Effect of transformer noise on the neurophysiology of SD rats

Zou,You; Yi,Xing; Zhang,Jian‑Gong; Liu,Xing‑Fa; Yang,Kun; Kong,Yong‑Gang; Xiao,Bo‑Kui; Tao,Ze‑Zhang; Chen,Shi‑Ming

doi:10.3892/etm.2019.7360

Effect of transformer noise on the neurophysiology of SD rats

Authors:
- You Zou
- Xing Yi
- Jian‑Gong Zhang
- Xing‑Fa Liu
- Kun Yang
- Yong‑Gang Kong
- Bo‑Kui Xiao
- Ze‑Zhang Tao
- Shi‑Ming Chen
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Affiliations: Department of Otolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China, China Electric Power Research Institute, Wuhan, Hubei 430070, P.R. China, Otolaryngology Head and Neck Surgery Institute, Medical School of Wuhan University, Wuhan, Hubei 430060, P.R. China
Published online on: March 7, 2019 https://doi.org/10.3892/etm.2019.7360
Pages: 3383-3390
Copyright: © Zou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Transformer noise is a type of environmental sound that causes discomfort to individuals. The aim of the present study was to determine the effect of relatively long‑term periods of transformer noise on the behavior and neurophysiology of SD rats. A total of 90 healthy SD rats with normal hearing were randomly divided into two experimental groups (65 and 60 dB group) and a control group. The experimental groups were exposed to recorded transformer noise for 8 weeks (sound level limits: 65 or 60 dB) and the control group was maintained under the same conditions without noise stimulation. Changes in physiological growth (weight tests), behavior (tail suspension and open field behavior tests) and neurophysiology (glutamate, γ‑aminobutyric acid, dopamine, 5‑hydroxytryptamine, the morphologies of hippocampi) following noise exposure were recorded and compared. The results revealed that rats exhibited normal physiological growth, with no significant difference between the experimental and control groups. Following noise exposure, no significant differences were observed in the results of behavioral experiments (tail suspension and open field behavior tests) between the experimental and control groups. In addition, there were no significant differences in glutamate, γ‑aminobutyric acid, dopamine and 5‑hydroxytryptamine levels or in the morphologies of hippocampi between groups. In conclusion, exposure to transformer noise with a sound level limit of 65 dB sound pressure level (SPL) or 60 dB SPL (spectral range, 100‑800 Hz) for 8 weeks (10 h/day) had no significant impact on the behavior and neurophysiology of SD rats.

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1	Di GQ, Zhou XX and Chen XW: Annoyance response to low frequency noise with tonal components: A case study on transformer noise. Appl Acoust. 91:40–46. 2015. View Article : Google Scholar
2	Teoh C, Soh K, Zhou R, Tien D and Chan V: Active noise control of transformer noise. Proceedings of the International Conference on Energy Management and Power Delivery. IEEE. (Singapore). 1998.
3	Waye KP, Clow A, Edwards S, Hucklebridge F and Rylander R: Effects of night-time low frequency noise on the cortisol response to awakening and subjectiv sleep quality. Life Sci. 72:863–875. 2003. View Article : Google Scholar : PubMed/NCBI
4	Leventhall HG: Low frequency noise and annoyance. Noise Health. 6:59–72. 2004.PubMed/NCBI
5	Kjellberg A, Tesarz M, Holmberg K and Landstrom U: Evaluation of frequency-weighted sound level measurements for prediction of low-frequency noise annoyance. Environ Int. 23:519–527. 1997. View Article : Google Scholar
6	Holmberg K, Landström U and Kjellberg A: Low frequency noise level variations and annoyance in working environments. J Low Freq Noise Vibrat Active Control. 16:81–87. 1997. View Article : Google Scholar
7	Muzet A: Environmental noise, sleep and health. Sleep Med Rev. 11:135–142. 2007. View Article : Google Scholar : PubMed/NCBI
8	Li Z and Di G: Reduce subjective annoyance from transformer noise by the method of sound adjustment. Acta Acust United Acustica. 102:452–461. 2016. View Article : Google Scholar
9	Olsen KN and Stevens CJ: Perceptual overestimation of rising intensity: Is stimulus continuity necessary? Perception. 39:695–704. 2010. View Article : Google Scholar : PubMed/NCBI
10	Lau S: Code for Design of Sound Insulation of Civil Buildings GB 50118-2010. (Beijing). China Building Industry Press. 2010.
11	Yong W and Ji ZY: Impact of transformer noise on indoor residential environment and control techniques. Environ Monit Forewarning. 2:44–45. 2009.
12	Van Campen LE, Murphy WJ, Franks JR, Mathias PI and Toraason MA: Oxidative DNA damage is associated with intense noise exposure in the rat. Hear Res. 164:29–38. 2002. View Article : Google Scholar : PubMed/NCBI
13	Coppola CL, Enns RM and Grandin T: Noise in the animal shelter environment: Building design and the effects of daily noise exposure. J Appl Anim Welf Sci. 9:1–7. 2006. View Article : Google Scholar : PubMed/NCBI
14	Demirel R, Mollaoğlu H, Yeşilyurt H, Üçok K, Ayçiçek A, Akkaya M, Genç A, Uygur R and Doğan M: Noise induces oxidative stress in rat. Eur J Gen Med. 6:20–24. 2009. View Article : Google Scholar
15	Kraus KS, Mitra S, Jimenez Z, Hinduja S, Ding D, Jiang H, Gray L, Lobarinas E, Sun W and Salvi RJ: Noise trauma impairs neurogenesis in the rat hippocampus. Neuroscience. 167:1216–1226. 2010. View Article : Google Scholar : PubMed/NCBI
16	Di G, Zhou B and Lin Q: The effects of aircraft noise exposure on rat behavior and serum neurotransmitter expression. Noise Control Eng J. 59:514–518. 2011. View Article : Google Scholar
17	Liu XF, Tang YM, Zhou B, Liu ZH, Wan BQ, Zhang JG, Li W, Qu M and Tang LJ: Experimental research on effect of transformer noise exposure below 65 dB on the neurotransmitter and nervoustissue in hippocampus of SD rats. High Volt Eng. 43:2486–2495. 2017.
18	Yost WA, Koita N, Maslo R and Patel P: Dosimeter measures of sound exposure experienced by university students. J Acoust Soc America. 120:3163. 2006. View Article : Google Scholar
19	Moses AJ: Measurement of magnetostriction and vibration with regard to transformer noise. IEEE Transact Magnet. 10:154–156. 1974. View Article : Google Scholar
20	Berglund B, Hassmén P and Job RFS: Sources and effects of low-frequency noise. J Acoust Soc Am. 99:2985–3002. 1996. View Article : Google Scholar : PubMed/NCBI
21	Smiley CS and Wilbanks WA: Some effects of noise exposure on early development in the albino rat. J Acoust Soc America. 67 (Suppl 1):S58–S59. 1980. View Article : Google Scholar
22	Lasky RE and Williams AL: Noise and light exposures for extremely low birth weight newborns during their stay in the neonatal intensive care unit. Pediatrics. 123:540–546. 2009. View Article : Google Scholar : PubMed/NCBI
23	Michaud DS, Miller SM, Ferrarotto C, Keith SE, Bowers WJ, Kumarathsan P, Marro L and Trivedi A: Exposure to chronic noise and fractionated X-ray radiation elicits biochemical changes and disrupts body weight gain in rat. Int J Radiat Biol. 81:299–307. 2005. View Article : Google Scholar : PubMed/NCBI
24	Yin C, Gou L, Liu Y, Yin X, Zhang L, Jia G and Zhuang X: Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice. Phytother Res. 25:1636–1639. 2011. View Article : Google Scholar : PubMed/NCBI
25	Steru L, Chermat R, Thierry B and Simon P: The tail suspension test: A new method for screening antidepressants in mice. Psychopharmacology. 85:367–370. 1985. View Article : Google Scholar : PubMed/NCBI
26	Barfield ET, Barry SM, Hodgin HB, Thompson BM, Allen SS and Grisel JE: Beta-endorphin mediates behavioral despair and the effect of ethanol on the tail suspension test in mice. Alcohol Clin Exp Res. 34:1066–1072. 2010. View Article : Google Scholar : PubMed/NCBI
27	Brenes Sáenz JC, Villagra OR and Fornaguera Trías J: Factor analysis of Forced swimming test, sucrose preference test and open field test on enriched, social and isolated reared rats. Behav Brain Res. 169:57–65. 2006. View Article : Google Scholar : PubMed/NCBI
28	van Kempen E, van Kamp I, Lebret E, Lammers J, Emmen H and Stansfeld S: Neurobehavioral effects of transportation noise in primary schoolchildren: A cross-sectional study. Environ Health. 9:252010. View Article : Google Scholar : PubMed/NCBI
29	Toyoda A, Iio W, Goto T, Koike H and Tsukahara T: Differential expression of genes encoding neurotrophic factors and their receptors along the septal-temporal axis of the rat hippocampus. Anim Sci J. 85:986–993. 2014. View Article : Google Scholar : PubMed/NCBI
30	Kim H, Lee MH, Chang HK, Lee TH, Lee HH, Shin MC, Shin MS, Won R, Shin HS and Kim CJ: Influence of prenatal noise and music on the spatial memory and neurogenesis in the hippocampus of developing rats. Brain Dev. 28:109–114. 2006. View Article : Google Scholar : PubMed/NCBI
31	Cheng L, Wang SH, Huang Y and Liao XM: The hippocampus may be more susceptible to environmental noise than the auditory cortex. Hear Res. 333:93–97. 2016. View Article : Google Scholar : PubMed/NCBI
32	Thiel CM, Müller CP, Huston JP and Schwarting RK: Auditory noise can prevent increased extracellular acetylcholine levels in the hippocampus in response to aversive stimulation. Brain Res. 882:112–119. 2000. View Article : Google Scholar : PubMed/NCBI
33	Ravindran R, Rathinasamy SD, Samson J and Senthilvelan M: Noise-stress-induced brain neurotransmitter changes and the effect of Ocimum sanctum (Linn) treatment in albino rats. J Pharmacol Sci. 98:354–60. 2005. View Article : Google Scholar : PubMed/NCBI
34	Cui B, Wu M, She X and Liu H: Impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. Brain Res. 1427:35–43. 2012. View Article : Google Scholar : PubMed/NCBI
35	Gil-Loyzaga P, Vicente-Torres MA, Fernández-Mateos P, Arce A and Esquifino A: Piribedil affects dopamine turnover in cochleas stimulated by white noise. Hear Res. 79:178–182. 1994. View Article : Google Scholar : PubMed/NCBI
36	Hassanvand T, Balooch M, Azarnia M and Zardooz H: Alterations in dopamine related behavior of the offspring of pregnant Wistar rats exposed to noise pollution stress. Physiol Pharmacol. 16:79–85. 2012.
37	Van Praag HM: 5-HT-related, anxiety- and/or aggression-driven depression. Int Clin Psychopharmacol. 9 (Suppl 1):S5–S6. 1994. View Article : Google Scholar
38	Turner CA, Clinton SM, Thompson RC, Watson SJ Jr and Akill H: Fibroblast growth factor-2 (FGF2) augmentation early in life alters hippocampal development and rescues the anxiety phenotype in vulnerable animals. Proc Natl Acad Sci USA. 108:8021–8025. 2011. View Article : Google Scholar : PubMed/NCBI