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Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis

  • Authors:
    • Suxia Zhang
    • Qian Sun
    • Xiaojuan Jiang
    • Fengchun Gao
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics, Jinan Maternity and Child Care Hospital, Jinan, Shandong 250001, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 4901-4905
    |
    Published online on: March 27, 2018
       https://doi.org/10.3892/etm.2018.5998
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Abstract

The clinical significance of hsa-mir-1247 and hsa‑mir-1269a expression in ectopic pregnancy due to salpingitis was investigated. Eighty patients with ectopic pregnancy diagnosed by ultrasonography who were admitted to Jinan Maternity and Child Care Hospital from January 2012 to May 2012 were enrolled in this study. To the observation group were assigned 35 patients whose ectopic pregnancy was due to salpingitis. The remaining 45 patients whose ectopic pregnancy was due to reasons other than endometriosis were assigned to the control group. Moreover, 32 healthy pregnant women were enrolled in this study at the same time as the healthy control group. Compared with the healthy control group, hsa-mir-1247 and hsa-mir-1269a were downregulated and upregulated, respectively, in patients with ectopic pregnancy (p<0.05). The difference was even more marked in patients with ectopic pregnancy due to salpingitis (p<0.05). The expression levels of hsa-mir-1247 and hsa‑mir-1269a were negatively correlated, and the correlation coefficient r and p-value was -0.667 and 0.006, respectively. Abnormal expression of hsa-mir-1247 and hsa-mir-1269a may be risk factors for ectopic pregnancy. Abnormal expression of hsa-mir-1247 and hsa-mir-1269a found in patients with ectopic pregnancy due to salpingitis may be used as biomarkers of ectopic pregnancy.
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1 

Fuchs N, Manoucheri E, Verbaan M and Einarsson JI: Laparoscopic management of extrauterine pregnancy in caesarean section scar: Description of a surgical technique and review of the literature. BJOG. 122:137–140. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Taran FA, Kagan KO, Hübner M, Hoopmann M, Wallwiener D and Brucker S: The diagnosis and treatment of ectopic pregnancy. Dtsch Arztebl Int. 112:693–703; quiz 704–705. 2015.PubMed/NCBI

3 

Köroğlu M, Kayhan A, Soylu FN, Erol B, Schmid-Tannwald C, Gürses C, Karademir İ, Ernst R, Yousuf A and Oto A: MR imaging of ectopic pregnancy with an emphasis on unusual implantation sites. Jpn J Radiol. 31:75–80. 2013. View Article : Google Scholar : PubMed/NCBI

4 

Mustafa KB, Hamid HA, Lim PS, Razi ZR and Omar MH: Heterotopic triplet pregnancy with bilateral tubal ectopic post-IVF-ICSI of two 12-cell embryos. Taiwan J Obstet Gynecol. 55:142–144. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Brouard KJ, Howard BR and Dyer RA: Hepatic pregnancy suspected at term and successful delivery of a live neonate with placental attachment to the right lobe of the liver. Obstet Gynecol. 126:207–210. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Abraham C and Seethappan V: Spontaneous live recurrent ectopic pregnancy after ipsilateral partial salpingectomy leading to tubal rupture. Int J Surg Case Rep. 7C:75–78. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Dabiri T, Marroquin GA, Bendek B, Agamasu E and Mikhail M: Advanced extrauterine pregnancy at 33 weeks with a healthy newborn. BioMed Res Int. 2014:1024792014. View Article : Google Scholar : PubMed/NCBI

8 

Agarwal V, Bell GW, Nam JW and Bartel DP: Predicting effective microRNA target sites in mammalian mRNAs. eLife. 4:e050052015. View Article : Google Scholar

9 

Wang J, Raimondo M, Guha S, Chen J, Diao L, Dong X, Wallace MB, Killary AM, Frazier ML, Woodward TA, et al: Circulating microRNAs in pancreatic iuice as candidate biomarkers of pancreatic cancer. J Cancer. 5:696–705. 2014. View Article : Google Scholar : PubMed/NCBI

10 

Carreras-Badosa G, Bonmatí A, Ortega FJ, Mercader JM, Guindo-Martínez M, Torrents D, Prats-Puig A, Martinez-Calcerrada JM, de Zegher F, Ibáñez L, et al: Dysregulation of placental miRNA in maternal obesity is associated with pre- and post-natal growth. J Clin Endocrinol Metab. 102:2584–2594. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Lu Y, Chen W, Jin L and Liu X: Sigmoid carcinoma by high-level serum β-human chorionic gonadotropin and ectopic pregnancy-like symptoms. Taiwan J Obstet Gynecol. 54:86–88. 2015. View Article : Google Scholar : PubMed/NCBI

12 

Grassetto A, Fullin G, Cerri G, Simioni P, Spiezia L and Maggiolo C: Management of severe bleeding in a ruptured extrauterine pregnancy: A theragnostic approach. Blood Coagul Fibrinolysis. 25:176–179. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Li Y, Yang Y, He QZ, Li SX and Lu HJ: Frozen section of uterine curetting in excluding the possibility of ectopic pregnancy - a clinicopathologic study of 715 cases. Clin Exp Obstet Gynecol. 41:419–422. 2014.PubMed/NCBI

14 

Hudeček R, Felsingerová Z, Felsinger M and Jandakova E: Laparoscopic treatment of cesarean scar ectopic pregnancy. J Gynecol Surg. 30:309–311. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Goyaux N, Leke R, Keita N and Thonneau P: Ectopic pregnancy in African developing countries. Acta Obstet Gynecol Scand. 82:305–312. 2003. View Article : Google Scholar : PubMed/NCBI

16 

Marinova M, Rauch M, Schild HH and Strunk HM: Novel non-invasive treatment with high-intensity focused ultrasound (HIFU). Ultraschall Med. 37:46–55. 2016.PubMed/NCBI

17 

Wierichs RJ and Meyer-Lueckel H: Systematic review on noninvasive treatment of root caries lesions. J Dent Res. 94:261–271. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Dominguez F, Moreno-Moya JM, Lozoya T, Romero A, Martínez S, Monterde M, Gurrea M, Ferri B, Núñez MJ, Simón C, et al: Embryonic miRNA profiles of normal and ectopic pregnancies. PLoS One. 9:e1021852014. View Article : Google Scholar : PubMed/NCBI

19 

Ohannessian A, Crochet P, Courbiere B, Gnisci A and Agostini A: Methotrexate treatment for ectopic pregnancy after assisted reproductive technology: A case-control study. Gynecol Obstet Fertil. 44:341–344. 2016. View Article : Google Scholar : PubMed/NCBI

20 

Alkatout I, Honemeyer U, Strauss A, Tinelli A, Malvasi A, Jonat W, Mettler L and Schollmeyer T: Clinical diagnosis and treatment of ectopic pregnancy. Obstet Gynecol Surv. 68:571–581. 2013. View Article : Google Scholar : PubMed/NCBI

21 

Perkins KM, Boulet SL, Kissin DM and Jamieson DJ: Risk of ectopic pregnancy associated with assisted reproductive technology in the United States, 2001–2011. Obstet Gynecol. 102:e38–e39. 2014.

22 

Weiss A, Beck-Fruchter R, Golan J, Lavee M, Geslevich Y and Shalev E: Ectopic pregnancy risk factors for ART patients undergoing the GnRH antagonist protocol: A retrospective study. Reprod Biol Endocrinol. 14:122016. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang S, Sun Q, Jiang X and Gao F: Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. Exp Ther Med 15: 4901-4905, 2018.
APA
Zhang, S., Sun, Q., Jiang, X., & Gao, F. (2018). Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. Experimental and Therapeutic Medicine, 15, 4901-4905. https://doi.org/10.3892/etm.2018.5998
MLA
Zhang, S., Sun, Q., Jiang, X., Gao, F."Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis". Experimental and Therapeutic Medicine 15.6 (2018): 4901-4905.
Chicago
Zhang, S., Sun, Q., Jiang, X., Gao, F."Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis". Experimental and Therapeutic Medicine 15, no. 6 (2018): 4901-4905. https://doi.org/10.3892/etm.2018.5998
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang S, Sun Q, Jiang X and Gao F: Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. Exp Ther Med 15: 4901-4905, 2018.
APA
Zhang, S., Sun, Q., Jiang, X., & Gao, F. (2018). Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. Experimental and Therapeutic Medicine, 15, 4901-4905. https://doi.org/10.3892/etm.2018.5998
MLA
Zhang, S., Sun, Q., Jiang, X., Gao, F."Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis". Experimental and Therapeutic Medicine 15.6 (2018): 4901-4905.
Chicago
Zhang, S., Sun, Q., Jiang, X., Gao, F."Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis". Experimental and Therapeutic Medicine 15, no. 6 (2018): 4901-4905. https://doi.org/10.3892/etm.2018.5998
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