Progesterone hypersensitivity: Case report with favorable evolution

Senila,Simona   C.; Ungureanu,Loredana; Candrea,Elisabeta; Danescu,Sorina; Vasilovici,Alina; Cosgarea,Rodica; Dionisie,Vlad

doi:10.3892/etm.2018.7055

February-2019 Volume 17 Issue 2

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February-2019 Volume 17 Issue 2

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Case Report Open Access

Progesterone hypersensitivity: Case report with favorable evolution

Authors:
- Simona C. Senila
- Loredana Ungureanu
- Elisabeta Candrea
- Sorina Danescu
- Alina Vasilovici
- Rodica Cosgarea
- Vlad Dionisie
View Affiliations / Copyright

Affiliations: Department of Dermatology, University of Medicine and Pharmacy ‘Iuliu Hatieganu’, 400006 Cluj‑Napoca, Romania, Department of Psychiatry, Clinical Hospital of Psychiatry ‘Al. Obregia’, 041914 Bucharest, Romania

Copyright: © Senila et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 1125-1127
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Published online on: December 5, 2018

https://doi.org/10.3892/etm.2018.7055
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Abstract

Progesterone hypersensitivity or autoimmune progesterone dermatitis is characterized by heterogeneous skin eruptions that cyclically aggravate during the second half of the menstrual cycle, corresponding to a rise in the progesterone level. Clinical presentation is highly variable and includes all urticaria manifestations with or without angioedema, vesiculobullous, eczematous, purpuric or target‑like lesions on the skin and mucous membrane. Both endogenous progesterone as well as exogenous progestogens may represent an initial trigger. We report a case of progesterone hypersensitivity in a 27-year old woman with favorable evolution only on topical therapy, the positive clinical outcome being maintained during a subsequent pregnancy and postpartum period.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Progesterone hypersensitivity: Case report with favorable evolution

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