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Article

[18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis

  • Authors:
    • Lu Sun
    • Yuanfei Dong
    • Na Zhang
    • Xing Lv
    • Qiusong Chen
    • Wei Wei
  • View Affiliations / Copyright

    Affiliations: Department of Rheumatology and Immunology, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China, Department of PET‑CT Diagnostics, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China
  • Pages: 5023-5028
    |
    Published online on: April 13, 2018
       https://doi.org/10.3892/etm.2018.6066
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Abstract

[18F]fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG‑PET/CT) is useful for diagnosing cancers and inflammatory diseases. A polymyositis/dermatomyositis (PM/DM) lesion is an inflammatory heterogeneous disease of the striated muscle. In the present study, the maximum standardized uptake value (SUVmax) was compared between 22 cases with definite or probable PM/DM (PM/DM group) that underwent [18F]FDG‑PET/CT examination and the same number of patients with no myopathy. The average proximal muscle FDG uptake value (SUVaverage) for each patient was represented by calculating the average of the SUVmax for these muscles bilaterally. The correlation between creatine kinase (CK), serum creatine kinase isoenzyme, myodynamia of the proximal limb girdle muscle and SUVmax of each muscle group were analyzed. The results indicated that the SUVmax was markedly different between the PM/DM group and the non‑myopathy group. It was demonstrated that [18F]FDG‑PET/CT has a diagnostic value for PM/DM. The serum CK levels and the SUVaverage were negatively correlated with myodynamia. [18F]FDG‑PET/CT may be used for examination to assess the severity of myositis. Furthermore, it may provide detection sites for muscle biopsy in patients with myositis.
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Copy and paste a formatted citation
Spandidos Publications style
Sun L, Dong Y, Zhang N, Lv X, Chen Q and Wei W: [18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis. Exp Ther Med 15: 5023-5028, 2018.
APA
Sun, L., Dong, Y., Zhang, N., Lv, X., Chen, Q., & Wei, W. (2018). [18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis. Experimental and Therapeutic Medicine, 15, 5023-5028. https://doi.org/10.3892/etm.2018.6066
MLA
Sun, L., Dong, Y., Zhang, N., Lv, X., Chen, Q., Wei, W."[18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis". Experimental and Therapeutic Medicine 15.6 (2018): 5023-5028.
Chicago
Sun, L., Dong, Y., Zhang, N., Lv, X., Chen, Q., Wei, W."[18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis". Experimental and Therapeutic Medicine 15, no. 6 (2018): 5023-5028. https://doi.org/10.3892/etm.2018.6066
Copy and paste a formatted citation
x
Spandidos Publications style
Sun L, Dong Y, Zhang N, Lv X, Chen Q and Wei W: [18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis. Exp Ther Med 15: 5023-5028, 2018.
APA
Sun, L., Dong, Y., Zhang, N., Lv, X., Chen, Q., & Wei, W. (2018). [18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis. Experimental and Therapeutic Medicine, 15, 5023-5028. https://doi.org/10.3892/etm.2018.6066
MLA
Sun, L., Dong, Y., Zhang, N., Lv, X., Chen, Q., Wei, W."[18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis". Experimental and Therapeutic Medicine 15.6 (2018): 5023-5028.
Chicago
Sun, L., Dong, Y., Zhang, N., Lv, X., Chen, Q., Wei, W."[18F]Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis". Experimental and Therapeutic Medicine 15, no. 6 (2018): 5023-5028. https://doi.org/10.3892/etm.2018.6066
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