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Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis

  • Authors:
    • Xuegu Xu
    • Yonghao Cai
  • View Affiliations / Copyright

    Affiliations: Department of Pharmacy, The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325003, P.R. China
    Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1224-1227
    |
    Published online on: December 10, 2018
       https://doi.org/10.3892/etm.2018.7079
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Abstract

Therapeutic effects and safety of houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis (VK) were evaluated. A total of 926 patients with VK were collected in the Eye Hospital of Wenzhou Medical University from July 2011 to January 2017. Patients were divided into group A, B and C according to the use of different eye drops. Group A included 276 patients who were treated with houttuynia eye drops; group B included 305 patients who were treated with olopatadine hydrochloride eye drops; group C included 345 patients who were treated with houttuynia eye drops and olopatadine hydrochloride eye drops. Treatment was performed for 14 days. Eye symptoms before and after treatment, and at 1 h, 7 days and 14 days after drug administration were compared among groups to evaluate the therapeutic effect. At 1 h after drug administration, highest excellent rate was observed in group C, followed by group A, and good outcome rate was significantly higher in group C than in the other two groups (P<0.05), and effective rate was also significantly higher in group C than in the other two groups (P<0.05). At 7 days after treatment, excellent rate was significantly higher in group C than in the other two groups (P<0.05), and effective rate was higher in group C than in group B (P<0.05). At 14 days after treatment, excellent rate was significantly higher in group C than in the other two groups (P<0.05), while lowest good outcome rate and ineffective rate were found in group C, and no significant differences were found between group A and B (P>0.05). Houttuynia ophthalmic solution and olopatadine hydrochloride eye drops can both achieve good effect in the treatment of VK, and combined use of them can increase the efficacy and shorten treatment period. So, the combined treatment should be popularized.
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Copy and paste a formatted citation
Spandidos Publications style
Xu X and Cai Y: Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis. Exp Ther Med 17: 1224-1227, 2019.
APA
Xu, X., & Cai, Y. (2019). Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis. Experimental and Therapeutic Medicine, 17, 1224-1227. https://doi.org/10.3892/etm.2018.7079
MLA
Xu, X., Cai, Y."Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis". Experimental and Therapeutic Medicine 17.2 (2019): 1224-1227.
Chicago
Xu, X., Cai, Y."Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis". Experimental and Therapeutic Medicine 17, no. 2 (2019): 1224-1227. https://doi.org/10.3892/etm.2018.7079
Copy and paste a formatted citation
x
Spandidos Publications style
Xu X and Cai Y: Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis. Exp Ther Med 17: 1224-1227, 2019.
APA
Xu, X., & Cai, Y. (2019). Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis. Experimental and Therapeutic Medicine, 17, 1224-1227. https://doi.org/10.3892/etm.2018.7079
MLA
Xu, X., Cai, Y."Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis". Experimental and Therapeutic Medicine 17.2 (2019): 1224-1227.
Chicago
Xu, X., Cai, Y."Therapeutic effects of Houttuynia eye drops combined with olopatadine hydrochloride eye drops on vernal keratoconjunctivitis". Experimental and Therapeutic Medicine 17, no. 2 (2019): 1224-1227. https://doi.org/10.3892/etm.2018.7079
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