|
1
|
Parkin DM, Bray F, Ferlay J and Pisani P:
Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kuhar M, Sen S and Singh N: Role of
mitochondria in quercetin-enhanced chemotherapeutic response in
human non-small cell lung carcinoma H-520 cells. Anticancer Res.
26:1297–1303. 2006.PubMed/NCBI
|
|
3
|
Graham MV, Purdy JA, Emami B, Harms W,
Bosch W, Lockett MA and Perez CA: Clinical dose-volume histogram
analysis for pneumonitis after 3D treatment for non-small cell lung
cancer (NSCLC). Int J Radiat Oncol Biol Phys. 45:323–329. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kwa SL, Lebesque JV, Theuws JC, Marks LB,
Munley MT, Bentel G, Oetzel D, Spahn U, Graham MV, Drzymala RE, et
al: Radiation pneumonitis as a function of mean lung dose: An
analysis of pooled data of 540 patients. Int J Radiat Oncol Biol
Phys. 42:1–9. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Nair MP, Mahajan S, Reynolds JL, Aalinkeel
R, Nair H, Schwartz SA and Kandaswami C: The flavonoid quercetin
inhibits proinflammatory cytokine (tumor necrosis factor alpha)
gene expression in normal peripheral blood mononuclear cells via
modulation of the NF-kappa beta system. Clin Vaccine Immunol.
13:319–328. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Watanabe H, Suga A, Tsuchihashi Y, Hori A,
Kawakami K, Masaki H, Akiyama M, Ohishi K, Takahashi A, Nagatake T,
et al: Clinical study of radiation pneumonitis over 10 years. Nihon
Kyobu Shikkan Gakkai Zasshi. 33:384–388. 1995.(In Japanese).
PubMed/NCBI
|
|
7
|
Lee JC, Kinniry PA, Arguiri E, Serota M,
Kanterakis S, Chatterjee S, Solomides CC, Javvadi P, Koumenis C,
Cengel KA and Christofidou-Solomidou M: Dietary curcumin increases
antioxidant defenses in lung, ameliorates radiation-induced
pulmonary fibrosis, and improves survival in mice. Radiat Res.
173:590–601. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wu L, Huang Z, Qin P, Yao Y, Meng X, Zou
J, Zhu K and Ren G: Chemical characterization of a procyanidin-rich
extract from sorghum bran and its effect on oxidative stress and
tumor inhibition in vivo. J Agric Food Chem. 59:8609–8615. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Sharma SD, Meeran SM and Katiyar SK:
Proanthocyanidins inhibit in vitro and in vivo growth of human
non-small cell lung cancer cells by inhibiting the prostaglandin
E(2) and prostaglandin E(2) receptors. Mol Cancer Ther. 9:569–580.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Comalada M, Camuesco D, Sierra S,
Ballester I, Xaus J, Gálvez J and Zarzuelo A: In vivo quercitrin
anti-inflammatory effect involves release of quercetin, which
inhibits inflammation through down-regulation of the NF-kappaB
pathway. Eur J Immunol. 35:584–592. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Bournival J, Plouffe M, Renaud J,
Provencher C and Martinoli MG: Quercetin and sesamin protect
dopaminergic cells from MPP+-induced neuroinflammation
in a microglial (N9)-neuronal (PC12) coculture system. Oxid Med
Cell Longev. 2012:921–941. 2012. View Article : Google Scholar
|
|
12
|
Grande F, Parisi OI, Mordocco RA, Rocca C,
Puoci F, Scrivano L, Quintieri AM, Cantafio P, Ferla S, Brancale A,
et al: Quercetin derivatives as novel antihypertensive agents:
Synthesis and physiological characterization. Eur J Pharrm Sci.
82:161–170. 2016. View Article : Google Scholar
|
|
13
|
Boots AW, Haenen GR and Bast A: Health
effects of quercetin: From antioxidant to nutraceutical. Eur J
Pharmacol. 585:325–337. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Grande F, Parisi OI, Mordocco RA, Rocca C,
Puoci F, Scrivano L, Quintieri AM, Cantafio P, Ferla S, Brancale A,
et al: Quercetin derivatives as novel antihypertensive agents:
Synthesis and physiological characterization. Eur J Pharm Sci.
82:161–170. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Brito AF, Ribeiro M, Abrantes AM, Pires
AS, Teixo RJ, Tralhão JG and Botelho MF: Quercetin in cancer
treatment, alone or in combination with conventional therapeutics?
Curr Med Chem. 22:3025–3039. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kanter M: Protective effect of quercetin
on liver damage induced by chronic toluene exposure in rats.
Toxicol Ind Health. 28:483–491. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Fasolo D, Schwingel L, Holzschuh M,
Bassani V and Teixeira H: Validation of an isocratic LC method for
determination of quercetin and methylquercetin in topical
nanoemulsions. J Pharm Biomed Anal. 44:1174–1177. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Kumari A, Yadav SK, Pakade YB, Singh B and
Yadav SC: Development of biodegradable nanoparticles for delivery
of quercetin. Colloids Surf B Biointerfaces. 80:184–192. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Aytac Z, Kusku SI, Durgun E and Uyar T:
Quercetin/β-cyclodextrin inclusion complex embedded nanofibres:
Slow release and high solubility. Food Chem. 197:864–871. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chimento A, Sala M, Gomez-Monterrey IM,
Musella S, Bertamino A, Caruso A, Sinicropi MS, Sirianni R, Puoci
F, Parisi OI, et al: Biological activity of 3-chloro-azetidin-2-one
derivatives having interesting antiproliferative activity on human
breast cancer cell lines. Bioorg Med Chem Lett. 23:6401–6405. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhao J, Liu J, Wei T, Ma X, Cheng Q, Huo
S, Zhang C, Zhang Y, Duan X and Liang XJ: Quercetin-loaded
nanomicelles to circumvent human castration-resistant prostate
cancer in vitro and in vivo. Nanoscale. 8:5126–5138. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Crompton G: A brief history of inhaled
asthma therapy over the last fifty years. Prim Care Respir J.
15:326–331. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Otterson GA, Villalona-Calero MA, Sharma
S, Kris MG, Imondi A, Gerber M, White DA, Ratain MJ, Schiller JH,
Sandler A, et al: Phase I study of inhaled Doxorubicin for patients
with metastatic tumors to the lungs. Clin Cancer Res. 13:1246–1252.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Otterson GA, Villalona-Calero MA, Hicks W,
Pan X, Ellerton JA, Gettinger SN and Murren JR: Phase I/II study of
inhaled doxorubicin combined with platinum-based therapy for
advanced non-small cell lung cancer. Clin Cancer Res. 16:2466–2473.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Moon H, Choi HH, Lee JY, Moon HJ, Sim SS
and Kim CJ: Quercetin inhalation inhibits the asthmatic responses
by exposure to aerosolized-ovalbumin in conscious guinea-pigs. Arch
Pharm Res. 31:771–778. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Scalia S, Haghi M, Losi V, Trotta V, Young
PM and Traini D: Quercetin solid lipid microparticles: A flavonoid
for inhalation lung delivery. Eur J Pharm Sci. 49:278–285. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Scalia S, Trotta V, Traini D, Young PM,
Sticozzi C, Cervellati F and Valacchi G: Incorporation of quercetin
in respirable lipid microparticles: Effect on stability and
cellular uptake on A549 pulmonary alveolar epithelial cells.
Colloids Surf B Biointerfaces. 112:322–329. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Scalia S and Mezzena M: Incorporation of
quercetin in lipid microparticles: Effect on photo- and
chemical-stability. J Pharm Biomed Anal. 49:90–94. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Takashima K, Matsushima M, Hashimoto K,
Nose H, Sato M, Hashimoto N, Hasegawa Y and Kawabe T: Protective
effects of intratracheally administered quercetin on
lipopolysaccharide-induced acute lung injury. Respir Res.
15:1502014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Chang YC, Tsai MH, Sheu WH, Hsieh SC and
Chiang AN: The therapeutic potential and mechanisms of action of
quercetin in relation to lipopolysaccharide-induced sepsis in vitro
and in vivo. PLoS One. 8:e807442013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fischer AH, Jacobson KA, Rose J and Zeller
R: Hematoxylin and eosin staining of tissue and cell sections. CSH
Protoc. 2008:pdb.prot49862008.PubMed/NCBI
|
|
32
|
Henkenberens C, Janssen S, Lavae-Mokhtari
M, Leni K, Meyer A, Christiansen H, Bremer M and Dickgreber N:
Inhalative steroids as an individual treatment in symptomatic lung
cancer patients with radiation pneumonitis grade II after
radiotherapy - a single-centre experience. Radiat Oncol. 11:122016.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chiang CS, Liu WC, Jung SM, Chen FH, Wu
CR, McBride WH, Lee CC and Hong JH: Compartmental responses after
thoracic irradiation of mice: Strain differences. Int J Radiat
Oncol Biol Phys. 62:862–871. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Rübe CE, Wilfert F, Palm J, König J,
Burdak-Rothkamm S, Liu L, Schuck A, Willich N and Rübe C:
Irradiation induces a biphasic expression of pro-inflammatory
cytokines in the lung. Strahlenther Onkol. 180:442–448. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Tsoutsou PG: The interplay between
radiation and the immune system in the field of post-radical
pneumonitis and fibrosis and why it is important to understand it.
Expert Opin Pharmacother. 15:1781–1783. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Henkenberens C, Janssen S, Lavae-Mokhtari
M, Leni K, Meyer A, Christiansen H, Bremer M and Dickgreber N:
Inhalative steroids as an individual treatment in symptomatic lung
cancer patients with radiation pneumonitis grade II after
radiotherapy-a single-centre experience. Radiat Oncol. 11:122016.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Pietrofesa R, Turowski J, Tyagi S, Dukes
F, Arguiri E, Busch TM, Gallagher-Colombo SM, Solomides CC, Cengel
KA and Christofidou-Solomidou M: Radiation mitigating properties of
the lignan component in flaxseed. BMC Cancer. 13:1792013.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Adawi A, Zhang Y, Baggs R, Rubin P,
Williams J, Finkelstein J and Phipps RP: Blockade of CD40-CD40
ligand interactions protects against radiation-induced pulmonary
inflammation and fibrosis. Clin Immunol Immunopathol. 89:222–230.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Thrall RS, Phan SH, McCormick JR and Ward
PA: The development of bleomycin-induced pulmonary fibrosis in
neutrophil-depleted and complement-depleted rats. Am J Pathol.
105:76–81. 1981.PubMed/NCBI
|
|
40
|
Rubin P, Finkelstein J and Shapiro D:
Molecular biology mechanisms in the radiation induction of
pulmonary injury syndromes: Interrelationship between the alveolar
macrophage and the septal fibroblast. Int J Radiat Oncol Biol Phys.
24:93–101. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Cai X, Fang Z, Dou J, Yu A and Zhai G:
Bioavailability of quercetin: Problems and promises. Curr Med Chem.
20:2572–2582. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Liu H, Xue JX, Li X, Ao R and Lu Y:
Quercetin liposomes protect against radiation-induced pulmonary
injury in a murine model. Onocl Lett. 6:453–459. 2013.
|
|
43
|
Suarez S and Hickey AJ: Drug properties
affecting aerosol behavior. Respir Care. 45:652–666.
2000.PubMed/NCBI
|
|
44
|
Hrvacić B, Bosnjak B, Tudja M, Mesić M and
Merćep M: Applicability of an ultrasonic nebulization system for
the airways delivery of beclomethasone dipropionate in a murine
model of asthma. Pharm Res. 23:1765–1775. 2006. View Article : Google Scholar : PubMed/NCBI
|
