Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
July-2017 Volume 14 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July-2017 Volume 14 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques

  • Authors:
    • Hongxue Zhang
    • Jianwen Du
    • Hong Wang
    • Haili Wang
    • Jianhui Jiang
    • Jingjie Zhao
    • Huan Lu
  • View Affiliations / Copyright

    Affiliations: Department of UItrasonic Diagnosis, The Second Clinic, Institute of the Chengde Medical College, Chengde, Hebei 067000, P.R. China, Department of Pathology, The Second Clinic, Institute of the Chengde Medical College, Chengde, Hebei 067000, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 680-688
    |
    Published online on: May 31, 2017
       https://doi.org/10.3892/etm.2017.4525
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to compare the diagnostic values of ultrasound micro-flow imaging (SMI) and contrast-enhanced ultrasound (CEUS) for neovascularization in carotid plaques, and to investigate their capacities for predicting the risks of cerebral stroke. A total of 39 patients (64 carotid plaques) with severe carotid artery stenosis undergoing carotid endarterectomy were selected between February 2015 and February 2016, and SMI and CEUS were used to detect neovascularization in plaques. According to the CEUS dynamic graph of plaques, the enhanced intensity visual scales and contrast parameters were obtained. Carotid atherosclerotic plaques were divided into 4 groups. The differences in the enhanced intensity visual scales, contrast parameters, and gray-scale median (GSM) values among the 4 groups were analyzed. Carotid plaque tissue samples from patients were stained for CD34, and the consistency of the methods for the diagnosis of neovascularization in plaques was analyzed. The differences in GSM values, enhanced intensities, and enhanced densities among the 4 groups of plaques were statistically significant (F=29.365, χ2=29.025, χ2=30.871, P<0.001); the differences in enhanced intensities of carotid atherosclerotic plaques with different echo types were statistically significant (χ2=17.951, P<0.001). The enhanced intensity of plaques was negatively correlated with the GSM value (r=-0.376, P<0.01), and the enhanced density of plaques was negatively correlated with the GSM value (r=-0.252, P<0.01). SMI and CEUS grading had good consistency (κ=0.860>0), there were statistically significant differences in new vessel densities with different SMI gradings (P<0.001), and the clinical symptoms and severity were positively correlated with SMI grading (rs=0.592>0). In conclusion, SMI and CEUS have good consistency for evaluating neovascularization in carotid plaques, and have good clinical value for evaluating neovascularization in carotid plaques.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Gray-Weale AC, Graham JC, Burnett JR, Byrne K and Lusby RJ: Carotid artery atheroma: comparison of preoperative B-mode ultrasound appearance with carotid endarterectomy specimen pathology. J Cardiovasc Surg (Torino). 29:676–681. 1988.PubMed/NCBI

2 

Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, et al: From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: part I. Circulation. 108:1664–1672. 2003. View Article : Google Scholar : PubMed/NCBI

3 

Hellings WE, Peeters W, Moll FL, Piers SR, van Setten J, van der Spek PJ, De Vries JP, Seldenrijk KA, De Bruin PC, Vink A, et al: Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study. Circulation. 121:1941–1950. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Hingwala D, Kesavadas C, Sylaja PN, Thomas B and Kapilamoorthy TR: Multimodality imaging of carotid atherosclerotic plaque: going beyond stenosis. Indian J Radiol Imaging. 23:26–34. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Fleiner M, Kummer M, Mirlacher M, Sauter G, Cathomas G, Krapf R and Biedermann BC: Arterial neovascularization and inflammation in vulnerable patients: early and late signs of symptomatic atherosclerosis. Circulation. 110:2843–2850. 2004. View Article : Google Scholar : PubMed/NCBI

6 

Shah F, Balan P, Weinberg M, Reddy V, Neems R, Feinstein M, Dainauskas J, Meyer P, Goldin M and Feinstein SB: Contrast-enhanced ultrasound imaging of atherosclerotic carotid plaque neovascularization: a new surrogate marker of atherosclerosis? Vasc Med. 12:291–297. 2007. View Article : Google Scholar : PubMed/NCBI

7 

Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP and Narula J: Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol. 25:2054–2061. 2005. View Article : Google Scholar : PubMed/NCBI

8 

Staub D, Partovi S, Schinkel AF, Coll B, Uthoff H, Aschwanden M, Jaeger KA and Feinstein SB: Correlation of carotid artery atherosclerotic lesion echogenicity and severity at standard US with intraplaque neovascularization detected at contrast-enhanced US. Radiology. 258:618–626. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Russell DA, Wijeyaratne SM and Gough MJ: Changes in carotid plaque echomorphology with time since a neurologic event. J Vasc Surg. 45:367–372. 2007. View Article : Google Scholar : PubMed/NCBI

10 

Sztajzel R, Momjian S, Momjian-Mayor I, Murith N, Djebaili K, Boissard G, Comelli M and Pizolatto G: Stratified gray-scale median analysis and color mapping of the carotid plaque: correlation with endarterectomy specimen histology of 28 patients. Stroke. 36:741–745. 2005. View Article : Google Scholar : PubMed/NCBI

11 

Nakamura J, Nakamura T, Deyama J, Fujioka D, Kawabata K, Obata JE, Watanabe K, Watanabe Y and Kugiyama K: Assessment of carotid plaque neovascularization using quantitative analysis of contrast-enhanced ultrasound imaging is useful for risk stratification in patients with coronary artery disease. Int J Cardiol. 195:113–119. 2015. View Article : Google Scholar : PubMed/NCBI

12 

Fisher M, Paganini-Hill A, Martin A, Cosgrove M, Toole JF, Barnett HJ and Norris J: Carotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke. 36:253–257. 2005. View Article : Google Scholar : PubMed/NCBI

13 

ten Kate GL, van Dijk AC, van den Oord SC, Hussain B, Verhagen HJ, Sijbrands EJ, van der Steen AF, van der Lugt A and Schinkel AF: Usefulness of contrast-enhanced ultrasound for detection of carotid plaque ulceration in patients with symptomatic carotid atherosclerosis. Am J Cardiol. 112:292–298. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Vicenzini E, Giannoni MF, Sirimarco G, Ricciardi MC, Toscano M, Lenzi GL and Di Piero V: Imaging of plaque perfusion using contrast-enhanced ultrasound - clinical significance. Perspect Med. 1:44–50. 2012. View Article : Google Scholar

15 

Hoogi A, Adam D, Hoffman A, Kerner H, Reisner S and Gaitini D: Carotid plaque vulnerability: quantification of neovascularization on contrast-enhanced ultrasound with histopathologic correlation. AJR Am J Roentgenol. 196:431–436. 2011. View Article : Google Scholar : PubMed/NCBI

16 

Nandalur KR, Baskurt E, Hagspiel KD, Phillips CD and Kramer CM: Calcified carotid atherosclerotic plaque is associated less with ischemic symptoms than is noncalcified plaque on MDCT. AJR Am J Roentgenol. 184:295–298. 2005. View Article : Google Scholar : PubMed/NCBI

17 

Seo Y, Watanabe S, Ishizu T, Moriyama N, Takeyasu N, Maeda H, Ishimitsu T, Aonuma K and Yamaguchi I: Echolucent carotid plaques as a feature in patients with acute coronary syndrome. Circ J. 70:1629–1634. 2006. View Article : Google Scholar : PubMed/NCBI

18 

Grønholdt ML, Nordestgaard BG, Schroeder TV, Vorstrup S and Sillesen H: Ultrasonic echolucent carotid plaques predict future strokes. Circulation. 104:68–73. 2001. View Article : Google Scholar : PubMed/NCBI

19 

de Blois J, Stranden E, Jogestrand T, Henareh L and Agewall S: Echogenicity of the carotid intima-media complex and cardiovascular risk factors. Clin Physiol Funct Imaging. 32:400–403. 2012. View Article : Google Scholar : PubMed/NCBI

20 

Shalhoub J, Owen DR, Gauthier T, Monaco C, Leen EL and Davies AH: The use of contrast enhanced ultrasound in carotid arterial disease. Eur J Vasc Endovasc Surg. 39:381–387. 2010. View Article : Google Scholar : PubMed/NCBI

21 

Ogata T, Yasaka M, Wakugawa Y, Kitazono T and Okada Y: Morphological classification of mobile plaques and their association with early recurrence of stroke. Cerebrovasc Dis. 30:606–611. 2010. View Article : Google Scholar : PubMed/NCBI

22 

Higashida T, Kanno H, Nakano M, Funakoshi K and Yamamoto I: Expression of hypoxia-inducible angiogenic proteins (hypoxia- inducible factor-1alpha, vascular endothelial growth factor, and E26 transformation-specific-1) and plaque hemorrhage in human carotid atherosclerosis. J Neurosurg. 109:83–91. 2008. View Article : Google Scholar : PubMed/NCBI

23 

Lee SH, Lee JH, Yoo SY, Hur J, Kim HS and Kwon SM: Hypoxia inhibits cellular senescence to restore the therapeutic potential of old human endothelial progenitor cells via the hypoxia-inducible factor-1α-TWIST-p21 axis. Arterioscler Thromb Vasc Biol. 33:2407–2414. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Kim HS, Woo JS, Kim BY, Jang HH, Hwang SJ, Kwon SJ, Choi EY, Kim JB, Cheng X, Jin E, et al: Biochemical and clinical correlation of intraplaque neovascularization using contrast-enhanced ultrasound of the carotid artery. Atherosclerosis. 233:579–583. 2014. View Article : Google Scholar : PubMed/NCBI

25 

Sluimer JC, Gasc JM, van Wanroij JL, Kisters N, Groeneweg M, Gelpke MD Sollewijn, Cleutjens JP, van den Akker LH, Corvol P, Wouters BG, et al: Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. J Am Coll Cardiol. 51:1258–1265. 2008. View Article : Google Scholar : PubMed/NCBI

26 

Zhao X, Kong J, Zhao Y, Wang X, Bu P, Zhang C and Zhang Y: Gene silencing of TACE enhances plaque stability and improves vascular remodeling in a rabbit model of atherosclerosis. Sci Rep. 5:179392015. View Article : Google Scholar : PubMed/NCBI

27 

Wang YH, Zheng QC, Yuan GX and Ren JH: The application of ultrasound B-flow imaging in detection of carotid atherosclerotic micro-vessel with ischemic cerebrovascular disease. Saudi Med J. 33:1080–1086. 2012.PubMed/NCBI

28 

Lind L, Andersson J, Rönn M, Gustavsson T, Holdfelt P, Hulthe J, Elmgren A, Zilmer K and Zilmer M: Brachial artery intima-media thickness and echogenicity in relation to lipids and markers of oxidative stress in elderly subjects: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) Study. Lipids. 43:133–141. 2008. View Article : Google Scholar : PubMed/NCBI

29 

Schulte-Altedorneburg G, Droste DW, Haas N, Kemény V, Nabavi DG, Füzesi L and Ringelstein EB: Preoperative B-mode ultrasound plaque appearance compared with carotid endarterectomy specimen histology. Acta Neurol Scand. 101:188–194. 2000. View Article : Google Scholar : PubMed/NCBI

30 

Ostling G, Hedblad B, Berglund G and Gonçalves I: Increased echolucency of carotid plaques in patients with type 2 diabetes. Stroke. 38:2074–2078. 2007. View Article : Google Scholar : PubMed/NCBI

31 

Sabetai MM, Tegos TJ, Nicolaides AN, Dhanjil S, Pare GJ and Stevens JM: Reproducibility of computer-quantified carotid plaque echogenicity: can we overcome the subjectivity? Stroke. 31:2189–2196. 2000. View Article : Google Scholar : PubMed/NCBI

32 

Kyriacou EC, Petroudi S, Pattichis CS, Pattichis MS, Griffin M, Kakkos S and Nicolaides A: Prediction of high-risk asymptomatic carotid plaques based on ultrasonic image features. IEEE Trans Inf Technol Biomed. 16:966–973. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Östling G, Persson M, Hedblad B and Gonçalves I: Comparison of grey scale median (GSM) measurement in ultrasound images of human carotid plaques using two different softwares. Clin Physiol Funct Imaging. 33:431–435. 2013.PubMed/NCBI

34 

Mathiesen EB, Bønaa KH and Joakimsen O: Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the tromsø study. Circulation. 103:2171–2175. 2001. View Article : Google Scholar : PubMed/NCBI

35 

Ariyoshi K, Okuya S, Kunitsugu I, Matsunaga K, Nagao Y, Nomiyama R, Takeda K and Tanizawa Y: Ultrasound analysis of gray-scale median value of carotid plaques is a useful reference index for cerebro-cardiovascular events in patients with type 2 diabetes. J Diabetes Investig. 6:91–97. 2015. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang H, Du J, Wang H, Wang H, Jiang J, Zhao J and Lu H: Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques. Exp Ther Med 14: 680-688, 2017.
APA
Zhang, H., Du, J., Wang, H., Wang, H., Jiang, J., Zhao, J., & Lu, H. (2017). Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques. Experimental and Therapeutic Medicine, 14, 680-688. https://doi.org/10.3892/etm.2017.4525
MLA
Zhang, H., Du, J., Wang, H., Wang, H., Jiang, J., Zhao, J., Lu, H."Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques". Experimental and Therapeutic Medicine 14.1 (2017): 680-688.
Chicago
Zhang, H., Du, J., Wang, H., Wang, H., Jiang, J., Zhao, J., Lu, H."Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques". Experimental and Therapeutic Medicine 14, no. 1 (2017): 680-688. https://doi.org/10.3892/etm.2017.4525
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang H, Du J, Wang H, Wang H, Jiang J, Zhao J and Lu H: Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques. Exp Ther Med 14: 680-688, 2017.
APA
Zhang, H., Du, J., Wang, H., Wang, H., Jiang, J., Zhao, J., & Lu, H. (2017). Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques. Experimental and Therapeutic Medicine, 14, 680-688. https://doi.org/10.3892/etm.2017.4525
MLA
Zhang, H., Du, J., Wang, H., Wang, H., Jiang, J., Zhao, J., Lu, H."Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques". Experimental and Therapeutic Medicine 14.1 (2017): 680-688.
Chicago
Zhang, H., Du, J., Wang, H., Wang, H., Jiang, J., Zhao, J., Lu, H."Comparison of diagnostic values of ultrasound micro-flow imaging and contrast-enhanced ultrasound for neovascularization in carotid plaques". Experimental and Therapeutic Medicine 14, no. 1 (2017): 680-688. https://doi.org/10.3892/etm.2017.4525
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team