Efficacy of arthroscopic loose body removal for knee osteoarthritis

Zhao,Baoxiang; Yu,Yibo; Liu,Wenquan; Du,Jian

doi:10.3892/etm.2017.5564

February-2018 Volume 15 Issue 2

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February-2018 Volume 15 Issue 2

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Article

Efficacy of arthroscopic loose body removal for knee osteoarthritis

Authors:
- Baoxiang Zhao
- Yibo Yu
- Wenquan Liu
- Jian Du
View Affiliations / Copyright

Affiliations: Department of Orthopaedics, Linyi People's Hospital, Linyi, Shandong 276000, P.R. China, Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China, Department of Orthopaedics, Chinese Medicine Hospital in Linyi City, Linyi, Shandong 276002, P.R. China, Department of Orthopaedics, Lanshan District People's Hospital, Linyi, Shandong 276000, P.R. China
Pages: 1666-1671
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Published online on: November 24, 2017

https://doi.org/10.3892/etm.2017.5564
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Abstract

The purpose of the present study was to explore the efficacy of arthroscopic loose body removal for knee osteoarthritis (KOA). A total of 23 patients with KOA were enrolled and randomly received conservative treatment (conservative group; n=10) or loose body removal surgery (surgery group; n=13). The serum levels of disease activity indices, including hypersensitive C‑reactive protein (hs‑CRP), erythrocyte sedimentation rate (ESR) and synovial inflammatory factors [interleukin (IL)‑1 and IL‑6] were detected prior to surgery, and at 4 days, 2 or 4 weeks after surgery. All patients were followed up for 2 years and the cure rate was estimated. No significant difference was identified in pre‑operative plasma levels of hs‑CRP and ESR as well as the synovial concentration of IL‑1 and IL‑6 between the two groups (all P>0.05). At 2 and 4 weeks after treatment, the levels of these parameters in the surgery group were significantly lower than those in the conservative group (all P<0.05), although the maximum value of these parameters was higher in the surgery group than in the conservative group at 4 days after surgery. The cure rate for KOA in the surgery group was significantly higher than that in the conservative group. In conclusion, the results demonstrated that arthroscopic loose body removal is a more effective treatment than conservative therapy for KOA.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Efficacy of arthroscopic loose body removal for knee osteoarthritis

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Abstract

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