Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
June-2018 Volume 15 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
June-2018 Volume 15 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule

  • Authors:
    • Xiaoming Wang
    • Liang Lv
    • Qinyun Zheng
    • Xianlong Huang
    • Biqiang Li
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, The General Chongqing Hospital, Chongqing 400014, P.R. China, Department of Physical Examination Center, The General Chongqing Hospital, Chongqing 400014, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 4703-4708
    |
    Published online on: April 10, 2018
       https://doi.org/10.3892/etm.2018.6041
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study aimed to evaluate the diagnostic value of 64‑slice spiral multivariate computed tomography (CT) combined with dynamic contrast‑enhanced scanning for benign and malignant solitary pulmonary nodules (SPNs). A total of 93 patients with SPN as diagnosed by CT were included. All these patients were subjected to routine and dynamic enhancement CT scanning. After reconstruction, the morphological characteristics following dynamic enhancement were analyzed, and compared for the benign and malignant SPN cases. The incidences of lobulation, spicular sign, pleural indentation and vacuole sign in the malignant SPN group were significantly higher compared with the benign SPN group. During the dynamic enhancement scanning, the CT values at all the time points for the inflammatory and malignant SPN groups were significantly higher than the benign SPN group. No significant differences were observed in the dynamic enhancement CT values at 30, 60, 90 and 120 sec between the inflammatory, and malignant SPN groups. However, in the inflammatory SPN group, the dynamic enhancement CT values at 300 and 540 sec were significantly lower than the malignant SPN group. Notably, the diagnostic accordance rate for the morphological signs combined with dynamic enhancement diagnosis was significantly higher than the morphological signs alone. The 64‑slice spiral CT morphological signs combined with dynamic enhancement detection can be more effective for the differential diagnosis of benign and malignant SPN, which may provide potent evidence for the early clinical treatment.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Wahidi MM, Govert JA, Goudar RK, Gould MK and McCrory DC: American College of Chest Physicians: Evidence for the treatment of patients with pulmonary nodules: When is it lung cancer? ACCP evidence-based clinical practice guidelines (2nd edition). Chest. 132 3 Suppl:94S–107S. 2007. View Article : Google Scholar : PubMed/NCBI

2 

Prakashini K, Babu S, Rajgopal KV and Kokila KR: Role of computer Aided diagnosis (CAD) in the detection of pulmonary nodules on 64 row multi detector computed tomography. Lung India. 33:391–397. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Lin JZ, Zhang L, Zhang CY, Yang L, Lou HN and Wang ZG: Application of gemstone spectral computed tomography imaging in the characterization of solitary pulmonary nodules: Preliminary result. J Comput Assist Tomogr. 40:907–911. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Truong MT, Sabloff BS and Ko JP: Multidetector CT of solitary pulmonary nodules. Radiol Clin North Am. 48:141–155. 2010. View Article : Google Scholar : PubMed/NCBI

5 

Wu B: Comparison and analysis of diagnosis spiral CT and high-resolution CT for peripheral lung cancer with diameter of <3 cm. Chin Med Herald. 8:78–79. 2011.(In Chinese).

6 

Wang B and Li H: Significance of dynamic contrast-enhanced CT in the differential diagnosis of solitary pulmonary nodules. Chin J Lab Diagn. 16:1495–1496. 2012.(In Chinese).

7 

LN E and Ma D: Imaging diagnosis and management of small pulmonary nodules. Chin J Radio. 43:332–334. 2009.(In Chinese).

8 

Shi Z, Wang Y and He X: Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography. Exp Ther Med. 12:1750–1754. 2016. View Article : Google Scholar : PubMed/NCBI

9 

He Q, Yu F, Dai P, Liu Z, Guo R and Yang B: Comparative study of MSCT and pathological findings of solitary pulmonary nodules. Chongqing Med. 43:3912–3915. 2014.

10 

Yang D, Li Y, Liu J, Jiang G, Li J, Zhao H, Yang F, Liu Y, Zhou Z, Bu L and Wang J: Study on solitary pulmonary nodules: Correlation between diameter and clinical manifestation and pathological features. Zhongguo Fei Ai Za Zhi. 13:607–611. 2010.(In Chinese). PubMed/NCBI

11 

Macdonald K, Searle J and Lyburn I: The role of dual time point FDG PET imaging in the evaluation of solitary pulmonary nodules with an initial standard uptake value less than 2.5. Clin Radiol. 66:244–250. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Harders SW, Madsen HH, Rasmussen TR, Hager H and Rasmussen F: High resolution spiral CT for determining the malignant potential of solitary pulmonary nodules: Refining and testing the test. Acta Radiol. 52:401–409. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Li Y, Sui X and Yang D: Solitary pulmonary nodules: A risk factor analysis. Chin J Thoracic Cardiovasc Surg. 26:161–164. 2010.(In Chinese).

14 

Cui Y, Ma D and Yang J: The value of pleural indentation in the diagnosis of pulmonary nodule: A meta-analysis. J Cap Med Univ. 28:709–712. 2007.

15 

Ma YH, Li YX and Fang Y: A comparative study on pathology and CT signs of small peripheral lung cancer. Chin J Mod Med. 100–103. 2013.(In Chinese).

16 

Zhao BY, Geng C and Beng BZ: The value of CT-vessel convergence sign in differential diagnosis of SPN. Chin Imaging Integr Trad West Med. 4:339–341. 2006.(In Chinese).

17 

Khan A: ACR Appropriateness criteria on solitary pulmonary nodule. J Am Coll Radiol. 4:152–155. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Lin HL: Development in the diagnosis of solitary pulmonary nodule by CT. Med Recapitulate (Issue 11). 1725–1727. 2010.(In Chinese).

19 

Li Y, Chen KZ, Sui XZ, Bu L, Zhou ZL, Yang F, Liu YG, Zhao H, Li JF, Liu J, et al: Establishment of a mathematical prediction model to evaluate the probability of malignancy or benign in patients with solitary pulmonary nodules. Beijing Da Xue Xue Bao Yi Xue Ban. 43:450–454. 2011.(In Chinese). PubMed/NCBI

20 

Kim JH, Kim HJ, Lee KH, Kim KH and Lee HL: Solitary pulmonary nodules: A comparative study evaluated with contrast-enhanced dynamic MR imaging and CT. J Comput Assist Tomogr. 28:766–775. 2004. View Article : Google Scholar : PubMed/NCBI

21 

Swensen SJ, Viggiano RW, Midthun DE, Müller NL, Sherrick A, Yamashita K, Naidich DP, Patz EF, Hartman TE, Muhm JR and Weaver AL: Lung nodule enhancement at CT: Multicenter study. Radiology. 214:73–80. 2000. View Article : Google Scholar : PubMed/NCBI

22 

Zhang M, Hua Z and Yu Z: Quantitative investigation of solitary pulmonary nodules with dynamic contrast-enhanced functional CT. Clin Oncol Cancer Res. 1:229–235. 2004.

23 

Jeong YJ, Lee KS, Jeong SY, Chung MJ, Shim SS, Kim H, Kwon OJ and Kim S: Solitary pulmonary nodule: Characterization with combined wash-in and washout features at dynamic multi-detector row CT. Radiology. 237:675–683. 2005. View Article : Google Scholar : PubMed/NCBI

24 

Zhang M and Kono M: Solitary pulmonary nodules: Evaluation of blood flow patterns with dynamic CT. Radiology. 205:471–478. 1997. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Wang X, Lv L, Zheng Q, Huang X and Li B: Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule. Exp Ther Med 15: 4703-4708, 2018.
APA
Wang, X., Lv, L., Zheng, Q., Huang, X., & Li, B. (2018). Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule. Experimental and Therapeutic Medicine, 15, 4703-4708. https://doi.org/10.3892/etm.2018.6041
MLA
Wang, X., Lv, L., Zheng, Q., Huang, X., Li, B."Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule". Experimental and Therapeutic Medicine 15.6 (2018): 4703-4708.
Chicago
Wang, X., Lv, L., Zheng, Q., Huang, X., Li, B."Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule". Experimental and Therapeutic Medicine 15, no. 6 (2018): 4703-4708. https://doi.org/10.3892/etm.2018.6041
Copy and paste a formatted citation
x
Spandidos Publications style
Wang X, Lv L, Zheng Q, Huang X and Li B: Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule. Exp Ther Med 15: 4703-4708, 2018.
APA
Wang, X., Lv, L., Zheng, Q., Huang, X., & Li, B. (2018). Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule. Experimental and Therapeutic Medicine, 15, 4703-4708. https://doi.org/10.3892/etm.2018.6041
MLA
Wang, X., Lv, L., Zheng, Q., Huang, X., Li, B."Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule". Experimental and Therapeutic Medicine 15.6 (2018): 4703-4708.
Chicago
Wang, X., Lv, L., Zheng, Q., Huang, X., Li, B."Differential diagnostic value of 64‑slice spiral computed tomography in solitary pulmonary nodule". Experimental and Therapeutic Medicine 15, no. 6 (2018): 4703-4708. https://doi.org/10.3892/etm.2018.6041
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team