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July-2018 Volume 16 Issue 1

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Case Report

Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report

  • Authors:
    • Sujuan Feng
    • Yuan Zhuang
    • Hang Liu
    • Xiaodong Zhang
  • View Affiliations / Copyright

    Affiliations: Institute of Uro‑Nephrology, Beijing Chao‑Yang Hospital, Capital Medical University, Beijing 100020, P.R. China, Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, P.R. China
  • Pages: 360-363
    |
    Published online on: May 17, 2018
       https://doi.org/10.3892/etm.2018.6176
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Abstract

Operational tolerance of an allograft kidney is the optimal condition in patients following kidney transplantation and recipient‑mediated immunological rejection still remains the primary challenge following transplantation. In the present study, a case of long‑term survival is reported in a patient following kidney transplantation without maintenance immunosuppression therapies for >10 years. Although the pathological conditions of the transplanted kidney revealed a degree of impaired kidney function, the patient exhibited a serum creatinine level of 119.2 µmol/l and no significant changes were observed in T or B cell biomarkers associated with immunologic tolerance. Notably, the patient's allograft was functioning normally. Consequently, further studies may need to elucidate the development of operational tolerance.
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Copy and paste a formatted citation
Spandidos Publications style
Feng S, Zhuang Y, Liu and Zhang X: Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report. Exp Ther Med 16: 360-363, 2018.
APA
Feng, S., Zhuang, Y., Liu, ., & Zhang, X. (2018). Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report. Experimental and Therapeutic Medicine, 16, 360-363. https://doi.org/10.3892/etm.2018.6176
MLA
Feng, S., Zhuang, Y., Liu, ., Zhang, X."Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report". Experimental and Therapeutic Medicine 16.1 (2018): 360-363.
Chicago
Feng, S., Zhuang, Y., Liu, ., Zhang, X."Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report". Experimental and Therapeutic Medicine 16, no. 1 (2018): 360-363. https://doi.org/10.3892/etm.2018.6176
Copy and paste a formatted citation
x
Spandidos Publications style
Feng S, Zhuang Y, Liu and Zhang X: Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report. Exp Ther Med 16: 360-363, 2018.
APA
Feng, S., Zhuang, Y., Liu, ., & Zhang, X. (2018). Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report. Experimental and Therapeutic Medicine, 16, 360-363. https://doi.org/10.3892/etm.2018.6176
MLA
Feng, S., Zhuang, Y., Liu, ., Zhang, X."Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report". Experimental and Therapeutic Medicine 16.1 (2018): 360-363.
Chicago
Feng, S., Zhuang, Y., Liu, ., Zhang, X."Long‑term survival in a recipient of kidney transplant without maintenance immunosuppression: A case report". Experimental and Therapeutic Medicine 16, no. 1 (2018): 360-363. https://doi.org/10.3892/etm.2018.6176
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