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Review Open Access

Immunologic adverse reactions of β-blockers and the skin (Review)

  • Authors:
    • Alin Laurentiu Tatu
    • Alina Mihaela Elisei
    • Valentin Chioncel
    • Magdalena Miulescu
    • Lawrence Chukwudi Nwabudike
  • View Affiliations / Copyright

    Affiliations: Medical and Pharmaceutical Research Unit/Competitive, Interdisciplinary Research Integrated Platform ‘Dunărea de Jos’, ReForm-UDJG; Research Centre in the Field of Medical and Pharmaceutical Sciences, Faculty of Medicine and Pharmacy, Department of Pharmaceutical Sciences, ‘Dunărea de Jos’ University of Galați, 800010 Galati, Romania, Department of Cardio-Thoracic Pathology, Faculty of Medicine, ‘Carol Davila’ University of Medicine and Phamacy, 050474 Bucharest, Romania, Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos University’ of Galati, 800010 Galati, Romania, Department of Diabetic Foot Care, ‘Prof. N. Paulescu’ National Institute of Diabetes, 011233 Bucharest, Romania
    Copyright: © Tatu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 955-959
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    Published online on: April 18, 2019
       https://doi.org/10.3892/etm.2019.7504
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Abstract

β-Blockers are a widely utilised class of medication. They have been in use for a variety of systemic disorders including hypertension, heart failure and intention tremors. Their use in dermatology has garnered growing interest with the discovery of their therapeutic effects in the treatment of haemangiomas, their potential positive effects in wound healing, Kaposi sarcoma, melanoma and pyogenic granuloma, and, more recently, pemphigus. Since β-blockers are deployed in a variety of disorders, which have cutaneous co-morbidities such as psoriasis, their pertinence to dermatologists cannot be overstated. Likewise, β-blockers, like any other drug category, carry risks of side effects, some of which are dermatologic. These include triggering and exacerbation of psoriasis, psoriatic and rheumatoid arthritis, anaphylaxis, contact dermatitis, occupational contact dermatitis, Raynaud's disease, alopecia, lichen planus-like drug eruption, hyperhydrosis and vitiligo. While recent articles have focussed on the positive uses of β-blockers, it may also be wise to call our attention to the potential dermatologic adverse effects that may follow β-blocker use, as well as possible therapeutic approaches to these. This short review will focus on those dermatoses resulting from β-blocker use, which have an immunologic basis.
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Spandidos Publications style
Tatu AL, Elisei AM, Chioncel V, Miulescu M and Nwabudike LC: Immunologic adverse reactions of β-blockers and the skin (Review). Exp Ther Med 18: 955-959, 2019.
APA
Tatu, A.L., Elisei, A.M., Chioncel, V., Miulescu, M., & Nwabudike, L.C. (2019). Immunologic adverse reactions of β-blockers and the skin (Review). Experimental and Therapeutic Medicine, 18, 955-959. https://doi.org/10.3892/etm.2019.7504
MLA
Tatu, A. L., Elisei, A. M., Chioncel, V., Miulescu, M., Nwabudike, L. C."Immunologic adverse reactions of β-blockers and the skin (Review)". Experimental and Therapeutic Medicine 18.2 (2019): 955-959.
Chicago
Tatu, A. L., Elisei, A. M., Chioncel, V., Miulescu, M., Nwabudike, L. C."Immunologic adverse reactions of β-blockers and the skin (Review)". Experimental and Therapeutic Medicine 18, no. 2 (2019): 955-959. https://doi.org/10.3892/etm.2019.7504
Copy and paste a formatted citation
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Spandidos Publications style
Tatu AL, Elisei AM, Chioncel V, Miulescu M and Nwabudike LC: Immunologic adverse reactions of β-blockers and the skin (Review). Exp Ther Med 18: 955-959, 2019.
APA
Tatu, A.L., Elisei, A.M., Chioncel, V., Miulescu, M., & Nwabudike, L.C. (2019). Immunologic adverse reactions of β-blockers and the skin (Review). Experimental and Therapeutic Medicine, 18, 955-959. https://doi.org/10.3892/etm.2019.7504
MLA
Tatu, A. L., Elisei, A. M., Chioncel, V., Miulescu, M., Nwabudike, L. C."Immunologic adverse reactions of β-blockers and the skin (Review)". Experimental and Therapeutic Medicine 18.2 (2019): 955-959.
Chicago
Tatu, A. L., Elisei, A. M., Chioncel, V., Miulescu, M., Nwabudike, L. C."Immunologic adverse reactions of β-blockers and the skin (Review)". Experimental and Therapeutic Medicine 18, no. 2 (2019): 955-959. https://doi.org/10.3892/etm.2019.7504
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