Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
January-2018 Volume 15 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2018 Volume 15 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature

  • Authors:
    • Ji‑Ping Huo
    • Cui Liu
    • Bei‑Bei Jin
    • Feng‑Xia Duan
    • Sheng‑Hui Mei
    • Xin‑Gang Li
    • Zhi‑Gang Zhao
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacy, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing 100050, P.R. China, Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China, Department of Respiratory Medicine, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing 100050, P.R. China, Department of Ultrasonography, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing 100050, P.R. China
    Copyright: © Huo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 39-46
    |
    Published online on: October 30, 2017
       https://doi.org/10.3892/etm.2017.5393
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Cryptogenic organizing pneumonia (COP) is a rare pulmonary disorder of unknown etiology. COP with hemoptysis as the primary presenting symptom has rarely been reported. The present study reported a case of COP that resembled lung carcinoma with hemoptysis as the only clinical symptom. The patient recovered well following thoracoscope surgery. A literature review of 119 COP cases between 1995 and 2015 was presented. Cough, fever and dyspnea were the most common clinical manifestations. The most common imaging manifestations were multiple or single consolidation, lung nodules, migratory sign, reversed halo sign, and multiple ground‑glass opacity. A total of 3 cases exhibited COP accompanied by lung cancer. Glucocorticoids were effective for the majority of cases and invasive surgeries were implemented in most cases. The majority of cases recovered or relieved, and the prognosis of COP was relatively good. COP was easily confused with lung tumor and it is necessary to make differential diagnosis between COP and lung cancer. Invasive surgery should be avoided when possible to avoid or reduce patient trauma.
View Figures

Figure 1

Figure 2

View References

1 

Ding QL, Lv D, Wang BJ, Zhang QL, Yu YM, Sun SF, Chen ZB, Ma HY and Deng ZC: Macrolide therapy in cryptogenic organizing pneumonia: A case report and literature review. Exp Ther Med. 9:829–834. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Narasimhaiah DH, Chakravorty I, Swamy R and Prakash D: Organising pneumonia presenting as acute life threatening pulmonary haemorrhage. BMJ Case Rep. 2011:pii: bcr03200916892011. View Article : Google Scholar

3 

Zhao F, Yan SX, Wang GF, Wang J, Lu PX, Chen B, Yuan J, Zhang SZ and Wang YX: CT features of focal organizing pneumonia: An analysis of consecutive histopathologically confirmed 45 cases. Eur J Radiol. 83:73–78. 2014. View Article : Google Scholar : PubMed/NCBI

4 

Epler GR, Colby TV, McLoud TC, Carrington CB and Gaensler EA: Bronchiolitis obliterans organizing pneumonia. N Engl J Med. 312:152–158. 1985. View Article : Google Scholar : PubMed/NCBI

5 

Radzikowska E, Nowicka U, Wiatr E, Jakubowska L, Langfort R, Chabowski M and Roszkowski K: Organising pneumonia and lung cancer - case report and review of the literature. Pneumonol Alergol Pol. 75:394–397. 2007.PubMed/NCBI

6 

Melloni G, Cremona G, Bandiera A, Arrigoni G, Rizzo N, Varagona R, Muriana G, Carretta A, Ciriaco P, Canneto B and Zannini P: Localized organizing pneumonia: Report of 21 cases. Ann Thorac Surg. 83:1946–1951. 2007. View Article : Google Scholar : PubMed/NCBI

7 

Xie S, Shen C, Zhang Y, Lu K, Hu F, Tan M, Lin H, Xu L, Yuan Q, Song X and Wang C: Cryptogenic organizing pneumonia associated with invasive pulmonary aspergillosis: A case report and review of the literature. Int J Clin Exp Pathol. 7:8637–8646. 2014.PubMed/NCBI

8 

Sanito NJ, Morley TF and Condoluci DV: Bronchiolitis obliterans organizing pneumonia in an AIDS patient. Eur Respir J. 8:1021–1024. 1995.PubMed/NCBI

9 

Haro M, Vizcaya M, Texidó A, Aguilar X and Arevalo M: Idiopathic bronchiolitis obliterans organizing pneumonia with multiple cavitary lung nodules. Eur Respir J. 8:1975–1977. 1995. View Article : Google Scholar : PubMed/NCBI

10 

Pérez de Llano LA, Soilán JL, García Pais MJ, Mata I, Moreda M and Laserna B: Idiopathic bronchiolitis obliterans with organizing pneumonia presenting with adult respiratory distress syndrome. Respir Med. 92:884–886. 1998. View Article : Google Scholar : PubMed/NCBI

11 

Stey C, Truninger K, Marti D, Vogt P and Medici TC: Bronchiolitis obliterans organizing pneumonia associated with polymyalgia rheumatica. Eur Respir J. 13:926–929. 1999. View Article : Google Scholar : PubMed/NCBI

12 

Alcolea S, Santiago Recuerda A and Prados MC: Cryptogenic organizing pneumonia and mediastinal lymphadenopathy. Arch Bronconeumol. 40:3842004.(In Spanish). View Article : Google Scholar : PubMed/NCBI

13 

Arrabal S, ánchez R, Mongil Poce R, Benítez Doménech A, Fernández de Rota Avecilla A and Fernández Bermúdez JL: Bronchiolitis obliterans organizing pneumonia and bronchogenic carcinoma coexisting in different parts of the lungs. Arch Bronconeumol. 40:141–143. 2004.(In Spanish). View Article : Google Scholar : PubMed/NCBI

14 

Husain SJ, Irfan M, Zubairi AS and Salahuddin N: Rapidly-progressive bronchiolitis obliterans organising pneumonia. Singapore Med J. 45:283–285. 2004.PubMed/NCBI

15 

Hooi LN: Bronchiolitis obliterans organising pneumonia: A treatable condition. Med J Malaysia. 60:222–225. 2005.PubMed/NCBI

16 

Burke L and Jacob BK: Reversed halo sign in cryptogenic organising pneumonia. BMJ Case Rep. 2010:pii: bcr03201028242010. View Article : Google Scholar

17 

Maimon N: A 47-year-old female with shortness of breath and ‘reversed halo sign’. Eur Respir Rev. 19:83–85. 2010. View Article : Google Scholar : PubMed/NCBI

18 

Eguchi T, Takasuna K, Fujiwara M and Yoshida K: Coexistence of a pulmonary adenocarcinoma with a focal organizing pneumonia. Interact Cardiovasc Thorac Surg. 13:444–446. 2011. View Article : Google Scholar : PubMed/NCBI

19 

Lee J, Cha SI, Park TI, Park JY, Jung TH and Kim CH: Adjunctive effects of cyclosporine and macrolide in rapidly progressive cryptogenic organizing pneumonia with no prompt response to steroid. Intern Med. 50:475–479. 2011. View Article : Google Scholar : PubMed/NCBI

20 

Pardo J, Panizo A, Sola I, Queipo F, Martinez-Peñuela A and Carias R: Prognostic value of clinical, morphologic, and immunohistochemical factors in patients with bronchiolitis obliterans-organizing pneumonia. Hum Pathol. 44:718–724. 2013. View Article : Google Scholar : PubMed/NCBI

21 

Sheikh IA, Saadia N, Sheikh N and Culpepper-Morgan JA: Simultaneous diagnosis of cryptogenic organizing pneumonia and HIV in a 45 year old man. Am J Case Rep. 13:166–168. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Terada T: Autopsy findings of fatal cryptogenic organizing pneumonia. Int J Clin Exp Pathol. 6:1128–1131. 2013.PubMed/NCBI

23 

Utrilla Contreras C, Fernández-Velilla Peña M, García Río F and Torres Sánchez MI: Radiographic patterns in the diagnostic approach to organizing pneumonia. Rev Clin Esp (Barc). 214:258–265. 2014.(In English, Spanish). View Article : Google Scholar : PubMed/NCBI

24 

Sugiura K, Muro Y and Akiyama M: Solitary organizing pneumonia mimicking lung adenocarcinoma in systemic sclerosis. Arthritis Rheumatol. 66:26482014. View Article : Google Scholar : PubMed/NCBI

25 

Zannoni S, Lorenzi C, Paoli M, Orso F, Torrini M, Rafanelli M, Toffanello G, Giordano A, Gori Sacco FC, Marchionni N and Ungar A: P-263: Cryptogenic organizing pneumonia: A rare syndrome even in the elderly. Case report. Eur Geriatr Med. 6 Suppl 1:S1022015. View Article : Google Scholar

26 

Nakahara Y, Oonishi Y, Takiguchi J, Morimoto A, Matsuoka K, Imanishi N, Higashino T, Mimura R, Kawamura T and Mochiduki Y: Nontuberculous mycobacterial lung disease accompanied by organizing pneumonia. Intern Med. 54:945–951. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Morichika D, Miyahara N, Hotta K, Okamoto Y, Minami D, Irie M, Tanimoto Y, Kanehiro A, Tanimoto M and Kiura K: Invasive mucinous adenocarcinoma mimicking organizing pneumonia associated with mycobacterium fortuitum infection. Intern Med. 53:2795–2799. 2014. View Article : Google Scholar : PubMed/NCBI

28 

National Comprehensive Cancer Network, . NCCN clinical practice guidelines in Oncology: Lung Cancer Screening (Version 2.2015). https://www.nccn.org/professionals/physician_gls/f_guidelines.aspMarch 17–2015

29 

Feng AN, Cai HR, Zhou Q, Zhang YF and Meng FQ: Diagnostic problems related to acute fibrinous and organizing pneumonia: Misdiagnosis in 2 cases of lung consolidation and occupying lesions. Int J Clin Exp Pathol. 7:4493–4497. 2014.PubMed/NCBI

30 

Travis WD, Costabel U, Hansell DM, King TE Jr, Lynch DA, Nicholson AG, Ryerson CJ, Ryu JH, Selman M, Wells AU, et al: An Official American Thoracic Society/European Respiratory Society Statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med. 188:733–748. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Baque-Juston M, Pellegrin A, Leroy S, Marquette CH and Padovani B: Organizing pneumonia: What is it? A conceptual approach and pictorial review. Diagn Interv Imaging. 95:771–777. 2014. View Article : Google Scholar : PubMed/NCBI

32 

Zhao ZR, Li Z, Situ DR and Ng CS: Recent clinical innovations in thoracic surgery in Hong Kong. J Thorac Dis. 8 Suppl 8:S618–S626. 2016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Huo JP, Liu C, Jin BB, Duan FX, Mei SH, Li XG and Zhao ZG: Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature. Exp Ther Med 15: 39-46, 2018.
APA
Huo, J., Liu, C., Jin, B., Duan, F., Mei, S., Li, X., & Zhao, Z. (2018). Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature. Experimental and Therapeutic Medicine, 15, 39-46. https://doi.org/10.3892/etm.2017.5393
MLA
Huo, J., Liu, C., Jin, B., Duan, F., Mei, S., Li, X., Zhao, Z."Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature". Experimental and Therapeutic Medicine 15.1 (2018): 39-46.
Chicago
Huo, J., Liu, C., Jin, B., Duan, F., Mei, S., Li, X., Zhao, Z."Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature". Experimental and Therapeutic Medicine 15, no. 1 (2018): 39-46. https://doi.org/10.3892/etm.2017.5393
Copy and paste a formatted citation
x
Spandidos Publications style
Huo JP, Liu C, Jin BB, Duan FX, Mei SH, Li XG and Zhao ZG: Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature. Exp Ther Med 15: 39-46, 2018.
APA
Huo, J., Liu, C., Jin, B., Duan, F., Mei, S., Li, X., & Zhao, Z. (2018). Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature. Experimental and Therapeutic Medicine, 15, 39-46. https://doi.org/10.3892/etm.2017.5393
MLA
Huo, J., Liu, C., Jin, B., Duan, F., Mei, S., Li, X., Zhao, Z."Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature". Experimental and Therapeutic Medicine 15.1 (2018): 39-46.
Chicago
Huo, J., Liu, C., Jin, B., Duan, F., Mei, S., Li, X., Zhao, Z."Cryptogenic organizing pneumonia masquerading as lung carcinoma: A case report and review of the literature". Experimental and Therapeutic Medicine 15, no. 1 (2018): 39-46. https://doi.org/10.3892/etm.2017.5393
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team