Open Access

Progesterone hypersensitivity: Case report with favorable evolution

  • Authors:
    • Simona C. Senila
    • Loredana Ungureanu
    • Elisabeta Candrea
    • Sorina Danescu
    • Alina Vasilovici
    • Rodica Cosgarea
    • Vlad Dionisie
  • View Affiliations

  • Published online on: December 5, 2018     https://doi.org/10.3892/etm.2018.7055
  • Pages: 1125-1127
  • Copyright: © Senila et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Progesterone hypersensitivity or autoimmune progesterone dermatitis is characterized by heterogeneous skin eruptions that cyclically aggravate during the second half of the menstrual cycle, corresponding to a rise in the progesterone level. Clinical presentation is highly variable and includes all urticaria manifestations with or without angioedema, vesiculobullous, eczematous, purpuric or target‑like lesions on the skin and mucous membrane. Both endogenous progesterone as well as exogenous progestogens may represent an initial trigger. We report a case of progesterone hypersensitivity in a 27-year old woman with favorable evolution only on topical therapy, the positive clinical outcome being maintained during a subsequent pregnancy and postpartum period.
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February-2019
Volume 17 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Senila SC, Ungureanu L, Candrea E, Danescu S, Vasilovici A, Cosgarea R and Dionisie V: Progesterone hypersensitivity: Case report with favorable evolution. Exp Ther Med 17: 1125-1127, 2019
APA
Senila, S.C., Ungureanu, L., Candrea, E., Danescu, S., Vasilovici, A., Cosgarea, R., & Dionisie, V. (2019). Progesterone hypersensitivity: Case report with favorable evolution. Experimental and Therapeutic Medicine, 17, 1125-1127. https://doi.org/10.3892/etm.2018.7055
MLA
Senila, S. C., Ungureanu, L., Candrea, E., Danescu, S., Vasilovici, A., Cosgarea, R., Dionisie, V."Progesterone hypersensitivity: Case report with favorable evolution". Experimental and Therapeutic Medicine 17.2 (2019): 1125-1127.
Chicago
Senila, S. C., Ungureanu, L., Candrea, E., Danescu, S., Vasilovici, A., Cosgarea, R., Dionisie, V."Progesterone hypersensitivity: Case report with favorable evolution". Experimental and Therapeutic Medicine 17, no. 2 (2019): 1125-1127. https://doi.org/10.3892/etm.2018.7055