Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
November-2018 Volume 16 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2018 Volume 16 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Role of miR‑520b in non‑small cell lung cancer

  • Authors:
    • Linlin Zhang
    • Shuangquan Yu
  • View Affiliations / Copyright

    Affiliations: Respiratory Department, Shandong Chest Hospital, Jinan No. 5 People's Hospital, Jinan, Shandong 250000, P.R. China, Department of General Surgery, Jinan No. 5 People's Hospital, Jinan, Shandong 250000, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3987-3995
    |
    Published online on: September 12, 2018
       https://doi.org/10.3892/etm.2018.6732
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to investigate the expression of microRNA (miR)‑520b in non‑small cell lung cancer (NSCLC) and its biological functions. Reverse transcription‑quantitative polymerase chain reaction was used to detect the expression of miR‑520b in 52 cases of NSCLC tissues, and its associations with tumor clinical staging and lymph node metastasis were analyzed. miR‑520b mimics was transfected into A549 and Calu‑3 cells. Cell proliferation, cell cycle, and cell invasion and migration abilities were assessed via cell counting kit‑8 assay, flow cytometry and Transwell chamber assay, respectively. Western blot analysis was performed to detected protein expression levels, and dual luciferase reporter assay was used to detect the gene interaction. miR‑520b expression was significantly downregulated in NSCLC. The expression of miR‑520b in tumor tissues at N1 stage was lower than that at the N0 stage. miR‑520b expression was negatively associated with clinical TNM staging. Furthermore, miR‑520b mimic transfection inhibited the proliferation and invasion and metastasis abilities of A549 and Calu‑3 cells. The expression of Rab22A was downregulated in the miR‑520b mimics‑transfected cells, whereas E‑cadherin expression was increased, and vimentin expression was downregulated. Dual luciferase reporter assay demonstrated that miR‑520b directly targeted the expression of Rab22A. Furthermore, Rab22A reversal downregulated the inhibitory effect of miR‑520b. miR‑520b expression was downregulated in NSCLC, which was negatively correlated with lymph node metastasis and TNM staging. miR‑520b targeted on Rab22A to work as a tumor suppressor, inhibiting tumor proliferation and metastasis.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Gu Y, Lv H, Zhao J, Li Q, Mu G, Li J, Wuyang J, Lou G, Wang R, Zhang Y and Huang X: Influence of the number and interval of treatment cycles on cytokine-induced killer cells and their adjuvant therapeutic effects in advanced non-small-cell lung cancer (NSCLC). Int Immunopharmacol. 50:263–269. 2017. View Article : Google Scholar : PubMed/NCBI

2 

Lamb YN and Scott LJ: Osimertinib: A review in T790M-positive advanced non-small cell lung cancer. Target Oncol. 12:555–562. 2017. View Article : Google Scholar : PubMed/NCBI

3 

Powell AC, Mirhadi AJ, Loy BA, Happe LE, Long JW, Kren EM and Gupta AK: Presentation at computed tomography (CT) scan of the thorax and first year diagnostic and treatment utilization among patients diagnosed with lung cancer. PLoS One. 12:e01813192017. View Article : Google Scholar : PubMed/NCBI

4 

He J, Yu L, Wang CM and Zhou XF: MiR-1275 promotes non-small cell lung cancer cell proliferation and metastasis by regulating LZTS3 expression. Eur Rev Med Pharmacol Sci. 22:2680–2687. 2018.PubMed/NCBI

5 

Chae YK, Arya A, Iams W, Cruz MR, Chandra S, Choi J and Giles F: Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC). J Immunother Cancer. 6:392018. View Article : Google Scholar : PubMed/NCBI

6 

Proto C, Russo Lo G, Corrao G, Ganzinelli M, Facchinetti F, Minari R, Tiseo M and Garassino MC: Treatment in EGFR-mutated non-small cell lung cancer: How to block the receptor and overcome resistance mechanisms. Tumori. 103:325–337. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Botsa EI, Thanou IL, Papatheodoropoulou AT and Thanos LI: Thermal ablation in the management of adrenal metastasis originating from Non-small cell lung cancer: A 5-year Single-center experience. Chin Med J (Engl). 130:2027–2032. 2017. View Article : Google Scholar : PubMed/NCBI

8 

Zhang G, Zhang D, Wu J, Zhang F, Zhu Z, Chen K, Zhang N, Jin J, Feng J, Lin N, et al: Low serum levels of Pre-surgical total cholesterol are associated with unfavorable overall survival in patients with operable Non-small cell lung cancer. Clin Lab. 64:321–327. 2018. View Article : Google Scholar : PubMed/NCBI

9 

Camidge DR, Kim DW, Tiseo M, Langer CJ, Ahn MJ, Shaw AT, Huber RM, Hochmair MJ, Lee DH, Bazhenova LA, et al: Exploratory analysis of brigatinib activity in patients with anaplastic lymphoma Kinase-positive Non-small-cell lung cancer and brain metastases in two clinical trials. J Clin Oncol: JCO2017775841. 2018. View Article : Google Scholar

10 

Xu Y, Zhang F, Pan X, Wang G, Zhu L, Zhang J, Wen D and Lu S: Xenograft tumors derived from malignant pleural effusion of the patients with non-small-cell lung cancer as models to explore drug resistance. Cancer Commun (Lond). 38:192018. View Article : Google Scholar : PubMed/NCBI

11 

Zhou J, Yu Y, Pei Y, Cao C, Ding C, Wang D, Sun L and Niu G: A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer. Oncotarget. 8:65469–65480. 2017.PubMed/NCBI

12 

Ali A, Kim SH, Kim MJ, Choi MY, Kang SS, Cho GJ, Kim YS, Choi JY and Choi WS: O-GlcNAcylation of NF-κB promotes lung metastasis of cervical cancer cells via upregulation of CXCR4 expression. Mol Cells. 40:476–484. 2017.PubMed/NCBI

13 

Casaluce F, Sgambato A, Maione P, Sacco PC, Santabarbara G and Gridelli C: Selumetinib for the treatment of non-small cell lung cancer. Expert Opin Investig Drugs. 26:973–984. 2017. View Article : Google Scholar : PubMed/NCBI

14 

Shlomi D, Abud M, Liran O, Bar J, Gai-Mor N, Ilouze M, Onn A, Ben-Nun A, Haick H and Peled N: Detection of lung cancer and EGFR mutation by electronic nose system. J Thorac Oncol. 12:1544–1551. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Lee WY, Chen PC, Wu WS, Wu HC, Lan CH, Huang YH, Cheng CH, Chen KC and Lin CW: Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ. Int J Cancer. 141:1921–1931. 2017. View Article : Google Scholar : PubMed/NCBI

16 

Ma W, Brodie S, Agersborg S, Funari VA and Albitar M: Significant improvement in detecting BRAF, KRAS, and EGFR mutations using Next-generation sequencing as compared with FDA-cleared kits. Mol Diagn Ther. 21:571–579. 2017. View Article : Google Scholar : PubMed/NCBI

17 

Singh PK and Silakari O: Novel EGFR (T790M)-cMET dual inhibitors: Putative therapeutic agents for non-small-cell lung cancer. Future Med Chem. 9:469–483. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Wang H, Tang M, Ou L, Hou M, Feng T, Huang YE, Jin Y, Zhang H and Zuo G: Biological analysis of cancer specific microRNAs on function modeling in osteosarcoma. Sci Rep. 7:53822017. View Article : Google Scholar : PubMed/NCBI

19 

Wang L, Zhang B, Zheng W, Kang M, Chen Q, Qin W, Li C, Zhang Y, Shao Y and Wu Y: Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway. Sci Rep. 7:53842017. View Article : Google Scholar : PubMed/NCBI

20 

Farooqi AA, Shu CW, Huang HW, Wang HR, Chang YT, Fayyaz S, Yuan SF, Tang JY and Chang HW: TRAIL, Wnt, sonic hedgehog, TGFβ, and miRNA signalings are potential targets for oral cancer therapy. Int J Mol Sci. 18:pii: E15232017. View Article : Google Scholar

21 

Li S, Zhang H, Ning T, Wang X, Liu R, Yang H, Han Y, Deng T, Zhou L, Zhang L, et al: MiR-520b/e regulates proliferation and migration by simultaneously targeting EGFR in gastric cancer. Cell Physiol Biochem. 40:1303–1315. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Yasukawa M, Kawaguchi T, Kawai N, Tojo T and Taniguchi S: Prognostic significance of mode of nodal involvement in pulmonary pN1 squamous cell carcinoma. Kyobu Geka. 71:163–168. 2018.(In Japanese). PubMed/NCBI

23 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

24 

Nia ES, Garland LL, Eshghi N, Nia BB, Avery RJ and Kuo PH: Incidence of brain metastases on follow-up 18F-FDG PET/CT scans of non-small cell lung cancer patients: Should we include the brain? J Nucl Med Technol. 45:193–197. 2017. View Article : Google Scholar : PubMed/NCBI

25 

Liang Y, Xu X, Wang T, Li Y, You W, Fu J, Liu Y, Jin S, Ji Q, Zhao W, et al: The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis. Cell Death Dis. 8:e29282017. View Article : Google Scholar : PubMed/NCBI

26 

Lu W, Zhang H, Niu Y, Wu Y, Sun W, Li H, Kong J, Ding K, Shen HM, Wu H, et al: Long non-coding RNA linc00673 regulated non-small cell lung cancer proliferation, migration, invasion and epithelial mesenchymal transition by sponging miR-150-5p. Mol Cancer. 16:1182017. View Article : Google Scholar : PubMed/NCBI

27 

Yuwen DL, Sheng BB, Liu J, Wenyu W and Shu YQ: MiR-146a-5p level in serum exosomes predicts therapeutic effect of cisplatin in non-small cell lung cancer. Eur Rev Med Pharmacol Sci. 21:2650–2658. 2017.PubMed/NCBI

28 

Lu Y, Tang L, Zhang Q, Zhang Z and Wei W: MicroRNA-613 inhibits the progression of gastric cancer by targeting CDK9. Artif Cells Nanomed Biotechnol. 46:980–984. 2018. View Article : Google Scholar : PubMed/NCBI

29 

Moles R: MicroRNAs-based therapy: A novel and promising strategy for cancer treatment. Microrna. 6:102–109. 2017. View Article : Google Scholar : PubMed/NCBI

30 

Qian H, Yang C and Yang Y: MicroRNA-26a inhibits the growth and invasiveness of malignant melanoma and directly targets on MITF gene. Cell Death Discov. 3:170282017. View Article : Google Scholar : PubMed/NCBI

31 

Zheng Z, Qu JQ, Yi HM, Ye X, Huang W, Xiao T, Li JY, Wang YY, Feng J, Zhu JF, et al: MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-kappaB signaling pathway. Cell Death Dis. 8:e28552017. View Article : Google Scholar : PubMed/NCBI

32 

Ren D, Yang Q, Dai Y, Guo W, Du H, Song L and Peng X: Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway. Mol Cancer. 16:1172017. View Article : Google Scholar : PubMed/NCBI

33 

Muralimanoharan S, Guo C, Myatt L and Maloyan A: Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity. Int J Obes (Lond). 39:1274–1281. 2015. View Article : Google Scholar : PubMed/NCBI

34 

Jiang L, Zhao Z, Zheng L, Xue L, Zhan Q and Song Y: Downregulation of miR-503 promotes ESCC cell proliferation, migration, and invasion by targeting cyclin D1. Genomics Proteomics Bioinformatics. 15:208–217. 2017. View Article : Google Scholar : PubMed/NCBI

35 

Yang X, Yin J, Xiang Q, Xie H, Yu J, Gan R and Lei X: MiR-503 sensitizes human hepatocellular carcinoma cells to cisplatin by targeting bcl-2. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 42:605–610. 2017.(In Chinese). PubMed/NCBI

36 

Lu YC, Cheng AJ, Lee LY, You GR, Li YL, Chen HY and Chang JT: MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44. Sci Rep. 7:20422017. View Article : Google Scholar : PubMed/NCBI

37 

Xiao J, Li G, Zhou J, Wang S, Liu D, Shu G, Zhou J and Ren F: MicroRNA-520b functions as a tumor suppressor in colorectal cancer by inhibiting DCUN1D1. Oncol Res. May 4–2017.(Epub ahead of print). View Article : Google Scholar

38 

Xiong F, Liu K, Zhang F, Sha K, Wang X, Guo X and Huang N: MiR-204 inhibits the proliferation and invasion of renal cell carcinoma by inhibiting RAB22A expression. Oncol Rep. 35:3000–3008. 2016. View Article : Google Scholar : PubMed/NCBI

39 

Yang Z, He M, Wang K, Sun G, Tang L and Xu Z: Tumor suppressive microRNA-193b promotes breast cancer progression via targeting DNAJC13 and RAB22A. Int J Clin Exp Pathol. 7:7563–7570. 2014.PubMed/NCBI

40 

Wang T, Gilkes DM, Takano N, Xiang L, Luo W, Bishop CJ, Chaturvedi P, Green JJ and Semenza GL: Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc Natl Acad Sci USA. 111:E3234–E3242. 2014. View Article : Google Scholar : PubMed/NCBI

41 

Su F, Chen Y, Zhu S, Li F, Zhao S, Wu L, Chen X and Su J: RAB22A overexpression promotes the tumor growth of melanoma. Oncotarget. 7:71744–71753. 2016. View Article : Google Scholar : PubMed/NCBI

42 

Zhou Y, Wu B, Li JH, Nan G, Jiang JL and Chen ZN: Rab22a enhances CD147 recycling and is required for lung cancer cell migration and invasion. Exp Cell Res. 357:9–16. 2017. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang L and Yu S: Role of miR‑520b in non‑small cell lung cancer. Exp Ther Med 16: 3987-3995, 2018.
APA
Zhang, L., & Yu, S. (2018). Role of miR‑520b in non‑small cell lung cancer. Experimental and Therapeutic Medicine, 16, 3987-3995. https://doi.org/10.3892/etm.2018.6732
MLA
Zhang, L., Yu, S."Role of miR‑520b in non‑small cell lung cancer". Experimental and Therapeutic Medicine 16.5 (2018): 3987-3995.
Chicago
Zhang, L., Yu, S."Role of miR‑520b in non‑small cell lung cancer". Experimental and Therapeutic Medicine 16, no. 5 (2018): 3987-3995. https://doi.org/10.3892/etm.2018.6732
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang L and Yu S: Role of miR‑520b in non‑small cell lung cancer. Exp Ther Med 16: 3987-3995, 2018.
APA
Zhang, L., & Yu, S. (2018). Role of miR‑520b in non‑small cell lung cancer. Experimental and Therapeutic Medicine, 16, 3987-3995. https://doi.org/10.3892/etm.2018.6732
MLA
Zhang, L., Yu, S."Role of miR‑520b in non‑small cell lung cancer". Experimental and Therapeutic Medicine 16.5 (2018): 3987-3995.
Chicago
Zhang, L., Yu, S."Role of miR‑520b in non‑small cell lung cancer". Experimental and Therapeutic Medicine 16, no. 5 (2018): 3987-3995. https://doi.org/10.3892/etm.2018.6732
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team