Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
June-2018 Volume 15 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
June-2018 Volume 15 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors

  • Authors:
    • Jidong Zhang
    • Yu Song
    • Yang Ji
    • Yiying Song
    • Shanglang Cai
    • Yanling Yu
    • Song Liu
    • Wenzhong Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, The Affiliated Hospital of Medical College Qingdao University, Qingdao, Shandong 266001, P.R. China, Department of Orthodontics, Qingdao Stomatological Hospital, Qingdao, Shandong 266001, P.R. China, Department of Invasive Technology, The Affiliated Hospital of Medical College Qingdao University, Qingdao, Shandong 266001, P.R. China
  • Pages: 4771-4776
    |
    Published online on: April 13, 2018
       https://doi.org/10.3892/etm.2018.6070
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The correlation between coronary artery disease (CAD) and obstructive sleep apnea syndrome (OSAS) was investigated to analyze its risk factors. A total of 84 patients with suspected CAD due to chest tightness and pain or nocturnal angina, were selected. They were admitted and received coronary angiography in The Affiliated Hospital of Medical College Qingdao University from March, 2016 to June, 2017. The vital signs were monitored, and the sleep monitoring was performed before and after coronary angiography. Before angiography, the fasting blood was drawn for blood biochemical detection, followed by routine electrocardiogram and echocardiographic examination. In addition, the body mass index was calculated and whether patients suffered from hypertension and diabetes mellitus was observed. The patients were divided into the control group (patients with a negative coronary angiography) and the CAD group (patients with a positive coronary angiography). There were 34 cases in the control group, including 21 cases of OSAS (61.76%), and 50 in the CAD group, including 40 cases of OSAS (80.00%). Statistical analysis revealed that there were statistically significant differences in the apnea hypopnea index (AHI), lowest oxygen saturation, degree of coronary stenosis (Gensini score) and triglyceride level between the two groups (P<0.05). There were no statistically significant differences in the cholesterol level and prevalence rates of hypertension and diabetes mellitus between the two groups. Logistic regression analysis revealed that smoking and AHI >20 were the risk factors of CAD (OR=7.036 and 5.377). Thus, CAD is closely correlated with OSAS and AHI >20 is one of the risk factors of CAD.
View Figures

Figure 1

View References

1 

Imataka G, Nakajima I, Goto K, Konno W, Hirabayashi H and Arisaka O: Drop episodes improved after tracheotomy: A case of Coffin-Lowry syndrome associated with obstructive sleep apnea syndrome. Eur Rev Med Pharmacol Sci. 20:498–501. 2016.PubMed/NCBI

2 

Lombardi C, Tobaldini E, Montano N, Losurdo A and Parati G: Obstructive sleep apnea syndrome (OSAS) and cardiovascular system. Med Lav. 108:276–282. 2017.PubMed/NCBI

3 

Barbosa FR, Silva CM, Lima GA, Warszawski L, Domingues RC, Dominic M, Fontes R, Neto Vieira L and Gadelha MR: Prevalence of obstructive sleep apnea in patients with prolactinoma before and after treatment with dopamine agonists. Pituitary. 17:441–449. 2014. View Article : Google Scholar : PubMed/NCBI

4 

Buccheri A, Chinè F, Fratto G and Manzon L: Rapid maxillary expansion in obstructive sleep apnea in young patients: Cardio-Respiratory monitoring. J Clin Pediatr Dent. 41:312–316. 2017. View Article : Google Scholar : PubMed/NCBI

5 

Karimzadeh F, Nami M and Boostani R: Sleep microstructure dynamics and neurocognitive performance in obstructive sleep apnea syndrome patients. J Integr Neurosci. 16:127–142. 2017. View Article : Google Scholar : PubMed/NCBI

6 

Alvarez-Sabín J, Romero O, Delgado P, Quintana M, Santamarina E, Ferré A, Maisterra O, Riba-Llena I, Montaner J and Sampol G: Obstructive sleep apnea and silent cerebral infarction in hypertensive individuals. J Sleep Res. 20:962–1105. 2017.

7 

Li L, Lu J, Xue W, Wang L, Zhai Y, Fan Z, Wu G, Fan F, Li J, Zhang C, et al: Target of obstructive sleep apnea syndrome merge lung cancer: Based on big data platform. Oncotarget. 8:21567–21578. 2017.PubMed/NCBI

8 

Micarelli A, Liguori C, Viziano A, Izzi F, Placidi F and Alessandrini M: Integrating postural and vestibular dimensions to depict impairment in moderate-to-severe obstructive sleep apnea syndrome patients. J Sleep Res. 26:487–494. 2017. View Article : Google Scholar : PubMed/NCBI

9 

Arik B, Inci MF, Gumus C, Varol K, Ege MR, Dogan OT and Zorlu A: Advanced age and apnea-hypopnea index predict subclinical atherosclerosis in patients with obstructive sleep apnea syndrome. Multidiscip Respir Med. 8:92013. View Article : Google Scholar : PubMed/NCBI

10 

Meng S, Fang L, Wang CQ, Wang LS, Chen MT and Huang XH: Impact of obstructive sleep apnoea on clinical characteristics and outcomes in patients with acute coronary syndrome following percutaneous coronary intervention. J Int Med Res. 37:1343–1353. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Zhu H, Xu H, Chen R, Liu S, Xia Y, Fu Y, Li X, Qian Y, Zou J, Yi H, et al: Smoking, obstructive sleep apnea syndrome and their combined effects on metabolic parameters: Evidence from a large cross-sectional study. Sci Rep. 7:88512017. View Article : Google Scholar : PubMed/NCBI

12 

Capodanno D, Milazzo G, Cumbo M, Marchese A, Salemi A, Quartarone L, Benvenuto E, Galseran C, Distefano SM and Tamburino C: Positive airway pressure in patients with coronary artery disease and obstructive sleep apnea syndrome. J Cardiovasc Med (Hagerstown). 15:402–406. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Singh A, Prasad R, Garg R, Kant S, Hosmane GB, Dubey A, Agarwal A and Verma RK: A study to estimate prevalence and risk factors of obstructive sleep apnoea syndrome in a semi-urban Indian population. Monaldi Arch Chest Dis. 87:7732017. View Article : Google Scholar : PubMed/NCBI

14 

Mihaicuta S, Udrescu M, Topirceanu A and Udrescu L: Network science meets respiratory medicine for OSAS phenotyping and severity prediction. PeerJ. 5:e32892017. View Article : Google Scholar : PubMed/NCBI

15 

Wang ZH, Zhu D, Xie S, Deng Y, Pan Y, Ren J and Liu HG: Inhibition of rho-kinase attenuates left ventricular remodeling caused by chronic intermittent hypoxia in rats via suppressing myocardial inflammation and apoptosis. J Cardiovasc Pharmacol. 70:102–109. 2017. View Article : Google Scholar : PubMed/NCBI

16 

Vitulano N, Di Marco Berardino A, Re A, Riccioni G, Perna F, Mormile F, Valente S and Bellocci F: Obstructive sleep apnea and heart disease: The biomarkers point of view. Front Biosci (Schol Ed). 5:588–599. 2013. View Article : Google Scholar : PubMed/NCBI

17 

Foody J, Huo Y, Ji L, Zhao D, Boyd D, Meng HJ, Shiff S and Hu D: Unique and varied contributions of traditional CVD risk factors: A systematic literature review of CAD risk factors in China. Clin Med Insights Cardiol. 7:59–86. 2013. View Article : Google Scholar : PubMed/NCBI

18 

Schmermund A, Lehmann N, Bielak LF, Yu P, Sheedy PF II, Cassidy-Bushrow AE, Turner ST, Moebus S, Möhlenkamp S, Stang A, et al: Comparison of subclinical coronary atherosclerosis and risk factors in unselected populations in Germany and USA. Atherosclerosis. 195:e207–e216. 2007. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang J, Song Y, Ji Y, Song Y, Cai S, Yu Y, Liu S and Zhang W: Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors. Exp Ther Med 15: 4771-4776, 2018.
APA
Zhang, J., Song, Y., Ji, Y., Song, Y., Cai, S., Yu, Y. ... Zhang, W. (2018). Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors. Experimental and Therapeutic Medicine, 15, 4771-4776. https://doi.org/10.3892/etm.2018.6070
MLA
Zhang, J., Song, Y., Ji, Y., Song, Y., Cai, S., Yu, Y., Liu, S., Zhang, W."Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors". Experimental and Therapeutic Medicine 15.6 (2018): 4771-4776.
Chicago
Zhang, J., Song, Y., Ji, Y., Song, Y., Cai, S., Yu, Y., Liu, S., Zhang, W."Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors". Experimental and Therapeutic Medicine 15, no. 6 (2018): 4771-4776. https://doi.org/10.3892/etm.2018.6070
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang J, Song Y, Ji Y, Song Y, Cai S, Yu Y, Liu S and Zhang W: Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors. Exp Ther Med 15: 4771-4776, 2018.
APA
Zhang, J., Song, Y., Ji, Y., Song, Y., Cai, S., Yu, Y. ... Zhang, W. (2018). Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors. Experimental and Therapeutic Medicine, 15, 4771-4776. https://doi.org/10.3892/etm.2018.6070
MLA
Zhang, J., Song, Y., Ji, Y., Song, Y., Cai, S., Yu, Y., Liu, S., Zhang, W."Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors". Experimental and Therapeutic Medicine 15.6 (2018): 4771-4776.
Chicago
Zhang, J., Song, Y., Ji, Y., Song, Y., Cai, S., Yu, Y., Liu, S., Zhang, W."Correlation between coronary artery disease and obstructive sleep apnea syndrome and analysis of risk factors". Experimental and Therapeutic Medicine 15, no. 6 (2018): 4771-4776. https://doi.org/10.3892/etm.2018.6070
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team