Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
May-2018 Volume 15 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2018 Volume 15 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2

  • Authors:
    • Yanxia Zhu
    • Xiaofang Wang
    • Weihua Wang
    • Hongguang Wang
    • Fenglei Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, People's Hospital of Dongying, Dongying, Shandong 257091, P.R. China, Department of Emergency, People's Hospital of Dongying, Dongying, Shandong 257091, P.R. China
    Copyright: © Zhu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 4395-4399
    |
    Published online on: March 6, 2018
       https://doi.org/10.3892/etm.2018.5930
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study investigated the clinical significance of changes in levels of hypersensitive plasma pentraxin-3 (PTX3), hemoglobin A1c (HbAlc) and apolipoprotein A-I (ApoA1)/apolipoprotein B (ApoB) on patients with acute myocardial infarction (AMI) and diabetes mellitus type 2 (T2DM). After admission, 100 patients diagnosed with AMI combined with T2DM were selected as Group A. According to the level of fasting blood glucose (FBG), they were then subdivided into Group A1 (n=44) with FBG ≥13.0 mmol/l and Group A2 (n=56) with FBG <13.0 mmol/l. A total of 100 hospitalized patients with AMI in People's Hospital of Dongying (Dongying, China) were collected as Group B, and 100 healthy people receiving physical examination in the Physical Examination Center of People's Hospital of Dongying were selected as Group C. Serum PTX3, HbAlc and ApoA1/ApoB of all the study participants were tested, and diseased coronary artery vessels were divided into single-, double- and triple-vessel lesions according to their numbers. Logistic regression analysis was performed for the number of diseased coronary artery vessels and each index. The level of PTX3 in Group A1 was higher than that in Group A2; the level of ApoA1/ApoB in the former was lower than that in the latter (p<0.05); and the level of HbAlc in the former was significantly higher than that in the latter (p<0.01); the levels of PTX3 and HbA1c in Group A2 were higher than those in Group B, while the level of ApoA1/ApoB in the former was lower than that in the latter (p<0.05). Logistic regression analysis showed that the number of diseased coronary artery vessels was positively correlated with PTX3 and HbA1c, but negatively correlated with ApoA1/ApoB. PTX3, HbAlc and ApoA1/apoB have a certain clinical significance in assessing the severity of AMI combined with T2DM.
View Figures
View References

1 

Tillmann T, Vaucher J, Okbay A, Pikhart H, Peasey A, Kubinova R, Pajak A, Tamosiunas A, Malyutina S, Hartwig FP, et al: Education and coronary heart disease: Mendelian randomisation study. BMJ. 358:j35422017. View Article : Google Scholar : PubMed/NCBI

2 

Gilani N, Kazemnejad A, Zayeri F, Hadaegh F, Azizi F and Khalili D: Anthropometric indices as predictors of coronary heart disease risk: Joint modeling of longitudinal measurements and time to event. Iran J Public Health. 46:1546–1554. 2017.PubMed/NCBI

3 

Chen L, Wei B, Xu L and Wu Y: The association of inflammatory markers and periodontal indexes with the risk of coronary heart disease in Chinese patients with type 2 diabetes mellitus. Diabetes Res Clin Pract. 135:37–44. 2017. View Article : Google Scholar : PubMed/NCBI

4 

Kang HC and Hong JS: Association between costs and quality of acute myocardial infarction care hospitals under the Korea National Health Insurance program. Medicine (Baltimore). 96:e76222017. View Article : Google Scholar : PubMed/NCBI

5 

Yavuz B, Kabakci G, Aksoy H, Tulumen E, Deveci OS, Aytemir K, Tokgozoglu L, Ozkutlu H, Nazli N and Oto A: Determining the relationship between metabolic syndrome score and angiographic severity of coronary artery disease. Int J Clin Pract. 62:717–722. 2008. View Article : Google Scholar : PubMed/NCBI

6 

Wang J, Wu X, Li Y, Han X, Hu H, Wang F, Yu C, Li X, Yang K, Yuan J, et al: Serum bilirubin concentrations and incident coronary heart disease risk among patients with type 2 diabetes: The Dongfeng-Tongji cohort. Acta Diabetol. 54:257–264. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Farrokhian A, Bahmani F, Taghizadeh M, Mirhashemi SM, Aarabi MH, Raygan F, Aghadavod E and Asemi Z: Selenium supplementation affects insulin resistance and serum hs-CRP in patients with type 2 diabetes and coronary heart disease. Horm Metab Res. 48:263–268. 2016. View Article : Google Scholar : PubMed/NCBI

8 

Ahmad S, Xue Z, Silverman A and Lindsay J: Complexity of the relation between hemoglobin A1C, diabetes mellitus, and progression of coronary narrowing in postmenopausal women. Am J Cardiol. 111:793–799. 2013. View Article : Google Scholar : PubMed/NCBI

9 

Zhang J, Koussih L, Shan L, Halayko AJ, Chen BK and Gounni AS: TNF up-regulates Pentraxin3 expression in human airway smooth muscle cells via JNK and ERK1/2 MAPK pathways. Allergy Asthma Clin Immunol. 11:372015. View Article : Google Scholar : PubMed/NCBI

10 

Lu M, Lu Q, Zhang Y and Tian G: ApoB/apoA1 is an effective predictor of coronary heart disease risk in overweight and obesity. J Biomed Res. 25:266–273. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Claesson R, Ekelund M, Ignell C and Berntorp K: Role of HbA1c in post-partum screening of women with gestational diabetes mellitus. J Clin Transl Endocrinol. 2:21–25. 2014. View Article : Google Scholar : PubMed/NCBI

12 

National standards of P.R.C. Diagnostic Criteria of Coronary Atherosclerotic Heart Disease. Beijing: Quality Inspection Press of China 1–4; 2010

13 

Deckers JG, Schellevis FG and Fleming DM: WHO diagnostic criteria as a validation tool for the diagnosis of diabetes mellitus: A study in five European countries. Eur J Gen Pract. 12:108–113. 2006. View Article : Google Scholar : PubMed/NCBI

14 

de Kreutzenberg Vigili S, Solini A, Vitolo E, Boi A, Bacci S, Cocozza S, Nappo R, Rivellese A, Avogaro A and Baroni MG: Silent coronary heart disease in patients with type 2 diabetes: Application of a screening approach in a follow-up study. J Diabetes Complications. 31:952–957. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Emdin CA, Klarin D, Natarajan P, Florez JC, Kathiresan S and Khera AV and Khera AV: CARDIOGRAM Exome Consortium: Genetic variation at the sulfonylurea receptor, type 2 diabetes, and coronary heart disease. Diabetes. 66:2310–2315. 2017. View Article : Google Scholar : PubMed/NCBI

16 

Naito A, Tanabe N, Jujo T, Shigeta A, Sugiura T, Sakao S, Ishida K and Tatsumi K: Pentraxin3 in chronic thromboembolic pulmonary hypertension: A new biomarker for screening from remitted pulmonary thromboembolism. PLoS One. 9:e1130862014. View Article : Google Scholar : PubMed/NCBI

17 

Tarantino U, Feola M, Celi M and Scimeca M: PTX3: A new mediator of bone metabolism and osteoporosis. Muscles Ligaments Tendons J. 7:200–201. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Ohde S, Deshpande GA, Yokomichi H, Takahashi O, Fukui T and Yamagata Z: HbA1c monitoring interval in patients on treatment for stable type 2 diabetes. A ten-year retrospective, open cohort study. Diabetes Res Clin Pract. 135:166–171. 2018. View Article : Google Scholar : PubMed/NCBI

19 

Hansel B, Giral P, Gambotti L, Lafourcade A, Peres G, Filipecki C, Kadouch D, Hartemann A, Oppert JM, Bruckert E, et al: A fully automated web-based program improves lifestyle habits and HbA1c in patients with type 2 diabetes and abdominal obesity: Randomized trial of patient E-coaching nutritional support (The ANODE Study). J Med Internet Res. 19:e3602017. View Article : Google Scholar : PubMed/NCBI

20 

Mousavi SN, Kamali K, Mirbazel M and Jameshorani M, Mousavi N, Kamali K, Mirbazel M and Jameshorani M: The best cut-off value for HbA1c as a screening tool in Iranian women with gestational diabetes mellitus. J Family Reprod Health. 11:37–42. 2017.PubMed/NCBI

21 

Jiang J, Zhao L, Lin L, Gui M, Aleteng Q, Wu B, Wang S, Pan B, Ling Y and Gao X: Postprandial blood glucose outweighs fasting blood glucose and HbA1c in screening coronary heart disease. Sci Rep. 7:142122017. View Article : Google Scholar : PubMed/NCBI

22 

Trivedi H, Gray LJ, Seidu S, Davies MJ, Charpentier G, Lindblad U, Kellner C, Nolan J, Pazderska A, Rutten G, et al: Self-knowledge of HbA1c in people with type 2 diabetes mellitus and its association with glycaemic control. Prim Care Diabetes. 11:414–420. 2017. View Article : Google Scholar : PubMed/NCBI

23 

Bays HE, Shah A, Lin J, Sisk CM, Dong Q and Maccubbin D: Consistency of extended-release niacin/laropiprant effects on Lp(a), ApoB, non-HDL-C, Apo A1, and ApoB/ApoA1 ratio across patient subgroups. Am J Cardiovasc Drugs. 12:197–206. 2012. View Article : Google Scholar : PubMed/NCBI

24 

Zheng J, Yin Q, Cao J and Zhang B: Obesity contributes more to increasing ApoB/ApoA1 ratio than hyperandrogenism in PCOS women aged 20–38 years in China. Exp Ther Med. 13:1337–1342. 2017. View Article : Google Scholar : PubMed/NCBI

25 

Öhman M, Öhman ML and Wållberg-Jonsson S: The apoB/apoA1 ratio predicts future cardiovascular events in patients with rheumatoid arthritis. Scand J Rheumatol. 43:259–264. 2014. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhu Y, Wang X, Wang W, Wang H and Zhang F: Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2. Exp Ther Med 15: 4395-4399, 2018.
APA
Zhu, Y., Wang, X., Wang, W., Wang, H., & Zhang, F. (2018). Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2. Experimental and Therapeutic Medicine, 15, 4395-4399. https://doi.org/10.3892/etm.2018.5930
MLA
Zhu, Y., Wang, X., Wang, W., Wang, H., Zhang, F."Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2". Experimental and Therapeutic Medicine 15.5 (2018): 4395-4399.
Chicago
Zhu, Y., Wang, X., Wang, W., Wang, H., Zhang, F."Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2". Experimental and Therapeutic Medicine 15, no. 5 (2018): 4395-4399. https://doi.org/10.3892/etm.2018.5930
Copy and paste a formatted citation
x
Spandidos Publications style
Zhu Y, Wang X, Wang W, Wang H and Zhang F: Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2. Exp Ther Med 15: 4395-4399, 2018.
APA
Zhu, Y., Wang, X., Wang, W., Wang, H., & Zhang, F. (2018). Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2. Experimental and Therapeutic Medicine, 15, 4395-4399. https://doi.org/10.3892/etm.2018.5930
MLA
Zhu, Y., Wang, X., Wang, W., Wang, H., Zhang, F."Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2". Experimental and Therapeutic Medicine 15.5 (2018): 4395-4399.
Chicago
Zhu, Y., Wang, X., Wang, W., Wang, H., Zhang, F."Expression and influence of pentraxin-3, HbAlc and ApoA1/ApoB in serum of patients with acute myocardial infarction combined with diabetes mellitus type 2". Experimental and Therapeutic Medicine 15, no. 5 (2018): 4395-4399. https://doi.org/10.3892/etm.2018.5930
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team