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Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis

  • Authors:
    • Rong Fu
    • Xu Song
    • Dexing Su
    • Shunrong Li
    • Lizhen Gao
    • Chunmei Ji
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, People's Hospital of Rizhao, Rizhao, Shandong 276800, P.R. China, Department of Respiratory Medicine, People's Hospital of Rizhao, Rizhao, Shandong 276800, P.R. China, Department of Cardiology, People's Hospital of Zhangqiu, Jinan, Shandong 250200, P.R. China, Department of Critical Care Medicine, People's Hospital of Zhangqiu, Jinan, Shandong 250200, P.R. China, Department of Clinical Laboratory, People's Hospital of Zhangqiu, Jinan, Shandong 250200, P.R. China, Department of Clinical Laboratory, People's Hospital of Weifang, Weifang, Shandong 261000, P.R. China
  • Pages: 241-245
    |
    Published online on: May 7, 2018
       https://doi.org/10.3892/etm.2018.6137
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Abstract

The serum triggering receptor expressed on myeloid cell (TREM)-like transcription factor-1 [soluble TREM-like transcript-1 (STLT-1)] and bilirubin levels were investigated in patients with acute coronary syndrome and the correlation with prognosis. A total of 125 patients of acute coronary syndrome admitted to the Department of Cardiology in People's Hospital of Rizhao were selected, including 45 cases with ST-segment elevation myocardial infarction (STEMI), 36 cases with non-ST-elevation myocardial infarction (NSTEMI) and 44 cases with unstable angina pectoris (UAP), while 48 subjects were enrolled as the normal control. The serum STLT-1 and bilirubin levels on admission and on the 3rd, 7th and 10th day after admission of patients in each group were respectively determined, the level changes of these two indicators in serum during the initial stage of acute coronary syndrome were analyzed, and their effects on prognosis of patients were analyzed. STLT-1 levels in groups STEMI, NSTEMI and UAP were higher than those in the normal control group, and serum levels of STLT-1 in groups STEMI and NSTEMI were higher than those in group UAP. Bilirubin levels in groups STEMI, NSTEMI and UAP were lower than those in the normal control group, and serum levels of bilirubin in groups STEMI and NSTEMI were lower than those in group UAP. The proportions of complications in patients of groups STEMI and NSTEMI were significantly higher than those in group UAP (P<0.05). The results showed that the timely and effective treatment administered to patients with acute coronary syndrome during the initial stage to reduce the level of STLT-1 in serum and enhance bilirubin to a relatively high level is conducive in ameliorating the prognosis of patients, which is of clinical significance.
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Copy and paste a formatted citation
Spandidos Publications style
Fu R, Song X, Su D, Li S, Gao L and Ji C: Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis. Exp Ther Med 16: 241-245, 2018.
APA
Fu, R., Song, X., Su, D., Li, S., Gao, L., & Ji, C. (2018). Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis. Experimental and Therapeutic Medicine, 16, 241-245. https://doi.org/10.3892/etm.2018.6137
MLA
Fu, R., Song, X., Su, D., Li, S., Gao, L., Ji, C."Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis". Experimental and Therapeutic Medicine 16.1 (2018): 241-245.
Chicago
Fu, R., Song, X., Su, D., Li, S., Gao, L., Ji, C."Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis". Experimental and Therapeutic Medicine 16, no. 1 (2018): 241-245. https://doi.org/10.3892/etm.2018.6137
Copy and paste a formatted citation
x
Spandidos Publications style
Fu R, Song X, Su D, Li S, Gao L and Ji C: Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis. Exp Ther Med 16: 241-245, 2018.
APA
Fu, R., Song, X., Su, D., Li, S., Gao, L., & Ji, C. (2018). Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis. Experimental and Therapeutic Medicine, 16, 241-245. https://doi.org/10.3892/etm.2018.6137
MLA
Fu, R., Song, X., Su, D., Li, S., Gao, L., Ji, C."Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis". Experimental and Therapeutic Medicine 16.1 (2018): 241-245.
Chicago
Fu, R., Song, X., Su, D., Li, S., Gao, L., Ji, C."Serum STLT-1 and bilirubin levels in patients with acute coronary syndrome and correlation with prognosis". Experimental and Therapeutic Medicine 16, no. 1 (2018): 241-245. https://doi.org/10.3892/etm.2018.6137
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