Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases (Review)

  • Authors:
    • Donatella Perrone
    • Maria Pia Fuggetta
    • Fatima Ardito
    • Andrea Cottarelli
    • Anna De Filippis
    • Giampietro Ravagnan
    • Salvatore De Maria
    • Lorenzo Lo Muzio
  • View Affiliations

  • Published online on: May 18, 2017     https://doi.org/10.3892/etm.2017.4472
  • Pages: 3-9
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Abstract

Health promotion strategies and lifestyle changes are important in disease prevention. Oral health has received a large amount of attention previously as it is a fundamental component of general health and it contributes to the quality of life. Therefore, the study of associations between diet, health and the presence of bioactive compounds in food is receiving a substantial amount of attention. In the present review the effects and targets of a natural polyohenolic stilbenoid compound; resveratrol (3,5,4'‑trihydroxystilbene; RSV) is assessed, and the future prospects for RSV in promoting oral health are considered. RSV is a phytoalexin, synthesized by a wide range of plants and abundantly extracted in grape skin, it has been purported to exert a multiplicity of anti‑inflammatory, anti‑viral, anti‑microbial, estrogenic, anticancer, cardioprotective, neuroprotective and immunomodulatory functions. In this review, following an introduction documenting the biochemistry of RSV and RSV glucosides, the bioavailability and pharmacokinetics of RSV are described. Considering its multiple properties, the present review has focused on the potential benefits of RSV as an antioxidant and chemopreventive agent.
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July-2017
Volume 14 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Perrone D, Fuggetta MP, Ardito F, Cottarelli A, De Filippis A, Ravagnan G, De Maria S and Lo Muzio L: Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases (Review). Exp Ther Med 14: 3-9, 2017
APA
Perrone, D., Fuggetta, M.P., Ardito, F., Cottarelli, A., De Filippis, A., Ravagnan, G. ... Lo Muzio, L. (2017). Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases (Review). Experimental and Therapeutic Medicine, 14, 3-9. https://doi.org/10.3892/etm.2017.4472
MLA
Perrone, D., Fuggetta, M. P., Ardito, F., Cottarelli, A., De Filippis, A., Ravagnan, G., De Maria, S., Lo Muzio, L."Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases (Review)". Experimental and Therapeutic Medicine 14.1 (2017): 3-9.
Chicago
Perrone, D., Fuggetta, M. P., Ardito, F., Cottarelli, A., De Filippis, A., Ravagnan, G., De Maria, S., Lo Muzio, L."Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases (Review)". Experimental and Therapeutic Medicine 14, no. 1 (2017): 3-9. https://doi.org/10.3892/etm.2017.4472