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Article Open Access

Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection

  • Authors:
    • Kaimei Xu
    • Jingjing Wang
    • Liu Yang
    • Liangbin Wan
    • Yanbing Wang
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, Bishan Hospital, Bishan, Chongqing 402760, P.R. China, Department of Anesthesiology, Bishan Hospital, Bishan, Chongqing 402760, P.R. China
    Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 949-954
    |
    Published online on: April 23, 2019
       https://doi.org/10.3892/etm.2019.7519
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Abstract

Malignant melanoma is a type of skin cancer with high morbidity and mortality. Therapeutic strategies should be individualized in order to increase the survival rate. The aim of this study was to assess the effect of lidocaine on skin healing and immune function after operation of patients with melanoma. Sixty patients with melanoma were selected from those treated in Bishan Hospital between August 2014 and August 2016. The patients were randomly divided into lidocaine group and control group. Lidocaine group was locally treated with an intradermic injection of 2% lidocaine solution in dose of 1.5 mg/kg and the control group received the same quantity of saline solution. In the lidocaine group, the rates of skin temperature, drug reaction, healing and infection were higher than the corresponding rates in the C group. The local application of lidocaine can promote wound healing to a certain extent, reduce pain, and promote postoperative skin reconstruction.
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Copy and paste a formatted citation
Spandidos Publications style
Xu K, Wang J, Yang L, Wan L and Wang Y: Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection. Exp Ther Med 18: 949-954, 2019.
APA
Xu, K., Wang, J., Yang, L., Wan, L., & Wang, Y. (2019). Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection. Experimental and Therapeutic Medicine, 18, 949-954. https://doi.org/10.3892/etm.2019.7519
MLA
Xu, K., Wang, J., Yang, L., Wan, L., Wang, Y."Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection". Experimental and Therapeutic Medicine 18.2 (2019): 949-954.
Chicago
Xu, K., Wang, J., Yang, L., Wan, L., Wang, Y."Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection". Experimental and Therapeutic Medicine 18, no. 2 (2019): 949-954. https://doi.org/10.3892/etm.2019.7519
Copy and paste a formatted citation
x
Spandidos Publications style
Xu K, Wang J, Yang L, Wan L and Wang Y: Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection. Exp Ther Med 18: 949-954, 2019.
APA
Xu, K., Wang, J., Yang, L., Wan, L., & Wang, Y. (2019). Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection. Experimental and Therapeutic Medicine, 18, 949-954. https://doi.org/10.3892/etm.2019.7519
MLA
Xu, K., Wang, J., Yang, L., Wan, L., Wang, Y."Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection". Experimental and Therapeutic Medicine 18.2 (2019): 949-954.
Chicago
Xu, K., Wang, J., Yang, L., Wan, L., Wang, Y."Effect of lidocaine on the safety of postoperative skin reconstruction after malignant melanoma resection". Experimental and Therapeutic Medicine 18, no. 2 (2019): 949-954. https://doi.org/10.3892/etm.2019.7519
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