|
1
|
Gil HW, Hong JR, Jang SH and Hong SY:
Diagnostic and therapeutic approach for acute paraquat
intoxication. J Korean Med Sci. 29:1441–1449. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Xu L, Xu J and Wang Z: Molecular
mechanisms of paraquat-induced acute lung injury: A current review.
Drug Chem Toxicol. 37:130–134. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Dinis-Oliveira RJ, Duarte JA,
Sanchez-Navarro A, Remiao F, Bastos ML and Carvalho F: Paraquat
poisonings: Mechanisms of lung toxicity, clinical features, and
treatment. Crit Rev Toxicol. 38:13–71. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Nieto MA, Huang RY, Jackson RA and Thiery
JP: EMT: 2016. Cell. 166:21–45. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Stone RC, Pastar I, Ojeh N, Chen V, Liu S,
Garzon KI and Tomic-Canic M: Epithelial-mesenchymal transition in
tissue repair and fibrosis. Cell Tissue Res. 365:495–506. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Bartis D, Mise N, Mahida RY, Eickelberg O
and Thickett DR: Epithelial-mesenchymal transition in lung
development and disease: Does it exist and is it important? Thorax.
69:760–765. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kage H and Borok Z: EMT and interstitial
lung disease: A mysterious relationship. Curr Opin Pulm Med.
18:517–523. 2012.PubMed/NCBI
|
|
8
|
Wang J, Zhu Y, Tan J, Meng X, Xie H and
Wang R: Lysyl oxidase promotes epithelial-to-mesenchymal transition
during paraquat-induced pulmonary fibrosis. Mol Biosyst.
12:499–507. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhu Y, Tan J, Xie H, Wang J, Meng X and
Wang R: HIF-1alpha regulates EMT via the Snail and beta-catenin
pathways in paraquat poisoning-induced early pulmonary fibrosis. J
Cell Mol Med. 20:688–697. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Masoud GN and Li W: HIF-1alpha pathway:
Role, regulation and intervention for cancer therapy. Acta Pharm
Sin B. 5:378–389. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Balamurugan K: HIF-1 at the crossroads of
hypoxia, inflammation, and cancer. Int J Cancer. 138:1058–1066.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Zhou G, Dada LA, Wu M, Kelly A, Trejo H,
Zhou Q, Varga J and Sznajder JI: Hypoxia-induced alveolar
epithelial-mesenchymal transition requires mitochondrial ROS and
hypoxia-inducible factor 1. Am J Physiol Lung Cell Mol Physiol.
297:L1120–1130. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Darby IA and Hewitson TD: Hypoxia in
tissue repair and fibrosis. Cell Tissue Res. 365:553–562. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wang RL, Tang X, Wu X, Xu R, Yu KL and Xu
K: The relationship between HIF-1α expression and the early lung
fibrosis in rats with acute paraquat poisoning. Zhonghua Lao Dong
Wei Sheng Zhi Ye Bing Za Zhi. 30:273–277. 2012.(In Chinese).
PubMed/NCBI
|
|
15
|
Cox TR, Bird D, Baker AM, Barker HE, Ho
MW, Lang G and Erler JT: LOX-mediated collagen crosslinking is
responsible for fibrosis-enhanced metastasis. Cancer Res.
73:1721–1732. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lopez B, Gonzalez A, Hermida N, Valencia
F, de Teresa E and Diez J: Role of lysyl oxidase in myocardial
fibrosis: From basic science to clinical aspects. Am J Physiol
Heart Circ Physiol. 299:H1–9. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Deng S, Jin T, Zhang L, Bu H and Zhang P:
Mechanism of tacrolimus-induced chronic renal fibrosis following
transplantation is regulated by ox-LDL and its receptor, LOX-1. Mol
Med Rep. 14:4124–4134. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Cheng T, Liu Q, Zhang R, Zhang Y, Chen J,
Yu R and Ge G: Lysyl oxidase promotes bleomycin-induced lung
fibrosis through modulating inflammation. J Mol Cell Biol.
6:506–515. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Erler JT, Bennewith KL, Nicolau M,
Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS and Giaccia AJ:
Lysyl oxidase is essential for hypoxia-induced metastasis. Nature.
440:1222–1226. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ji F, Wang Y, Qiu L, Li S, Zhu J, Liang Z,
Wan Y and Di W: Hypoxia inducible factor 1α-mediated LOX expression
correlates with migration and invasion in epithelial ovarian
cancer. Int J Oncol. 42:1578–1588. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Pez F, Dayan F, Durivault J, Kaniewski B,
Aimond G, Le Provost GS, Deux B, Clézardin P, Sommer P, Pouysségur
J and Reynaud C: The HIF-1-inducible lysyl oxidase activates HIF-1
via the Akt pathway in a positive regulation loop and synergizes
with HIF-1 in promoting tumor cell growth. Cancer Res.
71:1647–1657. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-tie quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Lamouille S, Xu J and Derynck R: Molecular
mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell
Biol. 15:178–196. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
24
|
Elvidge GP, Glenny L, Appelhoff RJ,
Ratcliffe PJ, Ragoussis J and Gleadle JM: Concordant regulation of
gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase
inhibition: The role of HIF-1alpha, HIF-2alpha, and other pathways.
J Biol Chem. 281:15215–15226. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Goto TM, Arima Y, Nagano O and Saya H:
Lysyl oxidase is induced by cell density-mediated cell cycle
suppression via RB-E2F1-HIF-1α axis. Cell Struct Funct. 38:9–14.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Yang X, Li S, Li W, Chen J, Xiao X, Wang
Y, Yan G and Chen L: Inactivation of lysyl oxidase by
β-aminopropionitrile inhibits hypoxia-induced invasion and
migration of cervical cancer cells. Oncol Rep. 29:541–548. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Wang Y, Ma J, Shen H, Wang C, Sun Y,
Howell SB and Lin X: Reactive oxygen species promote ovarian cancer
progression via the HIF-1α/LOX/E-cadherin pathway. Oncol Rep.
32:2150–2158. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Reynaud C, Ferreras L, Di Mauro P, Kan C,
Croset M, Bonnelye E, Pez F, Thomas C, Aimond G, Karnoub AE, et al:
Lysyl oxidase is a strong determinant of tumor cell colonization in
bone. Cancer Res. 77:268–278. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Schietke R, Warnecke C, Wacker I, Schödel
J, Mole DR, Campean V, Amann K, Goppelt-Struebe M, Behrens J,
Eckardt KU and Wiesener MS: The lysyl oxidases LOX and LOXL2 are
necessary and sufficient to repress E-cadherin in hypoxia: Insights
into cellular transformation processes mediated by HIF-1. J Biol
Chem. 285:6658–6669. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zeisberg M and Neilson EG: Biomarkers for
epithelial-mesenchymal transitions. J Clin Invest. 119:1429–1437.
2009. View
Article : Google Scholar : PubMed/NCBI
|
|
31
|
Xu L, Cui WH, Zhou WC, Li DL, Li LC, Zhao
P, Mo XT, Zhang Z and Gao J: Activation of Wnt/β-catenin signalling
is required for TGF-β/Smad2/3 signalling during myofibroblast
proliferation. J Cell Mol Med. 21:1545–1554. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ji S, Deng H, Jin W, Yan P, Wang R, Pang
L, Zhou J, Zhang J, Chen X, Zhao X and Shen J: Beta-catenin
participates in dialysate-induced peritoneal fibrosis via enhanced
peritoneal cell epithelial-to-mesenchymal transition. FEBS Open
Bio. 7:265–273. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wang X, Dai W, Wang Y, Gu Q, Yang D and
Zhang M: Blocking the Wnt/β-catenin pathway by lentivirus-mediated
short hairpin RNA targeting β-catenin gene suppresses
silica-induced lung fibrosis in mice. Int J Environ Res Public
Health. 12:10739–10754. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Martinez-Martinez E, Ibarrola J, Calvier
L, Fernandez-Celis A, Leroy C, Cachofeiro V, Rossignol P and
Lopez-Andres N: Galectin-3 blockade reduces renal fibrosis in two
normotensive experimental models of renal damage. PLoS One.
11:e01662722016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Hu BL, Shi C, Lei RE, Lu DH, Luo W, Qin
SY, Zhou Y and Jianga HX: Interleukin-22 ameliorates liver fibrosis
through miR-200a/beta-catenin. Sci Rep. 6:364362016. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Lin JC, Kuo WW, Baskaran R, Chen MC, Ho
TJ, Chen RJ, Chen YF, Vijaya Padma V, Lay IS and Huang CY:
Enhancement of beta-catenin in cardiomyocytes suppresses survival
protein expression but promotes apoptosis and fibrosis. Cardiol J.
24:195–205. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Anastas JN and Moon RT: WNT signalling
pathways as therapeutic targets in cancer. Nat Rev Cancer.
13:11–26. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Xie H, Tan JT, Wang RL, Meng XX, Tang X
and Gao S: Expression and significance of HIF-1alpha in pulmonary
fibrosis induced by paraquat. Exp Biol Med (Maywood).
238:1062–1068. 2013. View Article : Google Scholar : PubMed/NCBI
|
