects of baicalin in lipopolysaccharide-evoked fever in rabbits. Neuropharmacology. 51:709–717. 2006. View Article : Google Scholar : PubMed/NCBI

14 

He Z, Li B, Rankin GO, Rojanasakul Y and Chen YC: Selecting bioactive phenolic compounds as potential agents to inhibit proliferation and VEGF expression in human ovarian cancer cells. Oncol Lett. 9:1444–1450. 2015.PubMed/NCBI

15 

Xiao JR, Do CW and To CH: Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders. J Ocul Pharmacol Ther. 30:605–614. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Shen YC, Chiou WF, Chou YC and Chen CF: Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. Eur J Pharmacol. 465:171–181. 2003. View Article : Google Scholar : PubMed/NCBI

17 

Ding Y, Dou J, Teng Z, Yu J, Wang T, Lu N, Wang H and Zhou C: Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase. Arch Virol. 159:3269–3278. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Gao Z, Huang K and Xu H: Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells. Pharmacol Res. 43:173–178. 2001. View Article : Google Scholar : PubMed/NCBI

19 

Chang CP, Huang WT, Cheng BC, Hsu CC and Lin MT: The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. Neuropharmacology. 52:1024–1033. 2007. View Article : Google Scholar : PubMed/NCBI

20 

Hu Q, Noor M, Wong YF, Hylands PJ, Simmonds MS and Xu Q, Jiang D, Hendry BM and Xu Q: In vitro anti-fibrotic activities of herbal compounds and herbs. Nephrol Dial Transplant. 24:3033–3041. 2009. View Article : Google Scholar : PubMed/NCBI

21 

Zhang Y and Yao X: Role of c-Jun N-terminal kinase and p38/activation protein-1 in interleukin-1β-mediated type I collagen synthesis in rat hepatic stellate cells. APMIS. 120:101–107. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Liu L, Liu Q, Lin X, Wei QJ and Zheng L: Effect of JEZTC, a synthetic compound, on proliferation and phenotype maintenance of rabbit articular chondrocytes in vitro. In Vitro Cell Dev Biol Anim. 50:982–991. 2014. View Article : Google Scholar : PubMed/NCBI

23 

Farndale RW, Buttle DJ and Barrett AJ: Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta. 883:173–177. 1986. View Article : Google Scholar : PubMed/NCBI

24 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C (T)) Method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

25 

Smith GD, Knutsen G and Richardson JB: A clinical review of cartilage repair techniques. J Bone Joint Surg Br. 87:445–449. 2005. View Article : Google Scholar : PubMed/NCBI

26 

Vega A, Martin-Ferrero MA, Del Canto F, Alberca M, García V, Munar A, Orozco L, Soler R, Fuertes JJ, Huguet M, et al: Treatment of knee osteoarthritis with allogeneic bone marrow mesenchymal stem cells: A randomized controlled trial. Transplantation. 99:1681–1690. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Lee JH, Ahn J, Kim JW, Lee SG and Kim HP: Flavonoids from the aerial parts of Houttuynia cordata attenuate lung inflammation in mice. Arch Pharm Res. 38:1304–1311. 2015. View Article : Google Scholar : PubMed/NCBI

28 

Liu JJ, Huang TS, Cheng WF and Lu FJ: Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation. Int J Cancer. 106:559–565. 2003. View Article : Google Scholar : PubMed/NCBI

29 

Zhang D, Huang B, Xiong C and Yue Z: Pinocembrin inhibits matrix metalloproteinase expression in chondrocytes. IUBMB Life. 67:36–41. 2015. View Article : Google Scholar : PubMed/NCBI

30 

Mizuguchi S, Uyama T, Kitagawa H, Nomura KH, Dejima K, Gengyo-Ando K, Mitani S, Sugahara K and Nomura K: Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans. Nature. 423:443–448. 2003. View Article : Google Scholar : PubMed/NCBI

31 

Ancsin JB: Amyloidogenesis: Historical and modern observations point to heparan sulfate proteoglycans as a major culprit. Amyloid. 10:67–79. 2003. View Article : Google Scholar : PubMed/NCBI

32 

Shi S, Wang C, Acton AJ, Eckert GJ and Trippel SB: Role of Sox9 in growth factor regulation of articular chondrocytes. J Cell Biochem. 116:1391–1400. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Davies SR, Chang LW, Patra D, Xing X, Posey K, Hecht J, Stormo GD and Sandell LJ: Computational identification and functional validation of regulatory motifs in cartilage-expressed genes. Genome Res. 17:1438–1447. 2007. View Article : Google Scholar : PubMed/NCBI

34 

Li Y, Tew SR, Russell AM, Gonzalez KR, Hardingham TE and Hawkins RE: Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9. Tissue Eng. 10:575–584. 2004. View Article : Google Scholar : PubMed/NCBI

35 

Zamani S, Hashemibeni B, Esfandiari E, Kabiri A, Rabbani H and Abutorabi R: Assessment of TGF-b3 on production of aggrecan by human articular chondrocytes in pellet culture system. Adv Biomed Res. 3:542014. View Article : Google Scholar : PubMed/NCBI

36 

Svala E, Löfgren M, Sihlbom C, Rüetschi U, Lindahl A, Ekman S and Skiöldebrand E: An inflammatory equine model demonstrates dynamic changes of immune response and cartilage matrix molecule degradation in vitro. Connect Tissue Res. 56:315–325. 2015. View Article : Google Scholar : PubMed/NCBI

37 

Xing R, Kong Q, Xiang Z, Yang J, Luo J, Deng L and Xie H: Preliminary study on microRNA regulated osteogenic and chondrogenic differentiation of mouse stem cells. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 28:1009–1016. 2014.(In Chinese). PubMed/NCBI

38 

Yang X, Trehan SK, Guan Y, Sun C, Moore DC, Jayasuriya CT and Chen Q: Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem. 289:34768–34779. 2014. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Huang X, Wu H, Wang L, Zheng L and Zhao J: Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236. Exp Ther Med 13: 1267-1274, 2017.
APA
Huang, X., Wu, H., Wang, L., Zheng, L., & Zhao, J. (2017). Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236. Experimental and Therapeutic Medicine, 13, 1267-1274. https://doi.org/10.3892/etm.2017.4116
MLA
Huang, X., Wu, H., Wang, L., Zheng, L., Zhao, J."Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236". Experimental and Therapeutic Medicine 13.4 (2017): 1267-1274.
Chicago
Huang, X., Wu, H., Wang, L., Zheng, L., Zhao, J."Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236". Experimental and Therapeutic Medicine 13, no. 4 (2017): 1267-1274. https://doi.org/10.3892/etm.2017.4116
Copy and paste a formatted citation
x
Spandidos Publications style
Huang X, Wu H, Wang L, Zheng L and Zhao J: Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236. Exp Ther Med 13: 1267-1274, 2017.
APA
Huang, X., Wu, H., Wang, L., Zheng, L., & Zhao, J. (2017). Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236. Experimental and Therapeutic Medicine, 13, 1267-1274. https://doi.org/10.3892/etm.2017.4116
MLA
Huang, X., Wu, H., Wang, L., Zheng, L., Zhao, J."Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236". Experimental and Therapeutic Medicine 13.4 (2017): 1267-1274.
Chicago
Huang, X., Wu, H., Wang, L., Zheng, L., Zhao, J."Protective effects of baicalin on rabbit articular chondrocytes in vitro Corrigendum in /10.3892/etm.2021.9768 Retraction in /10.3892/etm.2023.12236". Experimental and Therapeutic Medicine 13, no. 4 (2017): 1267-1274. https://doi.org/10.3892/etm.2017.4116
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