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Article

Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction

  • Authors:
    • Wenyuan Xu
    • Ning Xie
    • Cheng Zhang
    • Qin Huang
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China
  • Pages: 4564-4570
    |
    Published online on: March 19, 2018
       https://doi.org/10.3892/etm.2018.5965
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Abstract

The current study aimed to investigate the imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction. In total, 84 patients diagnosed with acute cerebral infarction were recruited. Magnetic resonance angiography was performed to detect the existence of intracranial artery stenosis or occlusion. In addition, magnetic resonance imaging and diffusion weighted imaging were employed to analyze the infarction types and characteristics. In the majority of patients, the infarction resulted from internal carotid stenosis (77 cases; 91.7%), while it was caused by vertebral artery stenosis in a small number of cases (7 cases; 8.3%). Multiple infarction was identified the most common type of infarction among all cases (69.0%). The most common types of infarctions in the internal carotid system were multiple infarction implicating both the cortex and centrum ovale (23.4%), and internal watershed infarction (22.1%). Although the number of cases was relatively small, multiple infarction was observed to have a high incidence in the vertebral artery system. Bedside electrocardiogram was also recorded to determine the sinus rhythm and examine the abnormal hemodynamics. The sinus bradycardia rate of patients with multiple infarction was markedly greater in comparison with that in single infarction patients (χ2=0.01, P<0.05). Transcranial Doppler plus microembolus monitoring was utilized to explore the possible pathogenesis of all types of infarctions, such as arterial embolization. As compared with the single infarction patients, the embolus rate in patients with multiple infarction was notably increased by ~3.7‑fold (χ2=8.65, P<0.05). In conclusion, the cerebral infarction was common in the internal carotid system, with multiple infarction observed in the majority of cases. The pathogenesis of cerebral infarction included arterial embolization and inadequate hemoperfusion.
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Copy and paste a formatted citation
Spandidos Publications style
Xu W, Xie N, Zhang C and Huang Q: Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction. Exp Ther Med 15: 4564-4570, 2018.
APA
Xu, W., Xie, N., Zhang, C., & Huang, Q. (2018). Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction. Experimental and Therapeutic Medicine, 15, 4564-4570. https://doi.org/10.3892/etm.2018.5965
MLA
Xu, W., Xie, N., Zhang, C., Huang, Q."Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction". Experimental and Therapeutic Medicine 15.5 (2018): 4564-4570.
Chicago
Xu, W., Xie, N., Zhang, C., Huang, Q."Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction". Experimental and Therapeutic Medicine 15, no. 5 (2018): 4564-4570. https://doi.org/10.3892/etm.2018.5965
Copy and paste a formatted citation
x
Spandidos Publications style
Xu W, Xie N, Zhang C and Huang Q: Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction. Exp Ther Med 15: 4564-4570, 2018.
APA
Xu, W., Xie, N., Zhang, C., & Huang, Q. (2018). Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction. Experimental and Therapeutic Medicine, 15, 4564-4570. https://doi.org/10.3892/etm.2018.5965
MLA
Xu, W., Xie, N., Zhang, C., Huang, Q."Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction". Experimental and Therapeutic Medicine 15.5 (2018): 4564-4570.
Chicago
Xu, W., Xie, N., Zhang, C., Huang, Q."Imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction". Experimental and Therapeutic Medicine 15, no. 5 (2018): 4564-4570. https://doi.org/10.3892/etm.2018.5965
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