Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema

Shao,Yi; Yu,Yao; Li,Cheng; Pei,Chong-Gang; Tu,Ping; Han,Yun; Gao,Gui-Ping

doi:10.3892/etm.2017.4145

April-2017 Volume 13 Issue 4

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April-2017 Volume 13 Issue 4

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Article Open Access

Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema

Authors:
- Yi Shao
- Yao Yu
- Cheng Li
- Chong-Gang Pei
- Ping Tu
- Yun Han
- Gui-Ping Gao
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Affiliations: Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang, Jiangxi 330006, P.R. China, Department of Endocrinology and Metabolism, The Third Hospital of Nanchang, Nanchang Key Laboratory of Diabetes, Nanchang, Jiangxi 330009, P.R. China, Fujian Province Key Laboratory of Ophthalmology and Vision Research, Eye Institute of Xiamen University, Xiamen, Fujian 361102, P.R. China

Copyright: © Shao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 1480-1484
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Published online on: February 21, 2017

https://doi.org/10.3892/etm.2017.4145
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Abstract

We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for macular edema in the First Affiliated Hospital of Nanchang University were enrolled in this study. Patients were randomly divided into two groups: i) The experimental group (n=39) and the control group (n=39). Patients in the experimental group were treated with Bevacizumab (Avastin®) combined with argon green laser, and those in the control group were treated exclusively with argon green laser. Therapeutic effects were compared, and postoperative adverse reactions caused by both treatment methods were compared. Our results showed that, after treatment, the macular foveal thickness was reduced noticeably in both groups, while the therapeutic effect of combined treatment was more prominent. Patients in the experimental group gained the best-corrected visual acuity after one month of treatment, while patients in the control group achieved that after three months of treatment. We concluded that the use of Avastin® combined with argon green laser was safe and effective. Visual acuity was improved obviously with minimum adverse reactions.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema

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